30results about How to "Raise the enhancement factor" patented technology

The invention discloses a compound base of a precious metal nanometer array and single layer graphene and a preparation method thereof. The invention includes transferring the single layer graphene prepared by a chemical vapor deposition method to the precious metal nanometer array, keeping warm for 30 minutes under the temperature of 50 DEG C, firmly combining the single layer graphene and the precious metal nanometer array to form the compound base of the precious metal nanometer array and the single layer graphene. The preparation method is simple and easy to operate and low in raw material price. The obtained compound base is order in large area. The compound base can be applied to photoelectron devices and the fields of surface enhanced raman chips, thin film solar batteries and the like.

The invention discloses a preparation method of a large-area surface enhancement raman scattering substrate. The preparation method comprises the following steps: at first, the surface of a hard solid material is irradiated by femtosecond laser to prepare a large-scale hard microstructural mother set; then, polydimethylsiloxane (PDMS) is poured on the hard microstructural mother set by the nanoimprint lithography technology, and the structure on the hard microstructural mother set is copied to prepare a PDMS framework; and finally, a gold film is plated on the PDMS framework to prepare the PDMS surface enhancement raman scattering substrate. The experiment results show that the preparation method has the advantages that the enhancement factors are high, enhancement factors in different positions of the substrate have good uniformity, the large-area surface enhancement raman scattering substrate can be prepared, the mother set can be repeatedly imprinted, the production cost is reduced, and in addition, god is taken as raman enhancement metal, so that the defect that silver is oxidized very easily is avoided.

The invention belongs to the technical field of nano-imprinting and spectra, and in particular relates to a multilayer structure surface enhanced Raman scattering base and a preparation method thereof. The surface enhanced Raman scattering base is simple in process, high in efficiency, high in enhancement factor and biocompatible. The base consists of a substrate and a periodic nano columnar structure which is positioned on the substrate, wherein the nano columnar structure is a multilayer structure; the multilayer structure consists of alternation layers and a gold layer; the alternation layers consist of silver and media; the gold layer is positioned on the topmost layer. A nano-imprinting technology is used as a core technology, and a reactive ion etching process, a metal evaporation process, a silicon dioxide plating process, a metal peeling process and the like are combined to prepare a multilayer nano structure, so that the technical problems that a silver structure base is not biocompatible and a gold structure base is low in enhancement factor are solved; on the basis of ensuring biocompatibility, the enhancement factor of the base is greatly improved, the detection is efficient and sensitive, and the base can be applied to biological detection after further treatment.

The invention discloses a surface-enhanced Raman scattering substrate based on a surface plasmon polariton local-field coupling effect and a preparation method of the surface-enhanced Raman scattering substrate, and relates to a molecular detection and recognition technique and a preparation method of a metal micro/nano structure. The surface-enhanced Raman scattering substrate consists of the metal micro/nano structure with nano-scale gaps. The surface plasmon polariton local-field coupling effect exists in the gaps. The specific types of the surface-enhanced Raman scattering substrate comprises an Ag nano particle and Ag membrane coupling system, an Ag nano particle and Ag nano aperture array coupling system, and an Ag nano sphere cap and Ag nano aperture coupling system. The preparation method comprises a wet chemical method and a vacuum thermal evaporation deposition method. The preparation method of the surface-enhanced Raman scattering substrate is safe, simple and convenient, complex equipment is not required, the cost is low, the structure is stable and controllable, the repeatability is high and high enhanced factors can be provided at the same time.

The invention discloses a light irradiation preparation method and a use of an ultra-sensitive surface enhanced Raman scattering active base. The light irradiation preparation method comprises the following steps of: firstly, depositing silver nano particles on a surface of a DNA, then, taking the silver as a nucleation site to assemble the gold on the silver; and then, depositing small gold particles on a nano structure of silver-DNA by the sunlight again. The silver-nucleus gold-shell or silver-gold alloy nano DNA network structure is a good surface enhanced Raman scattering (SERS) active base obviously effective in TNT detection. The lowest detection limit can reach the prior lowest detection level, and enhancement factors can reach the order of magnitude of 1011-1012. The Light irradiation preparation method and the use of the ultra-sensitive surface enhanced Raman scattering active base provide a quick and accurate detection method for detecting explosives, such as TNT and the like.

The invention provides a preparation method of a surface-enhanced Raman substrate. The method comprises the following steps of: electrolyzing a silicon wafer in an electrolyte with hydrofluoric acid to prepare a porous silicon substrate; immersing the porous silicon substrate into a silver nitrate aqueous solution to react, then taking the porous silicon substrate out, and subsequently, drying the porous silicon substrate to prepare the surface-enhanced Raman substrate. The invention also provides an application of the surface-enhanced Raman substrate prepared by the method in trace detection of a surface-enhanced Raman spectrum, in particular an application in TNT (trinitrotoluene) detection.

The invention discloses a surface enhanced raman scattering substrate and a preparation method thereof. The preparation method comprises the following steps: preparing metal magnetic balls, each of which comprises a magnetic ball core and a noble metal shell layer coated on the outer surface of the magnetic ball core; preparing a plurality of limited range pits distributed in array on a preparation zone of a substrate main body; adding a magnetic field to the exterior of the substrate main body, repeatedly vibrating the magnetic field, thereby driving the metal magnetic balls on the surface ofthe substrate main body with the limited range pits to enter into the limited range pits and forming at least one metal magnetic ball layer along the depth direction of the limited range pits, wherein each metal magnetic ball layer is composed of a plurality of metal magnetic balls uniformly and closely arrayed in the limited range pits, and the metal magnetic balls of each metal magnetic ball layer are arrayed in a crystal-oriented form and in a hexagonal structure. The scheme is capable of solving the problems of high cost, complex process or low controllability of the prior art, reducing the processing cost of the surface enhanced raman scattering substrate and increasing the controllability of substrate hotspot forming and the controllability of an assembling process.

