53results about How to "Achieve anti-inflammatory effect" patented technology

The invention relates to a cyclodextrin inclusion drug composition for ocular inflammation resistance, which consists of vitamin C or a derivative thereof as an active ingredient, glucocorticoid, cyclodextrin and one or more pharmaceutically acceptable pharmaceutical excipients capable of acting on eyes, wherein the glucocorticoid and / or the derivative of the vitamin C are included by the cyclodextrin.

The invention discloses a compact-type water-soluble human lubricant, a preparation method of the lubricant, and a condom using the lubricant. The compact-type water-soluble human lubricant comprises the following components in percentage by weight: 30-47% of glycerol, 2-4% of tween-20, 0.05-0.15% of sodium hyaluronate, 0.1-0.3% of jasminum essential oil, 0.5-1.2% of aloe essential oil, and 48-66% of water. The compact-type water-soluble human lubricant has good compatibility with the naturally-selected body fluid of human body, is not greasy, has a pH value as same as the pH value of the normal physiological environment of female vagina, and has the effects of nourishing vaginal tissues, promoting cell growth, increasing muscle elasticity, and improving vaginal relaxation.

The invention discloses a whitening composition and the application thereof in whitening cosmetics. The whitening composition contains the following components in weight percentage: 1-10% of lipid soluble VC derivatives, 0.05-0.2% of Glabridin, 1-5% of nicotinamide, 1-5% of hydrogenated soya lecithin, 0.1-0.5% of a gorgonia extracting solution and 0.5-2% of an amino-acid humectant. According to the whitening composition prepared by the invention, the whitening and speckle removing effects are obvious, the whitening composition can be quickly adsorbed by skin, the irritation to the skin is weak and the obvious moisture-holding, anti-inflammatory and antiallergic effects and effective skin brightening effect are realized.

The invention provides a beautifying cream and a preparation method thereof and belongs to the technical field of daily-use skincare products. The beautifying cream a phase A, a phase B, a phase C, aphase D and the balance water, wherein the phase A comprises 1,3-propylene glycol, glycerin, p-hydroxyacetophenone, purslane extract and the like; the phase B comprises isononyl isononanoate, dicaprylyl carbonate, caprylic / capric triglyceride and the like; the phase C comprises pearl powder, matrine and erythritol; the phase D comprises potato starch, Angelica keiskei leaf stem extract, Chinese herbal medicine extract, Chinese herbal medicine root extract, Chinese herbal medicine root powder and the like. The beautifying cream is prepared through heating, homogenous stirring, heat preservation, cooling, mixing, discharging and filling. The beautifying cream has evident effects of removing acne, moisturizing, repairing and resisting aging and is mild and safe to the skin, capable of solvingvarious daily skin problems and capable of saving trouble. In addition, the preparation method is simple to operate and capable of favorably protecting the activity of various components and bringingthe corresponding effects of the components into play.

The invention relates to an external analgesic traditional Chinese medicine and particularly discloses an external plaster with relieving and treating effect on the pain from bone metastases of a cancer patient and a preparation method thereof. The external plaster is prepared by reasonably blending the common traditional Chinese medicines such as radix aconiti kusenzoffii, ephedra, asarum, raw rhubarb, rhizoma sparganii, frankincense and myrrh. The external plaster is rapid in analgesic effect, small in side effect, economical and practical and relieves the economical burden of the cancer patient and particularly has good adaptability on the middle and late period cancer patient.

The invention discloses a research method for effect of the extract of modified five-ingredient toxin-dispersing beverage to carrageenan-induced inflammation in mice. According to the method, the five-ingredient toxin-dispersing beverage is as a base, and is modified by adding two Chinese medicinal herbs of root of kudzu vine and red sage root. The method comprises: by using water extraction and alcohol precipitation, extracting and separating a crude extract of the modified five-ingredient toxin-dispersing beverage; by using the classic model of carrageenan-induced paw edema in mice, observing the anti-inflammatory effect of the extract; and determining the influence of the extract to tumor necrosis factor-alpha and interleukin-6 in serum of mice. By using the research method for the effect of the extract of modified five-ingredient toxin-dispersing beverage to carrageenan-induced inflammation in mice of the invention, the conclusion that the effect of the extract of modified five-ingredient toxin-dispersing beverage has inhibiting effect for the tumor necrosis factor-alpha and the interleukin-6 levels, which means that the anti-inflammatory effect of the extract is achieved by inhibiting the secretion of inflammatory cytokines and provides experimental basis for the application of the extract in nonbacterial inflammatory disease.

