29results about How to "Reliable detection method" patented technology

The invention discloses a DNA methylation biomarker combination for prostate cancer detection and application of the DNA methylation biomarker combination, and belongs to the technical field of biological medicine. The DNA methylation biomarker combination comprises a combination of methylation sites indicated by CG in the SEQ ID NO: 1 sequence of the USP44 gene and the SEQ ID NO: 2 sequence of the HIF3A gene. It is reported for the first time that the methylation levels of the USP44 gene and the HIF3A gene are detected at the same time to conduct auxiliary diagnosis on the prostatic cancer, a sample urine detection result shows that the sensitivity is 97.14%, the specificity is 97.78%, and the non-invasive and reliable prostatic cancer detection method is provided and has good application prospects in early screening of the prostatic cancer.

The present invention discloses a method for predicting rosin properties based on infrared spectroscopy, the method comprising: S1, collecting rosin samples from wetland pine wood, dividing the rosin samples into a first rosin sample and a second rosin sample; S2, analyzing the sample components based on the first rosin sample to obtain the rosin components; S3, collecting near-infrared spectral data of the sample based on the second rosin sample to obtain near-infrared spectral data of the rosin; S4, correlating and fitting the rosin components with the near-infrared spectral data to establish a near-infrared correction model for rosin properties; S5, using an external validation set of rosin samples that do not participate in modeling to verify the near-infrared correction model for rosin properties; S6, predicting rosin properties based on the near-infrared correction model for rosin properties to obtain a rosin property prediction result. The present invention improves the efficiency of genetic improvement of resin-producing tree species and promotes the rapid development of forest genetic improvement research.

The invention discloses a method for detecting the air tightness of a plate-fin heat exchanger, and provides a method for detecting whether a leakage point exists in the heat exchanger through secondary negative pressure, which comprises the following steps of: forming a closed inner cavity in the plate-fin heat exchanger, then vacuumizing the inner cavity of the plate-fin heat exchanger, stopping vacuumizing when the inner cavity reaches a preset primary negative pressure value, and stopping vacuumizing when the inner cavity reaches the preset primary negative pressure value. The negative pressure change of the inner cavity is observed, and if the first-stage negative pressure value of the inner cavity is not kept unchanged after a period of time, it is judged that serious leakage points exist in the plate-fin heat exchanger, and the air tightness is unqualified; and if the first-stage negative pressure value of the inner cavity is kept unchanged after a period of time, the inner cavity of the plate-fin heat exchanger continues to be vacuumized, and when the inner cavity reaches the preset second-stage negative pressure value and can be kept for a certain period of time, it is judged that the air tightness of the plate-fin heat exchanger is qualified. The air tightness detection of the plate-fin heat exchanger can be quickly and efficiently completed, a drying step in a pressure water detection method is avoided, the limitation of the size of the detected heat exchanger by the size of a water tank is overcome, the detection environment is improved, and the detection efficiency is remarkably improved.

The invention provides an aging biomarker detection system and application thereof, and belongs to the technical field of biomedicine. The senescence biomarker detection system comprises senescence biomarker detection and senescence evaluation model establishment, has the characteristics of comprehensiveness, accuracy and high efficiency, and can provide powerful support for senescence research and anti-senescence intervention. The construction method of the senescence biomarker detection system is scientific and reasonable, the screened 12 senescence biomarkers have high specificity and sensitivity, the senescence degree is comprehensively evaluated through the integral senescence evaluation model, and the senescence biomarker detection system is comprehensive, accurate and efficient. The senescence biomarker detection system is wide in application, can be applied to multiple fields of senescence degree evaluation, disease risk prediction, anti-senescence intervention effect evaluation, drug research, development and screening and the like, provides a new tool and method for anti-senescence research and clinical practice, and has important application value and wide market prospects.

