The invention discloses an LCD screen manufacturing technology making PI liquid and spacer mixed and belongs to the field of LCD production. The technology comprises the following steps that pretreatment is conducted, wherein the processes of first cleaning, resist coating, exposure, development, hardening, etching, stripping and second cleaning are conducted in sequence, and an ITO glass substrate is obtained; PI is dipped and cured, wherein the PI is dipped and then cured on the ITO glass substrate, and dipping and curing are completed; after-treatment is conducted, wherein the processes of PI rubbing, box printing, dot printing, combination of box printing and dot printing, cutting and liquid crystal injection are conducted in sequence, and an LCD screen is obtained. In the technology, the step of PI dipping comprises the steps that the PI liquid and the spacer are mixed two times and the PI is infiltrated, and the step of PI curing comprises the steps of PI pre-curing and main curing of the PI. According to the technology, in the PI dipping process, the spacer and the PI liquid are mixed two times, and the spacer is fixed into the PI liquid after pre-curing and main curing, so that the mixing effect is ensured; while the production rate of degraded products is reduced, the consumption of the spacer is reduced, and the cost is reduced.