71results about How to "Ease of large-scale synthesis" patented technology

The invention provides a synthetic peptide vaccine for a foot-and-mouth disease, and particularly relates to a polypeptide for an O-type synthetic peptide vaccine for the foot-and-mouth disease, a polypeptide polymer of the polypeptide, a vaccine containing the polypeptide or the polypeptide polymer, and preparation methods of the polypeptide or the polypeptide polymer and the vaccine. The polypeptide has an amino acid sequence shown in SEQ ID NO.3. The candidate polypeptide antigens are screened by a lot of animal tests, the antigen site of the foot and mouth disease virus is optimized according to the screening result, and T cell epitope and B cell epitope are effectively combined, so that the immune effect of the polypeptide antigen is enhanced. The O-type synthetic peptide vaccine for the foot-and-mouth disease can be used for effectively processing antigenic variation of foot-and-mouth disease viruses, is good in biosecurity and easy to synthetize at a large scale and has good application prospect.

The invention discloses a porous carbon-loaded cobalt-based Fischer-Tropsch synthesis catalyst containing a silicon dioxide auxiliary agent and a preparation method thereof. The catalyst uses cobalt as an active component, silicon dioxide as the auxiliary agent and porous carbon as a carrier, and the mass percentages of cobalt and silicon dioxide are 25.8 to 30.6% and 6.2 to 21.0% respectively, with the balance being the porous carbon carrier. Metallic cobalt particles are uniformly distributed on the catalyst and densely arrayed; the diameters of the particles are in a range of 6 to 9 nm; and the silicon dioxide auxiliary agent exists on the surfaces of the particles. According to the invention, a CO-MOF-71 metal-organic framework is used as a sacrificial template, a silicon source is doped by using an impregnation method, and then the silicon dioxide-supported porous carbon-loaded cobalt-based catalyst is prepared on a fixed bed through one-step in-situ pyrolysis method. The catalyst prepared in the invention has high specific active site density; and when applied to Fischer-Tropsch synthesis, the catalyst has good C<5+> selectivity, especially high C<5+> space-time yield, on the basis of high activity.