The invention belongs to the technical field of cosmetics intelligence. The intelligent facial mask is composed of a mobile phone APP operating system, an intelligent host 'medium-frequency pulse introducing instrument' and a face pasting membrane. A working procedure is divided into three steps of cleansing, introducing and relieving. According to the principle, the intelligent host with a biological negative current (3V negative current) is utilized for conducting pore dredging and skin cleansing on skin through micro-frequency vibration, essence ingredients in the facial mask are introduced into skin deep layers, absorption of skin to nutrient substances and active substances is promoted, the skin is released, and the using efficiency of the facial mask is improved. The whole process is monitored through the mobile phone APP operating system, the skin conditions before and after the facial mask applying process are embodied digitally, and a rationalized skin care suggestion is given out; and a personalized and customized facial mask using manner is really achieved.

The invention provides a preparation method of a herba houttuyniae and rice fermentation product filtrate composition, and relates to the technical field of microbial fermentation and cosmetics. The preparation method comprises the following steps of: 1, washing and drying herba houttuyniae and rice in the sun, and carrying out crushing with a crusher; 2, preparing a mixed fermentation liquid from the following components in parts by weight: 3-10% of herba houttuyniae powder, 3-10% of rice meal, 2-5% of yeast liquid and the balance of water; 3, inoculating saccharomycetes activated by a table concentrator into a culture medium for carrying out fermentation; and 4, after the fermentation is finished, inactivating bacterial liquid, filtering and collecting filtrate, carrying out proportioning according to a certain proportion, and adding a preservative. The preparation has a simple technology and can effectively solve the problems of serious chemical pollution and insufficient mildness in cosmetics. The active ingredients of the herba houttuyniae in the filtrate have an obvious antibacterial and anti-inflammatory effect, and can be applied to the fields of beautifying, skin care and the like.

The invention discloses a spraying pipe assembly with LED physiotherapy lamps and a closestool with the spraying pipe assembly. The spraying pipe assembly comprises a support, a spraying pipe which ismovably arranged on the support, an LED physiotherapy lamp assembly which is arranged on the spraying pipe, an ultraviolet lamp sterilizing assembly and a driving mechanism. The spraying pipe comprises a stainless steel pipe and one or more water pipes. The stainless steel pipe is provided with a visible window and one or more water spraying openings. The water pipes correspond to the water spraying openings one to one. The LED physiotherapy lamp assembly comprises a shell, at least two convex lenses and at least two LED physiotherapy lamps. The spraying pipe has a first state and a second state. In the first state, the spraying pipe is opposite to the support, and the ultraviolet lamp sterilizing assembly is opposite to the water spraying openings; in the second state, the spraying pipeextends out of the support. The designed purple light LED physiotherapy lamp has the sterilizing and inflammation eliminating effects, the red light LED physiotherapy lamp has the effects of accelerating the blood circulation, promoting the wound healing, whitening the skin and preventing chromatosis, and the closestool has a physiotherapy function.

The invention discloses a compound eucommia ulmoides concentrated solution for improving the resistance of cows in the perinatal period. The solution comprises 30-35 parts of rumen bypass glucose, 10-15 parts of calcium gluconate, 8-12 parts of potassium gluconate, 25-35 parts of magnesium dipropionate, 15-20 parts of iodised salt iodized salt, 25-30 parts of soda powder, 6-8 parts of vitamin A, 5-8 parts of vitamin D, 10-15 parts of vitamin E, 10-15 parts of selenium, 1-5 parts of vitamin B12 and 1-2 parts of the eucommia ulmoides concentrated solution. The compound eucommia ulmoides concentrated solution is high in safety, easy to prepare and low in preparation cost, the raw materials are easily obtained, the nutrient, microelements and mineral elements required by the cows after delivery can be supplemented in time, the mastitis, low calcemia and other diseases caused by energy metabolic diseases and immunosuppression of the cows in the perinatal period can be well prevented and treated, the milk quality can also be improved, the milk yield is increased, the breeding cost can be lowered, and the solution has high economic benefit.