The invention provides a two-dimensional periodic V-shaped metal plasma resonance structure which comprises a substrate (1) and a metal film (2). The substrate (1) is in the shape of a V-shaped groove, and a slit is formed at the bottom of the V-shaped groove; the metal film (2) is arranged on the upper surface of the substrate (1) and is positioned in the V-shaped groove. The invention further provides a method for manufacturing the structure. The two-dimensional periodic V-shaped metal plasma resonance structure and the method have the advantages that the structure is extremely high in electromagnetic enhancement factor, target molecules can assuredly pass a resonance enhancement region of a local field when passing a detecting unit, and the high detecting sensitivity and high detecting precision are guaranteed.

The invention provides construction of a multi-layer structure surface enhanced Raman base and accurate regulation and control for performance of the construction, relating to the technical field of Raman detection. The construction comprises four steps of selecting a base, constructing a dual-layer nano-structure, pre-treating the dual-layer nano-structure and constructing a Raman base; a traditional single-layer structure can be transformed into a dual-layer structure through a simple replacement reaction, the enhancing factor of Raman is increased by 1.5 times; by electroplating or spinninggraphene, the Raman enhancing performance is further improved due to the graphene layer, which is 1.48 times that of the dual-layer structure, and the long-term stability of the base can be further improved. The multi-layer structure surface enhanced Raman base can be used for improving the limiting concentration of a traditional Raman base for detecting probe molecules and further improving enhancing factors of the traditional Raman base, and is low in cost and simple to operate; and the preparation process realizes rapid reaction without large reaction equipment, and accords with environment-friendly chemical concept.

The invention discloses a preparation method for a periodic metal material of a bicontinuous internal communicating structure and application of the periodic metal material. The preparation method comprises the steps that a biological template of the bicontinuous internal communicating structure is pretreated; nano-sized seed crystals are grown on the pretreated biological template; and the biological template with deposited nano-sized seed crystals is dipped in a precious metal chemical plating reducing solution for reaction. The periodic metal material prepared through the method has high-density three-dimensional distributed nano-sized band gaps and the high-scattering cross section, so that the periodic metal material has the ultrahigh plasma response efficiency. The detection limits of a surface enhanced Raman scattering (SERS) substrate manufactured through the periodic metal material to Rhodamine molecules and crystal violet molecules reach 10<-13> M and 10<-12> M correspondingly, enhancement factors of the substrate is up to 10<9>, and the high repeatability, homogeneity and stability are achieved.

The invention discloses a broadband plasmon composite structure and a preparation method thereof, and relates to the field of photoelectric materials and Raman detection. The plasmon composite nano-structure comprises a large-size nano-particle layer, a two-dimensional material layer arranged on the large-size nano-particle layer and small-size nano-particles arranged on the two-dimensional material layer. The preparation method of the broadband plasmon composite structure comprises the following steps: (1) firstly, depositing a metal film or a nano-particle layer on the surface of a substrate; (2) transferring the two-dimensional material to the surface of the prepared metal film or metal particle layer; (3) high-temperature annealing; and (4) deposition of small-size nanoparticles. Therefore, the composite nanostructure is configured into a plasmon resonance structure with a three-dimensional enhanced active site and a broadband enhancement effect, and can be used for detecting a surface enhanced Raman spectrum.

The invention discloses a flexible membranous material for SERS (Surface Enhanced Raman Scattering) detection and a preparation method of the flexible membranous material, and is characterized in thatthe material consists of two parts, namely gold nanoparticles and a polycaprolactone (PCL)/chitosan (CS) composite polymeric membrane, wherein the hydrophobicity of PCL and hydrophilia of chitosan allow the material to have both hydrophobicity and hydrophilia. and the gold nanoparticles have a surface Raman enhancement effect. The preparation method comprises the following steps: 1, preparing thePCL/CS composite film; 2, growing the gold nanoparticles on the composite membrane in situ, so that the surface Raman enhancement effect can be achieved, and the uniformity and reproducibility of SERS signals can be enhanced;.

The invention relates to a single-molecule detection method. The method comprises the following steps: providing a molecule carrier, wherein the molecule carrier comprises a substrate, and multiple three-dimensional nano-structures are arranged on one surface of the substrate; assembling a to-be-detected object molecule on the surface, far away from the substrate, of the three-dimensional nano-structure; detecting the to-be-detected object molecule assembled on the substrate by using a detector, wherein the three-dimensional nano-structures comprise a first cuboid structure, a second cuboid structure and a triangular prism structure; the first cuboid structure, the second cuboid structure and the triangular prism structure are orderly arranged on the surface of the substrate, the width ofthe triangular prism structure bottom surface is equal to the width of the upper surface of the second cuboid structure and greater than the width of the upper surface of the first cuboid structure, and the first cuboid structure and the triangular prism structure are metal layers.

The invention relates to a molecule detection device. The device comprises a molecule carrier, a detector and a control computer, wherein the molecule carrier comprises a substrate, an intermediate layer and a metal layer; the intermediate layer is arranged between the substrate and the metal layer; the detector is used for detecting the molecules of the object to be detected on the surface of themolecule carrier; the control computer is connected to the detector and is used for analyzing the detecting result; the substrate is a flexible substrate; the intermediate layer comprises a substrateplate, and a plurality of patterned bumps which are arranged on the substrate; and the metal layer is arranged on the surfaces of the patterned bumps.