42results about How to "Precise control of reaction conditions" patented technology

The invention discloses a hexafluropropylene oxide continuous production technique by using a microchannel reactor. The technique can avoid the phenomena of temperature runaway and oxidative burst, implements smooth temperature control, and has the advantages of high reaction conversion rate and favorable selectivity.

The invention discloses a method for synthesizing a coating printing thickening agent. The method comprises the steps of: preparation of polyurethane prepolymer, preparation of polyurethane-polyacrylic acid composite emulsion, dropwise addition of ammonia water into the composite emulsion for pH regulation, and the like. The high thickening capability of polyacrylic acid and the good diffusion resistant effect of polyurethane are utilized, an interpenetrating polymer network synthesis technology is adopted, and a novel coating printing thickening agent with high thickening capability and a good diffusion resistant effect is prepared by stepwise synthesis and accurate control over a reaction condition.

A kind of preparation method of lithium bisoxalate borate of the present invention relates to boron compound, and its process step is: the first step, raw material is mixed under the liquid phase condition and forms raw material slurry: analytically pure solid raw material ammonium oxalate, lithium iodide and The boron-containing oxygen compound is added to the aqueous ethanol solution, stirred and mixed evenly to form a raw material slurry; the second step, liquid phase reaction to prepare lithium bisoxalate borate slurry: the raw material slurry obtained in the first step is placed in an airtight container Inside, react to prepare lithium bisoxalate borate slurry; the third step, solid-phase burning to obtain lithium bisoxalate borate finished product: place the lithium bisoxalate borate slurry prepared in the second step in a vacuum oven , dried to powder, then placed in an electric furnace, heated to 200-240°C at a rate of 5-10°C / min, and then kept at this temperature for 1-6 hours to obtain the finished product of lithium bisoxalate borate. The process of the method of the invention is simple, and the obtained lithium bisoxalate borate product has high purity and high yield, and is suitable for large-scale production.

A method for preparing a hollow zirconia thin film by microfluidics, characterized in that: the steps of the method include: firstly prepare the material, that is, first prepare the ZrO2 2 Raw materials for ceramic thin films, followed by the preparation of ZrO by a microfluidic system 2 Gel film, obtained by ZrO 2 The gel membrane is sintered to obtain the target product. The application has the advantages that the microporous structure can be applied to fields such as filtration and purification, the thickness of the film is uniform, and it is easy to peel off from the substrate.

The present invention provides a preparation method of fluoro phosphate materials, comprising the following steps: adding into a sealed polytetrafluoroethylene-lined anti-corrosion austenitic stainless steel container ethyl-phosphate and iron powder with the mass of the iron powder being 1-2% of that of the ethyl-phosphate, a step of pumping nitrogen into the container to displace air when the temperature of the container reaches 80-92 DEG C via heating in a water bath, a step of slowly adding hydrofluoric acid liquor in a dropwise manner with a molar ratio of HF and (CH3CH2O)PO4 being 2.5-3.5:1], a step of pumping nitrogen into the container again after the adding step until the inner pressure of the container reaches 2-3 atmospheres, a step of ending the reaction by relieving the inner pressure to atmospheric pressure after the container maintains 2-6 hours of constant temperature, a step of distilling the obtained product under reduced pressure, and a final step of dewatering and filtrating the obtained product and therefore the required product is gained. The gained product in the present invention is free from acidic material such as hydrochloric acid produced by the prior art and capable of overcoming the following acidolysis phenomenon while water is the only material left in the product and can be removed. The preparation method has advantages of simple technological process, low cost and suitability for mass production.

A device, method and application for synthesizing a drug-loaded metal-organic framework material based on a microfluidic one-pot method, belonging to the field of drug-loaded metal-organic framework material synthesis. The device comprises a syringe a, a syringe b, a syringe c, a T-type connector a, a T-type connector b, a stainless steel capillary, a PTFE capillary, a constant temperature water bath and a collection tank, and the syringe a and the syringe b are respectively connected to the T-type The T-connector a is also connected to the stainless steel capillary, the stainless steel capillary passes through the T-connector b and is inserted into the PTFE capillary, the PTFE capillary is connected to the T-connector b, and the syringe c is connected to the T-connector b The middle part of the PTFE capillary is placed in a constant temperature water bath, and the other end of the PTFE capillary is connected to the collection tank. The invention has the advantages that the reaction conditions can be precisely controlled, the reproducibility is good, and the drug molecules are encapsulated inside the carrier, the drug loading efficiency is high, and the drug release efficiency is good.

The invention belongs to the technical field of organic synthetic processes, and relates to a method for preparing N-alkyl-4-nitrophthalimide by adopting N-alkyl phthalimide as a raw material, nitricacid as a nitrating agent, and performing low-temperature nitration reaction by virtue of a continuous flow to prepare the series product of N-alkyl-4-nitrophthalimide. The method is short in reactiontime and short in production period, solves the problems produced by the accumulation of raw materials in an intermittent reaction kettle, is more stable in the reaction process, and can significantly improve the reaction efficiency. The mass transfer performance and heat conduction performance in a micro-channel reactor of different structures can be improved, the constant reaction temperature can be kept, the temperature runaway phenomenon can be avoided, the generation of byproducts can be reduced, and the safety of the reaction process can be improved. By adopting the high mass transfer effect in the micro-channel reactor, a liquid-liquid reaction solution is sufficiently mixed, in the reaction process, the consumption of concentrated sulfuric acid and nitric acid can be greatly reduced, and the generation of waste acid can be reduced.

The invention provides an electrochemically modified carbon cloth reinforced friction material and a preparation method thereof. The method uses carbon fiber cloth and modified phenolic resin as raw materials, treats the carbon cloth under electrochemical conditions, selects a composite nickel source as the electrolyte, and adopts Carbon fibers are treated by anodic oxidation and cathodic deposition of metallic nickel. Then spray the modified phenolic resin solution on the treated carbon cloth, take it out and dry it naturally, and use a vulcanizing machine to form it by hot pressing. In the present invention, the carbon cloth is anodized and cathodically Deposition treatment increases the oxygen-containing functional groups on the surface of carbon cloth and uniformly deposits metallic nickel. It has the advantages of simple equipment and high efficiency. Metallic nickel has high hardness, wear resistance and catalytic activity, which greatly improves the bonding strength between carbon cloth and resin. , thereby improving the uniformity of the network polymer formed by the linear polymer through crosslinking during the vulcanization process, so that it has better tribological properties.