The utility model discloses an automatic tea basket lifting mechanism which comprises a lifting pipe, a driving motor and a tea basket arranged on the lifting pipe in a sleeved mode, a lead screw and a nut arranged on the lead screw in a sleeved mode are arranged in the lifting pipe, the driving motor is connected with the driving lead screw, a driving magnet is arranged on the nut, and a driven magnet corresponding to the nut is arranged on the tea basket. The tea basket and the nut are attracted and matched on the outer wall of the lifting pipe through the driving magnet and the driven magnet; an induction plate parallel to the lead screw is further arranged in the lifting pipe, an induction contact piece corresponding to the induction plate is arranged on the nut, and the induction contact piece reciprocates on the induction plate along with the nut and generates an induction signal for detecting the position of the tea basket on the lifting pipe. The upper end of the screw rod is freely arranged, screw rod clamping failure caused by three-point fixing of the screw rod is avoided, in addition, the sensing plate arranged in the length direction of the screw rod is matched with the sensing contact piece synchronously moving on the nut, the position of the tea strainer on the lifting pipe can be recognized and confirmed through sensing signals, and stability and reliability are achieved.

The invention provides a codominant SSR (simple sequence repeat) marker closely linked with a tobacco scopoletin gene qSco and an application method of the codominant SSR marker. The serial numbers of the codominant SSR marker closely linked with the tobacco scopoletin gene qSco are TM34422 and IDYK06329, and the nucleotide sequences of PCR (Polymerase Chain Reaction) amplification products of the codominant SSR marker closely linked with the tobacco scopoletin gene qSco are respectively shown as SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 and SEQ ID No. 4. The application is the application of the codominant SSR marker closely linked with the tobacco scopoletin gene qSco in detecting whether the tobacco scopoletin gene qSco exists in tobacco genome DNA (Deoxyribonucleic Acid) or not. Compared with a method in the prior art, the codominant SSR marker has the characteristics of accuracy, high efficiency, stability, convenience, low cost and no detection opportunity limitation, so that the molecular marker can be applied to auxiliary selection of the scopoletin gene qSco molecular marker in tobacco breeding.

The invention discloses an insulating sleeve feeding detection device and a test method thereof.The detection device comprises a feeding module, a conveying module and a detection module, a sleeve is initially fed through the feeding module, then conveyed to the detection module through the conveying module to be detected and then conveyed to the next working procedure through the conveying module, and the feeding module and the conveying module are sequentially arranged at intervals; the detection module is installed in the middle of the conveying module. Position judgment and fixed-length calculation can be carried out on the defects, the graduated scales are arranged on the two sides of the detection device, the length of the adjacent defect parts can be accurately calculated, the cutting frequency is determined according to the interval length, two defects with the long interval are cut separately, and material waste is avoided.

The invention provides a method for detecting the content of impurities in a tolvaptan sodium phosphate freeze-dried powder injection, which comprises the following steps of: analyzing the tolvaptan sodium phosphate freeze-dried powder injection by using a high performance liquid chromatography method so as to obtain a chromatogram, and determining the content of the impurities in the tolvaptan sodium phosphate freeze-dried powder injection based on the chromatogram, a chromatographic column adopted by the high performance liquid chromatography analysis method is a silica gel filled chromatographic column, a mobile phase A is a 0.01-0.03 mol / L monopotassium phosphate solution, the pH value of the mobile phase A is 6.0-8.0, and a mobile phase B is acetonitrile. The detection method is a method for detecting the impurity content in the tolvaptan sodium phosphate freeze-dried powder injection, can be used for supporting research and development work of pharmaceutical preparations, and is high in specificity, good in repeatability, reliable and capable of saving the detection cost.

The invention provides a codominant SSR (simple sequence repeat) marker closely linked with a tobacco xanthophyll gene qXant and an application method of the codominant SSR marker. The serial numbers of the codominant SSR marker closely linked with the tobacco xanthophyll gene qXant are TMy82029 and IDYK01541, and the nucleotide sequences of PCR (Polymerase Chain Reaction) amplification products of the codominant SSR marker closely linked with the tobacco xanthophyll gene qXant are respectively shown as SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 and SEQ ID No. 4. The application is the application of the codominant SSR marker closely linked with the tobacco xanthophyll gene qXant in detecting whether the tobacco xanthophyll gene qXant exists in a tobacco genome DNA (Deoxyribose Nucleic Acid) or not. Compared with a method in the prior art, the codominant SSR marker has the characteristics of accuracy, high efficiency, stability, convenience, low cost and no detection opportunity limitation, so that the molecular marker can be applied to molecular marker-assisted selection of the lutein gene qXant in tobacco breeding.

