Disclosed is a water quality purification method for a eutrophicated river, comprising the follow steps: first, blocking a eutrophicated river and forming an upstream part, a midstream part, and a downstream part; then entering the water in the upstream part into an electrolysis machine for electrolysis; discharging the electrolyzed water into the midstream part, and performing aeration treatment; lastly, letting the aerated water flow into the downstream part. By using a method of an electrolysis process and an aeration process in sequence, the algae growth in the water and the anaerobic reactions in the water body are effectively inhibited, organic matters are decomposed, the total nitrogen, total phosphorus, and color of the water are lowered, odors are eliminated, river water quality is improved within a relatively short period, and the water ecological system is restored. Also disclosed is a river water quality purification device, comprising a rubber dam, a pump, an electrolysis machine, and an aeration device. The device can be directly installed in the river and can directly purify river water without the need to guide the river into a pre-set structure for treatment. The present invention makes almost no change to the environment, and therefore has a relatively small impact on the natural environment.