The present invention discloses a food supplement with combination of astaxanthin and omega-3. The food supplement is characterized in that the components of the food supplement comprise haematococcus pluvialis powder, perilla seed powder, flax seed powder, schizochytrium limacinum powder and coralline algae powder. The combination of astaxanthin and omega-3 is capable of balancing human immune functions efficiently, enhancing the capability of the body against antiviral infection, inhibiting cancer cell proliferation, curing body injuries rapidly and eliminating vivotoxin. Meanwhile, the growth of bodies, especially bodies of children, is promoted and the physical quality get enhanced. The immune system is enhanced, and the blood circulation of the brain and the whole body is improved. The rise of the blood pressure and blood sugar is suppressed, the brain health is promoted, the cell vitality is improved, the serum cholesterol level is lowered, and the risk of tumor incidence is lowed.