138results about How to "Guaranteed detection sensitivity" patented technology

The embodiment of the invention discloses an array substrate, a preparation method thereof, a display panel and a display device. The array substrate comprises a first underlayer substrate, a fingerprint identification unit, a driving circuit layer and a transparent film layer, and is characterized in that the fingerprint identification unit comprises a photosensitive diode, and the fingerprint identification unit is used for performing fingerprint identification according to light reflected to the fingerprint identification unit via a touch main body; the driving circuit layer is located at the side, which is away from the fingerprint identification unit, of the first underlayer substrate, at least one opening structure is formed in the driving circuit layer and the first underlayer substrate, and the vertical projection of the opening structure on the first underlayer substrate and the vertical projection of the photosensitive diode on the first underlayer substrate have an overlapping area; and the transparent film layer at least fills the opening structure. According to the invention, the photosensitive diode is provided with the transparent film layer above, so that the transmittance of the film layer above the photosensitive diode is improved, the fingerprint identification unit can well receive the light reflected to the fingerprint identification unit via the touch main body, and the detection sensitivity of the fingerprint identification unit is ensured.

The invention relates to a flexible eddy current testing probe for a heat transfer pipe of a steam generator of a nuclear power plant. The flexible eddy current testing probe comprises a guide cone, a first petal, a first line groove cover, a skeleton, a coil coiled on the skeleton, a second line groove cover, a second petal, a lantern ring, a first connecting piece, a corrugated pipe, multiple centering rings sleeved on the corrugated pipe, a copper cap, a small-diameter nylon pipe, a second connecting piece and a large-diameter nylon pipe, wherein the guide cone, the first petal and the first line groove cover are connected in series through a first spring; the second line groove cover, the second petal and the lantern ring are connected in series through a second spring; the first connecting piece is fixedly connected with the corrugated pipe; the corrugated pipe is connected with the small-diameter nylon pipe through the copper cap; the small-diameter nylon pipe is docked with the large-diameter nylon pipe through the second connecting piece; the small-diameter nylon is sleeved with multiple beads, and a stainless steel ring is arranged between the beads; and the coil is connected with a cable. According to the invention, flexibility and elasticity of the probe are increased, and the eddy current testing of an elbow with small curvature radius is completed at one time quickly and effectively.

A discharge ionization current detector using a low-frequency barrier discharge is provided to improve the linearity of detection sensitivity with respect to a sample introduction amount. From a lower end of a lower gas passage 10 connected to a lower end of an upper gas passage 4, a dilution gas is supplied upward against a downward flow of a plasma gas. A gas discharge passage 15 for discharging a plasma gas, the dilution gas and a sample gas is arranged between an ion-collecting electrode 11 and a bias voltage application electrode 12. The sample gas introduced through a capillary tube 16 is mixed with the plasma gas and the dilution gas due to a disturbed flow generated by collision of the plasma gas and the dilution gas. The sample component is efficiently ionized by light from the plasma without undergoing light-shielding effect of concentrated sample components. Furthermore, since an ion generation area is close to the electrodes 11 and 12, ions can quickly move the short distance due to the action of a direct current electric field. Therefore, the ions can reach the ion-collecting electrode 11 before their lifetime terminates.

The invention provides a quasi-solid-state single line laser radar based on an MEMS-like galvanometer, and an operating method of the quasi-solid-state single line laser radar. The quasi-solid-state single line laser radar comprises a laser device, a detector and a galvanometer, wherein the galvanometer comprises a base, magnets, a coil, a reflector, a torsion bar and a fixing member; the magnets are arranged on two opposite sides of the base separately, and the polarities of the isolated magnets at opposite positions are opposite; two ends of the coil are connected with an alternating current; the reflector is connected with the coil; the reflector reflects detection light emitted by the laser device to a detected object, and the detection light on the detected object enters the detector after passing through the reflector; one end of the torsion bar is fixed on the base by means of the fixing member, and the other end is connected with the coil; and the coil generates torque in a magnetic field formed by the magnets under the driving of the alternating current, so as to drive the reflector to twist by taking the torsion bar as an axis. The quasi-solid-state single line laser radar has the advantages of simple structure, low cost and the like.

