3 results about "Sulfur monochloride" patented technology

The application belongs to the technical field of rubber additive synthesis, and particularly relates to a method for continuously preparing 4,4'-dithiodimorpholine. The method uses sulfur monochloride, morpholine, 32wt% liquid alkali (sodium hydroxide solution) and 120# solvent oil as raw materials, and generates 4,4'-dithiodimorpholine in a dynamic tubular reactor. After the reaction is completed, the material flowing out of the dynamic tubular reactor is collected, and the product is obtained through static layering, washing, filtering and drying. The method uses the dynamic tubular reactor for reaction, and the mass transfer and heat transfer efficiency are extremely high. The material is instantaneously and uniformly mixed, so that the morpholine and the sulfur monochloride are rapidly contacted and reacted, the reaction heat can be instantaneously removed, the optimal reaction temperature can be accurately maintained, the continuous production can be realized, the production capacity is greatly improved, the reaction time of the traditional kettle reactor is shortened from 2-7h to 10min, the raw material conversion rate is as high as 99% or more, and the goals of cost reduction and efficiency improvement, green safety are finally achieved.

This invention provides a fully continuous preparation method for probucol active pharmaceutical ingredient intermediates, belonging to the field of organic synthesis technology. The method includes the following steps: a mixed solution of 2,6-di-tert-butylphenol and elemental iodine, and a sulfur monochloride solution are continuously passed into a microchannel reactor for a condensation reaction, followed by cooling of the reaction solution; then, the solution is continuously passed into a fixed-bed reactor for hydrogenation under the catalysis of sulfur-modified Ni-Co / Al2O3. This invention combines a microchannel continuous flow reactor and a fixed-bed reactor for the continuous synthesis of probucol active pharmaceutical ingredient intermediates. The process steps and operations are simple, reducing intermediate purification steps and shortening the processing time; the solvent has low toxicity, making the method green, safe, and environmentally friendly; the raw materials are inexpensive and readily available, the reaction conditions are mild, and the target product has high yield and purity, resulting in good product quality; the use of the microchannel continuous flow reactor improves the mass and heat transfer of materials, reduces the amount of excipients, and further reduces production costs.

This invention provides a method for hydrolyzing sulfur monochloride, relating to the field of sulfur monochloride treatment technology. The method includes: adding water by adding 1.5 cubic meters of room-temperature clean water to the interior of a 3-cubic-meter reactor body; adding sulfur monochloride through a feeding mechanism; stirring by activating a stirring mechanism inside the top cover; heating by maintaining stirring for one hour after adding the material, and introducing steam into the reactor jacket to raise the temperature inside the reactor to above 100°C until hydrolysis is complete; and by setting a feeding mechanism inside the top cover, when the pressure inside the reactor body becomes too high, a piston is pushed upwards, causing the connecting strip on the outer surface of the piston to slide inside the spiral groove, causing the first feeding pipe to rotate until the piston rises to the top, completely displacing the first and second feeding holes, thereby stopping the addition of sulfur monochloride to prevent incomplete reaction of the sulfur monochloride.