31 results about "Pseudoephedrine HCl" patented technology

The invention relates to anti-coronavirus traditional Chinese medicine granules and a preparation method and application thereof. The anti-coronavirus traditional Chinese medicine granules comprise atraditional Chinese medicine active extract composed of separately extracted first extract and second extract, wherein the first extract is a water or alcohol-water extract of herba ephedrae, semen armeniacae amarum, gypsum fibrosum, semen coicis, rhizoma atractylodis, herba pogostemonis, rhizoma polygoni cuspidati, herba verbenae, rhizoma phragmitis, semen lepidii, exocarpium citri grandis and herba artemisiae annuae; the second extract is a water or alcohol-water extract of radix glycyrrhizae; and each 10 g of granules contain not less than 2.3 mg of ephedrine hydrochloride and pseudoephedrine hydrochloride, not less than 42.7 mg of naringin and not less than 7.7 mg of glycyrrhizic acid. The traditional Chinese medicine granules provided by the invention can be used for treating a coronavirus disease.

The invention discloses a compound rupatadine bioadhesion nasal gel product and a preparation method. The compound rupatadine bioadhesion nasal gel product is characterized by being prepared from, 10-100 parts of rupatadine and salts thereof, 5-20 parts of xylometazoline hydrochloride / naphazoline / pseudoephedrine hydrochloride, 1-4 parts of furacilin, 300-5000 parts of polymer gel materials, 2-200 parts of a biological adhesive, 180-200 parts of a buffer salt, 800-1600 parts of a wetting agent and 20000 parts of sterile water for injection. The wetting agent is dissolved into 2 / 3 of the sterile water for injection to obtain a solution A; the polymer gel material is stirred and added into the solution A to obtain a gel system B; the biological adhesive is dispersed into the gel system B to obtain a gel system C; the rupatadine and salts thereof, the xylometazoline hydrochloride / naphazoline / pseudoephedrine hydrochloride, the furacilin and the buffer salt are successively added into 1 / 3 of the sterile water for injection, and sonication is performed to obtain a solution D; the solution D is dispersed into the gel system C, and stirring is performed to obtain the final product.

The invention discloses a quality detection method of a five-flavor manna medicine bath preparation. The five-flavor manna medicine bath preparation is made from raw materials of Juniperus formosana, ephedra, rhododendron anthopogonoide, myricaria and artemisia sieversiana according to a conventional method of pharmaceutics. On the basis of the primary standard, the thin layer chromatography of ephedra and rhododendron anthopogonoide is revised, the thin layer chromatography of Juniperus formosana and artemisia sieversiana is added. Under the simple and convenient condition of mobile phase, octyl silane bonding silica gel or phenyl bonding silica gel is used as filler, and simultaneously, the contents of ephedrine hydrochloride and pseudoephedrine hydrochloride in the ephedra are detected. The invention also provides a method for measuring the content of hyperoside in five-flavor manna preparation rhododendron anthopogonoide, thus ensuring the safety, effectiveness and controllability of product quality. By the quality detection method, the quality standard of the existing five-flavor manna medicine bath preparation is improved correspondingly.

The invention provides a compound desloratadine / pseudoephedrine (abbreviated as compound dichloropseudoephedrine) slow-release pellets and a preparation method thereof. The preparation of the compound dichloropseudoephedrine sustained-release pellets of the present invention is to adopt the extrusion spheronization method to prepare the pellet cores containing pseudoephedrine hydrochloride, and then utilize hot-melt coating technology to coat the pellet cores with slow-release layers and desloratadine-containing pellets in sequence. It is prepared as an immediate-release layer, and the coating material does not need to use any solvent. The composition of the lipid material and the hydrophilic polymer with surface activity involved in the present invention uses the hot-melt coating technology to prepare the compound dichloropseudoelphus slow-release pellets, which can not only make full use of the hot-melt coating technology, but also has the advantages of safety, environmental protection and energy saving. , high efficiency, can improve the advantages of drug stability and bioavailability, and can release the two drugs on demand and completely, the release curve is consistent with the reference preparation, and can be produced on a large scale.