The invention discloses a nucleic acid nano-Au biosensor for detecting lead ions and a preparation method thereof. The nucleic acid nano-Au biosensor for detecting lead ions utilizes the principle that: when lead ions exist, the specific nuclease can cut the substrate which is complemented therewith, and utilizes the immune colloidal gold as an amplification color appearance system, and accordingly, the lead irons are quickly detected. The nucleic acid nano-Au biosensor for detecting lead ions has the advantages of high flexibility, low cost, no need of using any instrument and the like, not only the defect of requiring large-scale instruments in the former detection methods is solved, but also the detection flexibility can be ensured.

The invention discloses a kit for detecting a carbohydrate antigen as well as a detection method and an application thereof, and belongs to the technical field of in vitro diagnosis and detection. The kit consists of the following components: (1) a magnetic microsphere system: including magnetic microspheres in direct or indirect connection to an antibody 1 of the carbohydrate antigen; (2) a first marker system: including an antibody 2 in direct or indirect connection to carbohydrate antigen of a first marking tracker or a second marking tracer; and (3) a second marker system: including an antibody 2 in direct or indirect connection to carbohydrate antigen of a first marking tracker or a second marking tracer, wherein the antibody 1 of the carbohydrate antigen is different from the antibody 2 of the carbohydrate antigen in antibody site. The kit and the detection method disclosed by the invention, in detecting the carbohydrate antigen, have the advantages of being high in sensitivity and free from a HOOK effect.

The invention discloses an immune-fluorescence test strip component for rapidly detecting C-reactive protein quantitatively, a detection card component produced by the same and a method for preparing the same. The test strip component comprises a test strip and a platinum porphyrin marked specific antibody independently packed. The test strip comprises a bottom lining, a water absorption pad, coating analysis film and a sample pad. The coating analysis film is provided with a detection line and a quality control line, a specific antibody coated by the detection line is a C-reactive protein resistance monoclonal antibody, and a specific antibody coated by the quality control line is a rabbit intravenous gamma globulin (IgG) antibody; the detection card component comprises a test strip, a card box composed of a cover plate and a back plate and a latinum porphyrin marked specific antibody independently packed. The test strip component for detecting C-reactive protein in body fluid has the advantages of being simple in operation, rapid, sensitive, good in specificity and the like, and having good clinical application prospect.

The invention relates to a nucleic acid nano-gold biosensor for detecting mercury ions and a corresponding kit. The nucleic acid nano-gold biosensor comprises a sample pad, a gold-labeled pad, a nitrocellulose membrane and a water-absorbing pad, wherein the nitrocellulose membrane is provided with a detection line and a quality control line; colloidal gold is sprayed on the gold-labeled pad; the detection line is marked on the nitrocellulose membrane after streptavidin and a biotin-labeled SEQ ID NO:3 sequence react; the quality control line is marked on the nitrocellulose membrane after streptavidin and a biotin-labeled SEQ ID NO:4 sequence react; colloidal gold is bonded to an SEQ ID NO:2 sequence, and 5'-terminal of the sequence is modified by sulfydryl. According to the nucleic acid nano-gold biosensor and the corresponding kit, the mercury ions are detected rapidly, simply, conveniently and directly, the defect that a large instrument is required in the conventional detection method is overcome, and the detection sensitivity can be guaranteed.

The invention discloses line eliminating method immunochromatography test paper and application thereof in a CRISPR nucleic acid test. A kit provided by the invention comprises: 1) immunochromatography test paper; and 2) a CRISPR reaction system, wherein in a sample flow direction of the immunochromatography test paper sequentially comprises a sample pad containing a colloidal gold labelled antibody, an NC membrane contain a T line and a C line and water-absorbent filter paper; the T line is formed by streptavidin; the C line is formed by a secondary antibody of the colloidal gold labelled antibody; the CRISPR reaction system comprises report RNA, crRNA and Cas protein; and the Cas protein is in a second-class type V or type VI CRISPR system. Experiments of the invention prove that the test paper in the kit can realize high-sensitivity, high-specificity and convenient detection of multiple specific nucleic acids (pathogens, gene mutation and drug-resistant mutation) by binding a CRISPRnucleic acid detection system.

The invention provides a method for preparing a solid enzyme reagent which is used to fast measure the organophosphorus and carbamate toxicity of pesticide residue and its using method. The agent is formed by choline esterase, buffer solution and carrier. The solid enzyme reagent can be stored at indoor temperature above 20 days.