The invention relates to an external application traditional Chinese medicine for relieving pain and particularly relates to an external application plaster for treating skeletal metastatic cancer pain and a preparation method of the external application plaster, wherein the external application plaster has effects on relieving and treating the skeletal metastatic pain of cancer patients. The external application plaster is prepared by reasonably blending common traditional Chinese medicines such as unprocessed radix aconiti, ephedra, asarum, raw rhubarb, peach kernels, rhizoma sparganii, olibanum and myrrh. The external application plaster is rapid in taking effects and few in side effects when being used for relieving pain, is economic and practical, is capable of reducing the economic burdens of cancer patients, and is particularly good in adaptability for middle and advanced cancer patients.

The invention discloses a cleansing, acne-removing and repairing mask which comprises an extract of radix toddaliae asiaticae, an extract of rhizoma polygonati and an extract of radix docynia delavayi serving as active ingredients, which give the mask effects of cleansing pores, removing acnes mildly and promoting repair. In addition, the mask provided by the invention further contains ethanol, propylene glycol and other ingredients, which have good water replenishing and reserving force, not only promotes absorption of plant active ingredients, but also forms a water reserving film on skin, and increases moisture of the skin.

The invention discloses an itching-relieving skin care product which contains populus tomentosa carr and can be smeared. The itching-relieving skin care product is prepared from, by weight, 25-35 parts of populus tomentosa carr, 3-8 parts of seaweed powder, 1-3 parts of sodium alginate and 100-120 parts of water. The raw materials are natural and non-irritant, do not produce dependence, is scientific and reasonable in proportion, can give full play to the itching-relieving, anti-inflammatory, antibacterial and skin repairing effect, and the like. The itching-relieving skin care product is especially applicable to senile cutaneous pruritus, eczema and the like, can also be suitable for pregnant women, nursing mothers and children, meanwhile can also play a nursing effect to the skin and has wide application prospect.

The invention discloses a traditional Chinese medicine for treating liver depression and spleen deficiency. The traditional Chinese medicine is mainly prepared from, by weight, radix bupleuri, radix angelica sinensis, radix paeoniae alba, poria cocos, rhizoma atractylodis macrocephalae, radix codonopsis, milkvetch roots, fresh ginger, herba menthae, fructus aurantii immaturus, honey-fried licorice roots, rhizoma chuanxiong, dried tangerine peel, rhizoma acori tatarinowii, rhizoma cyperi, fructus amomi, semen ziziphi spinosae, cortex albiziae, dry radix ginseng and barbary wolfberry fruits. The traditional Chinese medicine materials are used in a matched mode, the traditional Chinese medicine has the advantages of being significant in curative effect and capable of treating both symptoms and root causes, and the relapse is less likely to occur after healing. In addition, the traditional Chinese medicine is prepared from pure traditional Chinese medicine, and therefore the traditional Chinese medicine has the advantages of being small in toxic and side effects, low in treatment cost and the like.

The invention relates to a polyacetylene compound and application thereof. The polyacetylene compound is separated from sporophore of antrodia cinnamomea and has the effect of inhibiting generation of nitric oxide, so the polyacetylene compound can be used for preparing a pharmaceutical composition having an anti-inflammatory effect. The invention improves that the sporophore of antrodia cinnamomea has a physiological metabolism substance with representative significance, and the substance can be applied in evaluation of quality of antrodia cinnamomea.

The invention relates to a traditional Chinese medicine aerosol for treating upper respiratory diseases of poultry and a preparation method of the traditional Chinese medicine aerosol, and belongs tothe field of animal husbandry and veterinary medicine. The traditional Chinese medicine aerosol for treating the upper respiratory diseases of poultry is prepared from the raw materials in parts by weight: 2 parts of ligustici rhizoma et radix, 1 part of tangerine peel, 0.5-1 part of mint, 0.5-1 part of asariradix et rhizoma, 0.5 part of dried ginger, 2.5-3 parts of ethanol, and 1.5-2 parts of dimethyl ether. The traditional Chinese medicine aerosol is used for treating the upper respiratory diseases of poultry and has excellent curative effect and good atomization effect, and the spray rate is not less than 1.3g / s, so that intensive breeding and dosing are facilitated.

