This invention discloses the application of an
electrode material for reducing
intracellular resistance genes in
drug-
resistant bacteria. A
platinum-doped dendritic TiO2
nanowire structure based on a three-dimensional material is formed by growing a micron-sized TiO2 backbone array and
platinum-doped nano-sized TiO2 branches on the surface of a
porous electrode. The prepared dendritic
nanowire three-dimensional
electrode material has a larger specific surface area, providing more reactive sites and strong
electric field sites.
Platinum doping enhances the
conductivity and electrocatalytic performance of the nanowires. Furthermore, by combining it with
chloride salts / oxidants, the
electroporation and electrocatalysis of the
nanowire electrode surface are coupled. The strong
electric field confined at the nanowire tip induces perforation of the
drug-resistant bacterial
cell structure, strengthening the contact and reaction between the oxidant and the resistance
gene. The high electrocatalytic activity confined at the nanowire tip induces the generation of strong oxidizing free radicals, achieving the goal of destroying the
drug-resistant bacterial
cell structure and efficiently reducing
intracellular resistance genes.