The invention relates to a 2mum coherent wind lidar polarization state matching and correcting system, which comprises a 2mum laser, a first single-mode polarization-maintaining fiber, an acoustooptic frequency shifter, a second single-mode polarization-maintaining fiber, a tail fiber-type Grin lens, a lambda / 2 wave plate, a lens, a polarization beam splitter prism, a lambda / 4 wave plate, an off-axis optical antenna, a stepper motor drive device, a polarizer, a first tail fiber-type coupling lends, a double-channel polarization state analyzer system, a second fiber beam splitter, a photodiode, a coaxial cable, and an oscilloscope. The system can monitor each polarization state situation of reference local oscillation laser signals and laser echo signals in the coherent wind lidar system in real time. when polarization state of two light beams are not matched, the double-channel polarization state analyzer system can automatically correct the polarization state of the laser until matching is realized, thereby greatly improving the heterodyne efficiency of the coherent wind lidar system and improvising detection sensitivity of the system.

The invention relates to an on-line detection method of free chlorine during the synthesis process of hydrogen chloride, which comprises the following steps: (1) leading the hydrogen chloride which isled out of a main pipe of the hydrogen chloride to sequentially pass thorough a three-way valve and a flowmeter for metering, then leading the hydrogen chloride to enter into an absorber, leading pure water to enter into the absorber after passing through the flowmeter, and preparing dilute hydrochloric acid solution with the weight concentration of 0.1-10% in the absorber; (2) overflowing the dilute hydrochloric acid solution in the absorber for passing through an ORP meter for carrying out detection, wherein, the free chlorine in hydrogen chloride gas leads the ORP value to change; and (3)transferring information of the changed ORP value to a DCS control center, when the ORP value is not less than 500mv, the DSC control center can automatically regulate an automatic valve of chlorine or hydrogen according to the mix ratio difference of the chlorine or the hydrogen which enters into a furnace and reduce the flow rate of the chlorine or increase the flow rate of the hydrogen. The method reduces the work intensity, ensures the detection sensitivity and is conductive to stable production.

The invention discloses a probe mechanism of an oil and gas pipeline crack detector. The probe mechanism of the oil and gas pipeline crack detector comprises a signal excitating and acquiring mechanism, wherein a spring connecting rod supporting mechanism and a spring slide block supporting mechanism are connected at the front end and the back end of the signal excitating and acquiring mechanism through universal rotating mechanisms respectively; the spring connecting rod supporting mechanism and the spring slide block supporting mechanism are fixedly arranged on a framework of the crack detector; the signal excitating and acquiring mechanism comprises a long arm-shaped connecting base body; transversely arranged supporting wheels are pivoted on the upper parts of the front end and the back end of the connecting base body; an iron core is arranged on the connecting base body; a probe shell assembly is arranged above the iron core and on the middle part of the connecting base body; the front part and the back part of the probe shell assembly are pivoted on the iron core through a front probe arm and a back probe arm respectively; an exciting circuit assembly fixed on the iron core is arranged below the probe shell assembly; magnets are arranged between the probe shell assembly and the front and back supporting wheels respectively; and steel brushes are arranged above the magnets. The probe mechanism of the oil and gas pipeline crack detector is always tightly adhered to the inner wall of a pipeline while passing through a welding seam of the pipeline, so that the detection precision and the sensitivity of the detector can be improved.

The invention provides an electrically actuated steering lock device which can realizes assembly of a substrate with fewer parts and good workability and without looseness. The electrically actuated steering lock device (1) comprises a locking member, an electric motor driving the locking member to work, a driving mechanism converting a rotation force of an output shaft of the electric motor to an advancing and retreating force of the locking member, a magnet fixed to the locking member, a substrate (15) provided with a magnetic force detection element capable of detecting a magnetic force of the magnet and disposed opposite to the magnetic, and a housing (2) formed by a shell (3) receiving the locking member, the electric motor, the magnet and the substrate (15) and a cover plate (4) sealing an open part of the shell (3). The inside of the shell (3) is provided with a substrate receiving part (3B) for receiving the substrate (15); a locating member (21) disposed on the substrate (15) is provided with a snug (21c) capable of being pressed flat; and the cover plate (4) is provided with a substrate pressing part (4a) capable of pressing the snug (21c) of the locating member (21) flat.

The invention provides a method for separating and detecting harmful phenols in main stream smoke of cigarettes to overcome the drawback of the prior art that a high efficiency liquid chromatography can only measure the mixed content of m-cresol and p-cresol when used to detect the harmful phenols in the main stream smoke of the cigarettes by adding a certain amount of beta-cyclodextrin in a flowing phase of the high efficiency liquid chromatography. Thus, while successfully separating and detecting isomers of the m-cresol and the p-cresol, the method avoids influencing the separation and measurement of the content of o-dihydroxybenzene, m-dihydroxybenzene, p-dihydroxybenzene, phenol and o-cresol. The method is expected to be applied to daily detection of harmful phenol substances of cigarette products.

