The invention relates to a seamless self-protection flux-cored wire for low-nitrogen non-magnetic naval vessel steel welding. According to the technical scheme, the seamless self-protection flux-coredwire is composed of 70 wt%-80 wt% of a stainless steel strip and 20 wt%-30 wt% of flux-cored powder, and the stainless steel strip is filled with the flux-cored powder. The stainless steel strip comprises the following chemical components of, in percentage by weight, 0.03-0.08 wt% of C, less than or equal to 1wt% of Si, less than or equal to 2 wt% of Mn, 18-20 wt% of Cr, 8-11 wt% of Ni, less thanor equal to 0.03 wt% of S, less than or equal to 0.03 wt% of P and the balance Fe and inevitable impurities. The flux-cored powder comprises the following chemical components of, in percentage by weight, 40-43 wt% of barium fluoride, 5-8 wt% of marble, 8-10 wt% of aluminum powder, 2-4 wt% of silicon powder, 7-10 wt% of manganese powder, 2-5 wt% of manganese nitride, 10-13 wt% of nickel powder, 5-7 wt% of chromium powder and the balance iron powder. According to the seamless self-protection flux-cored wire, weld metal formed by welding the low-nitrogen non-magnetic naval vessel steel is high in strength, good in ductility and toughness, non-magnetic and excellent in seawater corrosion resistance.