The invention discloses a preparation method of flaxseed concentrated
powder capable of inhibiting
premature ovarian failure and regulating
estrogen, which comprises the following steps: pretreating flaxseeds, crushing, and carrying out low-temperature spiral squeezing and deoiling to obtain
flaxseed meal of which the
residual oil rate is less than or equal to 3%; the preparation method comprises the following steps: mixing
flaxseed meal with water, adjusting the pH value, adding a compound
enzyme composed of
cellulase, hemicellulase and
protease according to a specific ratio, carrying out enzymolysis, and carrying out
enzyme deactivation to obtain an enzymatic
hydrolysate; performing at least two-stage water-phase ultrasonic-assisted extraction on the enzymatic
hydrolysate, and combining filtrates to obtain a crude extract; adding a
chitosan solution into the crude extract for
flocculation, carrying out
solid-liquid separation, and filtering the filtrate through a
ceramic membrane to obtain a purified solution; and finally, carrying out vacuum concentration and
spray drying on the purified liquid to obtain the flaxseed concentrated
powder. According to the method, the activity of
secoisolariciresinol diglucoside is efficiently reserved, the method is short in production period, green, safe and suitable for large-scale
continuous production, and the obtained product has definite and remarkable
biological activity in the aspects of inhibiting
premature ovarian failure and regulating
estrogen and is wide in market application prospect.