The invention relates to the technical field of oral care, in particular to cordyceps militaris essence particles, cordyceps militaris toothpaste and preparation methods of the cordyceps militaris essence particles and the cordyceps militaris toothpaste. The cordyceps militaris essence particles comprise cordyceps militaris essence and wrapping layers wrapping the cordyceps militaris essence. Wherein the wrapping layer sequentially comprises an inner layer and an outer layer from inside to outside, the inner layer comprises microcrystalline cellulose, mannitol and corn starch, and the outer layer comprises a polymer. According to the invention, a two-layer wrapping mode is adopted; a mixture of microcrystalline cellulose, mannitol and corn starch, which does not influence the activity of the cordyceps militaris essence, is directly contacted with the cordyceps militaris essence, and then the wrapping layer prepared by the high-molecular polymer is arranged on the outer layer, so that permeation of other substances except water molecules in the toothpaste can be effectively isolated, the cordyceps militaris essence is fundamentally protected, the efficacy of the cordyceps militaristoothpaste can be effectively exerted within the shelf life, and the antibacterial and anti-inflammatory effects are achieved.

The invention provides a formula of facial mask powder with effects of maintaining beauty and keeping young and belongs to the field of beauty maintaining and young keeping. The facial mask powder comprises raw materials in parts by weight as follows: 5-10 parts of radix codonopsis, 5-10 parts of venenum bufonis, 5-10 parts of lavender, 10-20 parts of mung bean, 5-10 parts of flos lonicerae, 5-10 parts of flos chrysanthemi, 3-8 parts of radix sophorae flavescentis, 3-8 parts of periostracum cicadae, 10-20 parts of lotus root, 5-10 parts of rhizoma bletillae, 5-10 parts of radix angelicae sinensis, 5-10 parts of rhizoma ligustici, 5-10 parts of cuttlebone, 5-10 parts of feaces vespetilio, 10-15 parts of green tea, 10-20 parts of orange peel and 10-20 parts of pearl powder. The invention further discloses a preparation method and an application method of the facial mask powder with the effects of maintaining beauty and keeping young. The facial mask powder with the effects of maintaining beauty and keeping young is prepared from Chinese herbal medicines, treat skin deeply, achieves the purposes of inflammation diminishing and beauty maintaining, has remarkable effect and is safe and free of side effects.

The invention belongs to the technical field of biological medicine, and particularly relates to application of folium artemisiae argyi volatile oil to inhibition of activation of NLRP3 inflammasomes.The invention discloses application of the folium artemisiae argyi volatile oil to inhibition of activation of NLRP3 inflammasomes in a Nigericin and monosodium urate induced THP-1 cell inflammationmodel. Researches show that the folium artemisiae argyi volatile oil can inhibit activation of agonists with different attributes such as nigericin and mono sodium urate (MSU) on the NLRP3 inflammasomes, which is mainly manifested in inhibiting NLRP3 expression, ASC oligomer formation, cleavage activation of procaspase1, and the like, so that generation of inflammatory cytokines IL-l-beta, IL18 and TNF-alpha is inhibited, and finally an anti-inflammatory effect is achieved. Therefore, the folium artemisiae argyi volatile oil can be used as a medicine or compound medicine component for preventing or treating NLRP3 inflammasome related inflammatory diseases.

The invention discloses kudzuvine root tea with effects of clearing heat and diminishing inflammation and relates to the field of drinks. The kudzuvine root tea comprises the components as follows: 30-40 g of kudzuvine roots, 20-30 g of water chestnuts, 5-10 g of corn stigma, 10-20 g of fresh ginger, 1-2 g of xylooligosaccharide and 20-40 g of probiotic powder. The prepared kudzuvine root tea is convenient to make, comprises multiple scientifically matched components, has the effects of clearing heat and diminishing inflammation and can effectively improve the micro-ecological balance of hosts, enhance immunity of hosts and improve health of hosts.