The present invention belongs to the technical field of nuclear fuel element manufacturing, and specifically relates to a fuel element grid strip stiffness detection clamping tool and a method of use. The present invention produces a detection fixture and a pressure head for two grid strips, and the clamping of the strip by the fixture fully meets the technical requirements. The double movable pressure head design of the present invention ensures full contact between the pressure head and the rigid convex, and fully realizes the simultaneous detection of the double rigid convex. The detection method of the present invention is accurate and reliable, and realizes the measurement of the strip clamping unit spring / rigid convex load-deformation curve.

The application discloses a fault detection method, device and equipment of a variable pitch system, and a readable storage medium. The variable pitch system can obtain a blade angle and a reference angle when a proximity switch is triggered, compare the blade angle with the reference angle, update forward counting data and / or negative counting data corresponding to the proximity switch according to a comparison result, and determine a fault type of the variable pitch system according to the updated forward counting data and negative counting data. According to the application, the blade angle and the reference angle when the proximity switch is triggered are used for fault detection, compared with fault detection according to a switch signal of the proximity switch, the problem that fault detection is not timely due to signal delay is avoided, and the application only needs to use two counting data to complete fault detection of the variable pitch system, so that the detection method is simple and reliable, and complex model operation is not needed.

The present invention provides a quality control method for a Ruren medicinal material and a Ruren formula granule, the quality control method comprising the following steps: extracting the Ruren medicinal material or the Ruren formula granule to prepare a test solution; mixing protocatechuic acid and an ethanol aqueous solution to prepare a reference solution; respectively detecting the test solution and the reference solution by high performance liquid chromatography to obtain the content of protocatechuic acid in the Ruren medicinal material or the Ruren formula granule and the characteristic spectrum of the Ruren medicinal material or the Ruren formula granule. The present invention constructs an HPLC characteristic spectrum of the Ruren medicinal material and the Ruren formula granule, fully demonstrating the chemical composition characteristics of the Ruren medicinal material and the Ruren formula granule; at the same time, the present invention establishes an HPLC content determination method for protocatechuic acid in the Ruren medicinal material and the Ruren formula granule, which is simple to operate, high in accuracy and good in stability.

The invention provides a honey refining mass transfer method suitable for pilot scale. The method covers the whole-process mass transfer rule of normal pressure and reduced pressure processes. The method comprises the following steps: taking a pilot scale normal pressure and reduced pressure process honey refining process as an inspection object, optimizing a measurement method of physical and chemical quality attributes, and collecting physical attributes including dynamic viscosity, complex viscosity, viscous modulus and elastic modulus and chemical attributes including moisture, 5-HMF and tetrasaccharide content. The invention further provides a mass transfer kinetic equation suitable for the two processes, and a correlation model among the refined honey viscosity (eta), the moisture (S) and the temperature (T) is established, so that the mass transfer rule of the pilot scale under the normal pressure and the reduced pressure process is systematically clarified. The method disclosed by the invention provides an innovative method and theoretical reference for mass transfer research of a complex process in a traditional Chinese medicine preparation process, and has important industrial application value.

The invention discloses a method for detecting related substances of (3R, 4S)-3-(2-bromoacetyl)-4-ethyl pyrrolidine-1-carboxylic acid benzyl ester, which is characterized by comprising the following steps of: detecting by adopting a high performance liquid chromatography under the chromatographic conditions that an octadecylsilane bonded silica gel chromatographic column is used as a stationary phase, a mobile phase A is a phosphoric acid aqueous solution, a mobile phase B is acetonitrile, a mobile phase C is acetonitrile and a mobile phase D is acetonitrile; carrying out gradient elution; the gradient elution procedure is as follows: within 0-5 minutes, the volume fraction of the mobile phase A is 60%-70%; within 5-35 minutes, the volume fraction of the mobile phase A gradually changes to 15%-25%; within 35-50 minutes, the volume fraction of the mobile phase A is 15%-25%; within 50-60 minutes, the volume fraction of the mobile phase A is 60%-70%. The method is good in specificity, high in sensitivity and low in detection cost, and a simple and reliable detection method is provided for quality control of the (3R, 4S)-3-(2-bromoacetyl)-4-ethylpyrrolidine-1-carboxylic acid benzyl ester.

