4 results about "Botryotinia polyblastis" patented technology

The application discloses a kind of compounds with carbonyl coupling rigid fragment and its preparation method and bactericidal purposes.The compound has the structure shown in general formula I.A rigid carbonyl skeleton is constructed by connecting amino-containing 1,2,4-triazole through amide bond, and maleic acid structure and bioactive biological amine fragment are introduced, which are integrated in the same molecular skeleton by carbonyl coupling method.The compound synthesis route is short, the reaction condition is mild, and the yield is high.The biological activity test results show that the compound has broad-spectrum and significant inhibitory activity on rice sheath blight fungus, tomato botrytis cinerea, rice blast fungus, grape anthracnose fungus, oilseed rape sclerotinia sclerotiorum and many other plant pathogenic fungi.The compound has multi-target synergistic mechanism and low risk of drug resistance.

The present application relates to a fungicide for crops, and in particular to a composite fungicide containing plant extracts, a preparation process and application thereof.The composite fungicide comprises plant extracts and a fungicide preparation.The present application selects propineb and fluazinam in a weight ratio of 1:9-9:1 as the fungicide preparation, which can effectively prevent and control grape botrytis cinerea.In addition, plant extracts of chebula, oregano, thyme and sophora flavescens are used to optimize the performance of the extracts in inhibiting grape botrytis cinerea, and the composite fungicide containing plant extracts has good application prospect.

This invention discloses a method for detecting resistance to methoxyacrylate (QoIs) fungicides caused by single-base mutations in *Botrytis cinerea*, the causal agent of grape gray mold. This invention is based on the RPA-CRISPR / Cas12a system and designs a method targeting the fungicide. cytb This invention relates to a rapid, simple, and specific method for detecting resistance to Botrytis cinerea using a gene containing specific primer pairs with mutation sites and specific crRNA for activating Cas12a cleavage activity, combined with a fluorescent reporter probe. The method allows for real-time field detection without complex instruments, demonstrating promising application prospects and providing guidance for the healthy development of the grape industry and the scientific prevention of Botrytis cinerea.

The application relates to the technical field of chemical synthesis, and particularly discloses a synthesis method of a triplet carbene-mediated C2-substituted bicyclo[1.1.1]pentane derivative, which successfully opens up a synthesis path of C2-substituted bicyclo[1.1.1]pentane (BCP) by inserting bicyclo[1.1.0]butane (BCB) under photosensitive conditions; the 1,4-dibasic radical species generated by the triplet carbene has a faster recombination rate; the method not only lays a solid foundation for the application of bicyclo[1.1.1]pentane in medicinal chemistry, but also overcomes the limitation of traditional benzene rings in metabolic stability and water solubility by replacing a bioisostere and using a three-dimensional bridged ring structure. In addition, the synthesized derivatives exhibit excellent biological activity, and experimental data prove that the derivatives have significant fungal inhibition activity in tests such as botrytis cinerea, thereby providing important technical support for the design and development of new drugs.