The invention provides a composition for relieving stimulation of vitamin A and a preparation method of the composition, and relates to the technical field of skin care. The composition for relieving the stimulation of the vitamin A is prepared from the following raw materials in parts by weight: 0.05 to 0.3 part of hydroxyl pinacolone retinoate, 0.01 to 0.3 part of retinol palmitate, 0.01 to 0.2 part of retinol, 0.01 to 0.2 part of rosa palmifolia fruit oil, 0.1 to 0.9 part of carnosine, 0.01 to 0.2 part of acetyl hexapeptide-8, 0.1 to 2 parts of panthenol, 1 to 5 parts of simmondsia chinensis seed oil, 0.1 to 0.4 part of bisabolol, 0.03 to 0.3 part of herba centellae extract and 85 to 95 parts of water. Through matching of different components, irritation of the vitamin A to skin when the vitamin A is applied to the skin care product is relieved, the vitamin A component can better play roles in promoting collagen synthesis and accelerating metabolism, and the effects of whitening, resisting aging and tightening fine wrinkles of the skin care product are enhanced.

The invention discloses toothpaste capable of diminishing inflammation and resisting allergy and a preparation method thereof, belonging to the technical field of oral care. The toothpaste comprises the following components: a humectant, an abrasive, a thickener, a surfactant, a sweetening agent, a preservative, medicinal components and a balancing amount of water. In the process of implementation, it is accidentally found that when calcium hydrophosphate and silicon dioxide are mixed to serve as an abrasive, the particle size of the calcium hydrophosphate is controlled to be 12-18 [mu]m, theparticle size of the silicon dioxide is controlled to be 6-10 [mu]m, and a mass ratio of the calcium hydrophosphate to the silicon dioxide is controlled to be 1: (1-5), prepared toothpaste has good cleaning performance, can obviously improve the removal of dental plaque, and can reduce the abrasion of the toothpaste to teeth; and when sodium benzoate is mixed with medicinal components including ilex rotunda thunb extract and cimicifuga foetida extract, the antibacterial performance of the toothpaste can be obviously improved, and better anti-inflammatory effect can be achieved.

The invention relates to a cyclodextrin inclusion drug composition for ocular inflammation resistance, which consists of vitamin C or a derivative thereof as an active ingredient, glucocorticoid, cyclodextrin and one or more pharmaceutically acceptable pharmaceutical excipients capable of acting on eyes, wherein the glucocorticoid and / or the derivative of the vitamin C are included by the cyclodextrin.

The invention discloses a novel shock wave therapy coupling agent with anti-inflammatory and pain relieving functions. The coupling agent adopts a drug-loading hyaluronic acid nano microemulsion, anda loaded drug is a non-steroid anti-inflammatory drug. The invention further discloses a preparation method of the novel shock wave therapy coupling agent with anti-inflammatory and pain relieving functions. By use of good transdermal absorption and moisturizing and lubricating characteristics of hyaluronic acid, the modified drug-loading hyaluronic acid nano microemulsion is prepared, the drug-loading hyaluronic acid nano microemulsion can be applied to the in vitro shock wave coupling agent and can be matched with shock waves, so that the transdermal absorption effect of the anti-inflammatory drug coated by the drug-loading hyaluronic acid nano microemulsion can be improved under the action of shock wave energy, the anti-inflammatory effect of shock wave therapy and transdermal drug delivery therapy can be enhanced significantly, the operation is simple, and the clinical therapeutic effect is significantly.

The invention discloses a modified blood purification membrane and a preparation method thereof, and belongs to the technical field of medicine and pharmacology. The preparation method comprises the following steps: (1) preparing a chloromethylated polymer; (2) preparing a fingolimod modified polymer; and (3) preparation of the fingolimod modified polymer film. The invention also provides the modified blood purification membrane obtained by the preparation method. The fingolimod is grafted to polysulfone or polyethersulfone, so that the prepared modified blood purification membrane has better blood compatibility, can directly inhibit lymphocyte activity to achieve an anti-inflammatory effect, and can improve hydrophilic performance through hydroxyl of the fingolimod while effectively resisting inflammation, thereby reducing formation of thrombus and improving the blood purification effect. The medicine is suitable for treatment of patients with various severe infections and multi-organ function failure. The preparation method disclosed by the invention is safe and simple, can be realized through a two-step synthesis method, is relatively short in preparation period and can be suitable for industrial batch production.