The invention discloses a transformer anti-short-circuit capability evaluation system of a power system, relates to a transformer anti-short-circuit capability evaluation device, and aims to solve the problem of low reliability of an existing method for evaluating the anti-short-circuit capability of a transformer. According to the invention, the short-circuit current calculation module calculates the short-circuit current when various external short circuits occur; the first evaluation result output module obtains a transformer anti-short-circuit capability evaluation result A based on the short-circuit current; the short-circuit electrodynamic force output module establishes a finite element analysis model according to the short-circuit current calculated by the short-circuit current calculation module, and obtains corresponding short-circuit electrodynamic force; the second evaluation result output module is used for carrying out anti-short-circuit capability analysis on the power transformer according to the short-circuit electrodynamic force obtained by the short-circuit electrodynamic force output module to obtain an evaluation result B; and the comprehensive evaluation result output module is used for obtaining a final evaluation result by utilizing a comprehensive evaluation analysis method according to the evaluation result A and the evaluation result B. The method has the advantage that the reliability of short-circuit capability evaluation is improved.

The utility model discloses an intelligent brewing kettle which comprises a base, a kettle body assembly and a kettle cover body, the kettle body assembly is arranged on the base, a handle assembly is arranged on the kettle body assembly, and a display control assembly is arranged on the upper portion of the handle assembly. A detection assembly, a main control circuit board and a temperature control coupler are arranged in the base, the detection assembly corresponds to the kettle body assembly, a tea basket lifting mechanism is further integrally arranged in the kettle body assembly, and the display control assembly, the detection assembly and the tea basket lifting mechanism are connected with the main control circuit board. According to the brewing kettle, the structure of the brewing kettle is optimized, the reliability of electrical components is improved, and automatic brewing of drinks is achieved; the upper end of the screw rod is freely arranged, screw rod clamping failure caused by three-point fixing of the screw rod is avoided, in addition, the sensing plate arranged in the length direction of the screw rod is matched with the sensing contact piece synchronously moving on the nut, the position of tea leakage in the lifting pipe can be recognized and confirmed through sensing signals, the structure is simple, and the detection mode is stable and reliable.

The invention discloses a method for detecting the concentration of rosaxostat in human plasma based on an LC-MS / MS technology. The method is easy and convenient to operate, simple in pretreatment and short in mass spectrum collection time (3 min), all verification indexes meet the requirements of laws and regulations, rosaxostat can be accurately quantified, laboratory operation is simplified and facilitated to the maximum extent, and clinical requirements are met.

The utility model relates to a diameter measuring instrument for wire production. It includes: on -line detection seat, fixed detection wheel, swing arm, movable detection wheel and hall sensor, the first shaft body and second shaft body are horizontally rotated and are equipped on the on -line detection seat, the fixed detection wheel coaxial fixed mounting is in the first shaft body, the middle part fixed mounting of swing arm is in the second shaft body, the third shaft body is horizontally rotated and is equipped on swing arm, the movable detection wheel is coaxial fixed in the third shaft body and is opposite with the fixed detection wheel, the other end of swing arm is provided with lever arm and is prolonged, the end of lever arm is equipped with permanent magnet, the region of on -line detection seat near permanent magnet is installed with hall sensor, still be equipped with the elastic member of driving swing arm to the one side deflection of fixed detection wheel on the on -line detection seat. The utility model can carry out diameter measurement to the wire on the production line in real time, and the detection is more comprehensive and efficient.

The invention discloses a concrete sand fineness modulus and grading detection method, which comprises: 1, obtaining a sand sample, and flatly laying the sand sample on a glass slide; 2, determining the amplification factor of a microscope according to the particle size condition of the sand sample; step 3, under the determined magnification of the microscope, carrying out calibration and calibration on microscopic image measurement and analysis software; step 4, collecting an image of the amplified sand grain sample, then identifying particles in the image in microscopic image measurement analysis software, plotting a particle maximum diameter straight line, and measuring the particle diameter to obtain diameter data of the sand grain sample; and 5, calculating the fineness modulus and grading of the sand grain sample according to the diameter data. The detection method disclosed by the invention has the advantages of simplicity in operation, rapidness in detection, high detection accuracy and the like, and is suitable for a concrete mixing company to control the quality of the concrete sand and adjust the concrete proportion in real time according to a fineness detection result.

