The invention provides a multifunctional VHP sterilizer. The multifunctional VHP sterilizer comprises a machine body, an external drying system and a hydrogen peroxide solution cabinet are arranged on one side of the machine body, a Venturi nozzle is arranged at the top of the machine body, a VHP flash evaporator, a speed regulation air blower, a filter and a degradation device are arranged in the machine body, the VHP flash evaporator, the speed regulation air blower, the filter and the degradation device are all communicated with the external drying system and the hydrogen peroxide solution cabinet through parallel pipelines, the degradation device is communicated with the Venturi nozzle, and a first electric ball valve, a second electric ball valve and a three-in-one concentration probe are arranged on the parallel pipelines. The multifunctional VHP sterilizer provided by the invention has the advantages that the multifunctional VHP sterilizer can be used at room temperature, the sterilization period is short, the damage to a human body, equipment and the surrounding environment is reduced after operation, the penetrability to HEPA is relatively high, and the initial investment cost of the equipment is relatively low.