The invention discloses meat sauce as well as a preparation method and application, and belongs to the technical field of food. Components of the meat sauce comprise large minced meat, fermented soyabeans, vegetable oil, soybean paste or broad bean sauce, oyster sauce, dark soy sauce, yellow wine, white vinegar, crystal sugar, white sesame seeds, peanut seeds, a spicy material (1), a spicy material (2), a spicy material (3), green onions, garlic, gingers and thin soup. The meat sauce disclosed by the invention is reasonable in nutrient arrangement, and the phenomenon of malnutrition caused byeating excessive meat sauce is avoided; due to reasonable selection of used materials and consumption of the soya beans and the spicy materials (1), (2) and (3), the meat sauce is warm in nature, haseffects of dispersing wind and relieving exterior syndrome, clearing heat and relieving fidgetiness, dissolving thrombosis, detoxicating, regulating the meridians, soothing the liver and regulating Qi, warming the stomach and dispelling cold, invigorating the stomach and promoting the digestion, eliminating delays and resolving phlegm, and moistening dryness of intestines to stop diarrhea, and isa protective agent for bronchitis or other respiratory tract disorders; the protective agent is natural and has an aromatic flavor, can increase a sense of appetite and has a natural and anti-corrosion effect; and moreover, symptoms such as excessive internal heat and hypogeusia caused by eating the meat sauce are avoided, so that an effect of food therapeutic health with dinner is achieved.