The invention provides novel artificial tussah silk fibers and a manufacturing method of the novel artificial tussah silk fibers. The novel artificial tussah silk fibers are prepared by fusing and spinning modified polyester, wherein the modified polyester is prepared from the following components in parts by weight: terephthalic acid, ethylene glycol, ethyleneglycol m-phthalate-5-sodium sulfonate, polyethylene glycol, monopentaerythritol, diethylene glycol, an antistatic agent, an antioxidant and a stabilizer. The artificial tussah silk fibers are processed through a chemical and physical modification method, and one type of novel fiber materials capable of replacing natural tussah silk fibers can be developed; the characteristics of natural slight yellow color and luster, jewelry-like color and luster, and rough appearance and style of the artificial tussah silk fibers, the natural tussah silk fibers and fabrics are kept; the defects of common disadvantages of the artificial fibers and the natural tussah silk fibers are also overcome; comprehensive properties including humidity absorption and breathability, antistatic property, anti-pilling, softness and bulkiness, soft color and luster, stiffness and smoothness and uneasiness of deformation and the like are better than those of the natural tussah silk fibers.