The invention discloses an air detection device with a telescopic and storable probe. The device comprises a mounting base, a probe and a telescopic base, a telescopic groove is formed in the middle in the mounting base, and the telescopic base is located at the upper end in the telescopic groove. The telescopic seat is slidably connected with the telescopic groove; the probe is of a cylindrical structure, the probe is transversely placed in the upper end surface of the telescopic seat, and two ends of the probe are rotationally connected with the telescopic seat through small shafts. The beneficial effects are that: a telescopic motor works to drive a threaded rod to rotate, the threaded rod is in threaded connection with a threaded sleeve, the telescopic base can move in the direction ofthe telescopic groove, the probe can be accommodated in the telescopic groove, a sliding door is arranged, the sliding door is automatically closed under the action of a spring, dust in the air is prevented from entering the telescopic groove, the probe is subjected to dustproof protection, the probe can be driven to rotate through work of a rotating motor, a wiping cotton layer can wipe a detection area of the probe when the probe rotates, dust adhering to the surface of the probe is removed, and the detection sensitivity of the probe is guaranteed.

The invention discloses a near-infrared laser confocal biochip scanner. The near-infrared laser confocal biochip scanner comprises an optical module, wherein the optical module comprises a near-infrared laser and a laser cofocal detection system; the laser cofocal detection system comprises a collimator lens, a laser filter, a dichroscope, an objective lens, a fluorescence filter, a convergent lens, a pinhole diaphragm and a photoelectric detector; laser emitted by the near-infrared laser passes through the collimator lens to form parallel light; the parallel light passes through the laser filter, is reflected by the dichroscope and then can be focused on the surface of a biochip through the objective lens; fluorescent light emitted by exciting the biochip becomes the parallel light through the objective lens; the parallel light sequentially passes through the dichroscope and the convergent lens and is focused on the pinhole diaphragm; and the photoelectric detector is placed adjacentto a pinhole and can input a signal into an electrical control module. According to the near-infrared laser confocal biochip scanner disclosed by the invention, the scanning range of a to-be-detectedand scanned biological sample can be effectively improved; meanwhile, detection precision and sensitivity are ensured; in addition, the near-infrared laser confocal biochip scanner is simple in structure, easy to operate and low in manufacturing cost.

The present invention discloses a high-sensitivity optical fiber temperature sensing probe and a manufacturing method thereof. A probe body is internally provided with a confined space, the side wallof the confined space is provided with incident and emergent window, the confined space comprises a first tube cavity and a second tube cavity which communicate in a direction far away from the incident and emergent window in order, and the first tube cavity is filled with a volatile liquid. Through adoption of the high-sensitivity optical fiber temperature sensing probe with optimal design, the confined space is filled with the volatile liquid, the temperature sensing expanding features of the volatile liquid are employed, the refractive index of the volatile liquid is changed with the changeof the environment temperature to achieve flexible modulation of the refractive index and temperature sensing of the incident liquid surface so as to achieve low-cost temperature sensitive detection.The present invention further discloses a manufacturing method of a high-sensitivity optical fiber temperature sensing probe.

The invention relates to a cigarette formula quality trend analysis method based on volatile characteristic components in cut tobacco. The method includes the following steps that 1, samples are prepared; 2, the samples are pretreated; 3, the samples are treated and detected, wherein HS-GC / MS is adopted for analysis; 4, according to the contents of non-volatile characteristic components in different batches, the principal component analysis-Mahalanobis distance is adopted to study the quality trend change of the samples, and similarity analysis of the different samples is conducted. By means of the method, the contents of the volatile characteristic components in the cigarette cut tobacco can be directly acquired, principal components in the components are obtained, score vectors of the principal components are used for two-dimensional or three-dimensional spectrum recognition, the spectrum is displayed through a computer and chemometrics method, and classification of the different samples is achieved. The cigarette product formula quality monitoring method is stable and objective; no contamination is generated; on the premise of guaranteeing detection accuracy and sensitivity, detection cost is lowered, and detection time is shortened.

