The invention relates to a circuit board dust removal device, which includes a blower, a dust removal box, a box door, an air spray gun, a guide rail, a sliding cross bar, a pulley, an electrostatic filter, a fixed convex contact, a fixed pin hole, a groove and a fixed groove. The blower is installed at one end of the dust removal box, the other end of the dust removal box is provided with an electrostatic filter, the side wall of the dust removal box is provided with a box door, the inner wall of the dust removal box is provided with guide rails, and the two ends of the sliding bar pass through the central axis respectively. It is connected with the pulley, the pulley is embedded in the guide rail, and the pulley slides along the guide rail, three air spray guns are arranged at equal intervals on the sliding cross bar, grooves are arranged inside the blower, and two fixed protrusions are arranged on the two sides of the groove respectively. The designed circuit board dust removal device has good dust removal effect and is convenient and simple to operate.