The invention relates to the technical field of biological medicine, and provides an application of a pyrimidinedione compound as a microsome prostaglandin E2 synthase inhibitor. The microsome prostaglandin E2 synthase inhibitor is a pyrimidinedione compound, and the pyrimidinedione compound is 2-{[((3-chlorphenyl)methyl]sulfanyl}-5-(3, 4-dihydroxyphenyl)-3H, 4H, 5H, 6H, 7H, 8H-pyridyl[2, 3-d]pyrimidine-4, 7-dione (CLOS for short), and reflects anti-inflammatory activity by remarkably reducing generation of PGE2 and inhibiting activity of mPGES-1 protein and further regulating expression of the mPGES-1 protein to inhibit generation of the PGE2; meanwhile, the CLOS has no obvious influence on COX-1 and COX-2, so that the CLOS can be used for treating inflammation, does not cause side effects of cardiovascular diseases and has a good effect.

The invention discloses an application of a hydrogel nano carrier in anti-inflammatory anti-aging cream. The anti-inflammatory anti-aging cream comprises an anti-inflammatory anti-aging composition, hydroxyethyl cellulose-sodium alginate hydrogel and the like, wherein the anti-inflammatory anti-aging composition comprises a rosin leaf extract, gynostemma pentaphyllum, ascorbyl glucoside, vitamin E, sorbitan monooleate, glycerol, allantoin and the like. According to the invention, the hydrogel nano carrier in anti-inflammatory anti-aging cream is prepared by wrapping anti-inflammatory components and anti-aging components by using the hydroxyethyl cellulose-sodium alginate hydrogel, and the hydroxyethyl cellulose-sodium alginate hydrogel is a nanometer carrier, and can be quickly absorbed byskins to pass through the cell membranes, so that the anti-inflammatory components and the anti-aging components are loaded into the skin cells, go deep into the skin to remove excess free radicals,and promote degradation of skin cutin and proliferation and metabolism of cells in the epidermal basa layer to enable the skin to be tender and elastic.

The invention relates to the technical field of edible fat, in particular to sesame oil having efficacy of diminishing inflammation and repairing neural injury and a preparation method of the sesame oil. The sesame oil consists of the following components of sesame seeds, apricot kernels, herba ephedrae, radix puerariae, licorice roots, hazelnuts and rapeseeds. The sesame oil made by the preparation method disclosed by the invention promotes increment and expression strengthening of brain-derived nerve growth factors after hypoxia ischemia, and due to the expression strengthening of brain-derived nerve growth factors, the injury degree of affected neurons can be reduced, injury nerve cells are induced to be repaired, the lung injury coefficients can also be obviously reduced, the neutropenia aggregation is reduced, and the lipid peroxidation is reduced; and in addition, the generation of oxygen-derived free radicals, inflammatory mediators and tumor necrosis factors is restrained, and the content of glutathione peroxidase is increased, so that the efficacy of resisting inflammation is achieved. A biological fermentation technology, a third-class film concentration technology and the like are adopted, so that the purity of extracted ephedrine is higher than that made by a conventional technology, and the highest extraction rate of the ephedrine is 98.53%.

The invention relates to a traditional Chinese medicine aerosol for treating poultry upper respiratory diseases and a preparation method thereof, belonging to the field of animal husbandry and veterinary medicine. A traditional Chinese medicine aerosol for treating poultry upper respiratory diseases. The raw materials are calculated in parts by weight: 2 parts of Ligusticum edulis, 1 part of tangerine peel, 0.5-1 part of mint, 0.5-1 part of asarum, 0.5 part of dried ginger, and 2.5-1 part of ethanol 3 parts, 1.5 to 2 parts of dimethyl ether. The invention is used for treating poultry upper respiratory diseases, has excellent curative effect, good atomization effect, spray rate not lower than 1.3g / s, and is convenient for intensive breeding and administration.

The invention discloses a plant residue composition with anti-inflammatory effect and application thereof. The plant residue composition disclosed by the invention is composed of the following components by mass percent: 0.6-3.4% of safflower extraction residue, 0.5-4.1% of hawthorn extraction residue and 0.3-2.7% of panax notoginseng extraction residue. The plant residue composition has the effects of balancing oil secretion, inhibiting bacteria, diminishing inflammation and relieving itching when being applied to body wash.