The invention provides a method for determining rivaroxaban and related substances thereof by using high performance liquid chromatography, wherein the high performance liquid chromatography comprisesthe following conditions that a stationary phase is octadecylsilane chemically bonded silica,a mobile phase A is selected from a phosphate buffer solution of which the pH value is 5.0-7.0, a citratebuffer solution, an acetate buffer solution or a carbonate buffer solution, a mobile phase B is acetonitrile or methanol, and gradient elution is carried out. The method has the characteristics of good specificity, high sensitivity, good reproducibility, simple post-data processing and the like, especially can solve the problems of interference of a blank solvent, peak pattern difference of individual impurity peaks, low separation degree and the like, and can obtain all contents and related substance analysis results by one-time sample injection.

The invention discloses a cell signal pathway detection kit and a detection method based on a mass spectrum flow technology. Through the kit and a matched signal pathway stimulant and a detection antibody, and by utilizing a mass spectrum flow detection technology, an intracellular signal path activation level can be specifically and effectively detected at a high throughput and a single cell level, the sample detection precision is greatly improved, and a false negative analysis result possibly existing in a traditional detection means is avoided to a great extent.

The invention relates to a recombinant vector and in particular relates to a recombinant vector used for biologically detecting dioxin substances and a cell containing the recombinant vector. The invention also relates to an application of the recombinant vector and the cell to biological detection of the dioxin substances.

The invention discloses a double-chamber high-voltage soft bag detector. A detection channel device is arranged on a frame; a feeding mesh belt is arranged at the feeding end of the detection channeldevice, and an output mesh belt is arranged at the discharge end; a waste removing device is arranged above the output mesh belt; the detection channel device comprises a wavy soft bag conveying beltformed by connecting a plurality of power rollers side by side through a connecting belt; a bag head detection device and a bag body detection device are arranged on a detection station of the soft bag conveying belt; the bag body detection device comprises a bag body front side detection device and a bag body back side detection device; the bag body detection device is arranged at the inclined plane position of the soft bag conveying belt, and the inclined plane is formed by connecting at least two power rollers through the connecting belt. and a bag tail clamping device is arranged above thesoft bag conveying belt. The detection stability can be improved, ridge type conveying is adopted, and the detection sensitivity is improved; detection electrodes are arranged in a crossed covering manner to reduce false detection; and the detection electrodes can be automatically adjusted according to the bag body contour, and the leakage point capture sensitivity is improved.

The invention discloses an OTFT ammonia gas sensor embedded with a small molecule additive and a preparation method of the OTFT ammonia gas sensor. When the small molecule additive is arranged in an organic semi-conductor layer, a solution continuous processing method or a solid-state diffusion method is adopted, and therefore the OTFT ammonia gas sensor embedded with the small molecule additive at least containing one cyano group or fluoro group is obtained, wherein the solution continuous processing method is used for spin-coating or dip-coating the surface of the prepared organic semi-conductor film with an orthogonal solution containing the small molecule additive, and the solid-state diffusion method is used for coating the surface of the prepared organic semi-conductor film with thesmall molecule additive material through vacuum thermal evaporation. According to the OTFT ammonia gas sensor, the problem that an existing OTFT ammonia gas sensor is poor in stability is solved whilethe high sensitivity of the OTFT ammonia gas sensor is guaranteed.

The invention relates to a synchronous light signal demodulation technology and particularly relates to a gas detection method and device based on a local light signal demodulation and modulation technology. The gas detection method comprises the following steps: (a) dividing laser, which is subjected to wavelength modulation and is output by a semiconductor laser device, into two beams; (b) inputting one beam of light as detection light into a sensing head for gas detection and inputting a signal carrying information of gas to be detected into a lock-in amplifier; (c) converting the other beam of light into a corresponding electric signal, filtering to remove noises, amplifying, locking, and transmitting the electric signal to a synchronous end of the lock-in amplifier; and (d) analyzing the signal, which is synchronously demodulated by the lock-in amplifier, to obtain concentration information of the gas to be detected. According to the gas detection method and device, a synchronous signal is extracted at a detection system end and the advantage of long-distance transmission of light signals in an optical fiber is utilized so as to avoid the disadvantages of great loss, high cost and the like generated when electric signals are transmitted in a long distance.

