The invention belongs to the technical field of seaweed functional products, and particularly relates to fucoidin as well as a preparation method and application thereof, in particular to application of the fucoidin in food and preparation of medicines for
adjuvant treatment of age-related
maculopathy. According to the invention,
alginate lyase is adopted to carry out enzymolysis on seaweed, and the fucoidin with the molecular weight of 20-60 kDa is obtained
after treatment of multi-stage
alcohol precipitation,
hydrogen peroxide degradation and membrane interception. Experimental results show that the fucoidin has the effect of repairing
retinal cells, can effectively improve
maculopathy, can be used for preparing related products for treating age-related
macular degeneration, and provides
safer natural material support for treatment of age-related
macular degeneration.