The invention which relates to the technical field of detection discloses a carbon monoxide detector. The carbon monoxide detector comprises a gas sensitive resistor, and an induction thread of the gas sensitive resistor comprises 15% of a mixed metal salt catalyst which comprises 70% of Pt, 25% of Au and 5% of Ag. According to the invention, the carbon monoxide detector which is improved has thecharacteristics of satisfication of the operation environment of voltage testers, low power consumption and small volume, so the combination of the carbon monoxide detector and the voltage test pencil becomes possible. The invention also provides the voltage test pencil which integrates the carbon monoxide detector provided in the invention, and the voltage test pencil which can be integrated with an illumination module can be applied to the voltage test work of dangerous areas. Compared with present voltage test pencils, the voltage test pencil of the invention can be used when light in the work area is not clear, so the electric shock danger of workers is prevented; and the worker can be timely promoted to rapidly depart to guarantee the safety when carbon monoxide which has a standard-exceeded concentration may initiate the explosion danger and the positioning danger once carbon monoxide encounters electric sparks.

The invention discloses a device and a method for measuring a phase delay temperature characteristic of an optical fiber quarter wave plate, and belongs to the technical field of optical fiber current transformers. The device comprises a broad spectrum optical source, a polarizer, a quarter wave plate and a polarization beam splitter, wherein one end of the quarter wave plate is in direct-axis welding connection with output tail fibers of the polarizer at an angle alpha in a welding way, and the other end of the quarter wave plate is in direct-axis welding connection with input tail fibers of the polarization beam splitter at an angle beta. According to the method, light emitted from the broad spectrum optical source is polarized into linearly polarized light through the polarizer, the linearly polarized light is split into two beams of orthogonal linearly polarized light through the quarter wave plate, each of the two beams of linearly polarized light is split into two orthogonal linearly polarized light at the input tail fibers of the polarization beam splitter, two beams of linearly polarized light are interfered at a fast axis, two beams of linearly polarized light are interfered at a slow axis, and the phase delay of the quarter wave plate is solved by measuring the interference light intensity of the two output tail fibers of the polarization beam splitter. According to the device and the method, a more accurate phase delay temperature characteristic model for the optical fiber quarter wave plate can be established according to experimental data, and the test accuracy of an optical fiber current transformer can be improved.

The invention discloses a detection mechanism for a wagon leaning plate of a wagon dumper, which comprises a pressing rod, a rotating shaft, a signal rod and a reset unit. A groove is formed in a pressing surface of the main body of the wagon leaning plate; the pressing rod and the rotating shaft are contained in the groove; the rotating shaft is rotationally installed on the main body; the pressing rod is connected with the inner side of the rotating shaft; the signal rod is connected with the outer side of the rotating shaft; when the pressing rod is not conducted to the pressure effect of a railway wagon to be dumped by the wagon dumper, the signal rod is positioned in an initial position; when the pressing rod is conducted to the pressure effect of the railway wagon, the signal rod is positioned in pressing position; a sensor is used for detecting the position of the signal rod, so as to give signals to show whether the wagon leaning plate is leaned; and the reset unit is used for resetting the signal rod to the initial position from the pressing position. The invention also discloses the wagon leaning plate and the wagon dumper. The detection mechanism has high detection precision, and can not produce error signals, so as to be capable of ensuring that the wagon leaning plate leans closely against the railway wagon, and to prevent the occurrence of rail falling off accidents.

The invention relates to a method and probe sequence for detecting FGFRs gene mutation based on high-throughput sequencing. The method comprises the following steps of 1) co-extracting genome DNA andtotal RNA of a sample; 2) fragmenting the genome DNA and recovering the fragmented DNA; 3) performing total RNA interruption and / or primer hybridization according to the total RNA quality control condition; 3) synthesizing a first strand of cDNA; 4) synthesizing a second strand of the cDNA; 5) mixing the fragmented DNA with the cDNA to construct a mixed library; 6) performing hybridization and capture by adopting a capture probe; 7) performing library amplification and purification after capture; and 8) performing high-throughput sequencing and mutation analysis. According to the invention, single base mutation, insertion and deletion mutation, fusion mutation and relative expression quantity analysis of FGFR1, FGFR2, FGFR3 and FGFR4 genes can be detected.

The invention relates to non-destructive detecting system for aluminum alloy, and in particular to a water immersion type ultrasonic detecting system for aluminum alloy flat casting ingots and a usingmethod thereof. The system comprises: an ultrasonic water tank (1), a movable support frame (2), a water immersion type phased array ultrasonic probe (4), bubble brushes (5), a Z-direction movement axis (6), a Y-direction track (7), a scanning bridge and electrical system (8), a probe cable (9), a phased array ultrasonoscope (10), X-axis tracks (11), an industrial computer (13) and a test block bracket (15). Through the system disclosed by the invention, differentiated, highly repeatable and highly reproducible water immersion type phased array solutions are established for different types ofaluminum alloy defects.