The utility model discloses a winder lock catch shell welding detection mechanism which is characterized in that the winder lock catch shell welding detection mechanism comprises a placement platform, a front insertion plate is fixedly arranged on the placement platform, the front insertion plate can be inserted into a belt buckle insertion end of a lock catch shell, a placement seat is further arranged on the placement platform, a connecting piece extending outwards of the lock catch shell can be placed on the placement seat, and the front insertion plate can be inserted into the belt buckle insertion end of the lock catch shell. A clamping assembly is arranged corresponding to the containing base, the clamping assembly is matched with the containing base to achieve vertical positioning of the connecting piece, a telescopic rod of the spring exerciser is connected with a hook claw base, a hook claw is arranged on the hook claw base in a swinging mode, and the hook claw is arranged on the hook claw base in a swinging mode. The claw can be clamped into the lock catch from the extending end of the connecting piece of the lock catch shell and tighten the upper shell body of the lock catch shell. The lock catch shell welding strength detection device is simple in structure, reasonable in design, capable of detecting the welding strength of a lock catch shell, convenient to operate and high in use flexibility.

The present invention provides a method for detecting the impurity content in a tolvaptan sodium phosphate lyophilized powder injection, wherein the tolvaptan sodium phosphate lyophilized powder injection is analyzed by a high performance liquid chromatography analysis method to obtain a chromatogram, and based on the chromatogram, the content of impurities in the tolvaptan sodium phosphate lyophilized powder injection is determined, wherein the chromatographic column used in the high performance liquid chromatography analysis method is a silica gel filled chromatographic column, the mobile phase A is a 0.01-0.03 mol / L potassium dihydrogen phosphate solution, the pH value of the mobile phase A is 6.0-8.0, and the mobile phase B is acetonitrile. The detection method of the present invention is a method for detecting the impurity content in the tolvaptan sodium phosphate lyophilized powder injection, which can be used to support the research and development of pharmaceutical preparations, has strong method specificity, good repeatability, is reliable, and can save detection costs.

The invention relates to the technical field of air conditioner equipment, in particular to an air conditioner outdoor unit and an air conditioner, and aims to solve the problems that the heat exchange efficiency and stability are affected due to the fact that control over the air suction superheat degree is not accurate enough in the running process of an existing air conditioner. In order to achieve the purpose, the air conditioner comprises a shell, the shell comprises dimming glass, the dimming glass is electrically connected with a power source and a controller, and the light transmittance of the dimming glass can change along with the change of voltage; and the condenser is installed at the position, close to the dimming glass, in the shell so that sunlight can penetrate through the dimming glass to irradiate the condenser, and through the arrangement, illumination can be reasonably utilized to conduct auxiliary adjustment on the superheat degree of the refrigerant so that the superheat degree can be controlled within a reasonable range.

The invention discloses a detection method of carbetocin injection related substances, and relates to the technical field of drug detection and analysis, the detection method comprises the following steps: preparing a solution; and detecting the carbetocin injection related substances by adopting a high performance liquid chromatography, and the like. According to the detection method provided by the invention, by selecting a proper mobile phase and controlling conditions of a gradient elution procedure, the use of an ion pair reagent in the mobile phase is avoided, and on the premise of ensuring effective separation of a main peak and impurities, the problems of poor baseline, low response, short service life of chromatographic column consumables and the like of an existing high performance liquid chromatography system are solved; the method has the characteristics of strong specificity, good precision, high accuracy, simplicity, high efficiency, low cost and the like, can be applied to quality control of the carbetocin injection, greatly reduces the use cost of chromatographic column consumables, and is more suitable for commercial production.

The invention provides an application of an SNP (Single Nucleotide Polymorphism) molecular marker related to a pig total nipple number character. The SNP molecular marker sites related to the total nipple number character of the high-generation cross-bred resource population of the large white pigs and the fortune fortune pigs are screened out through genome-wide association analysis (GWAS). The sites of the SNP molecular marker are respectively located on a TTC17 gene segment (2: 18782565) of a pig chromosome 2, the specific nucleotide sequence is as shown in SEQ ID NO.1, W at the 501bp is A or T, and the mutation leads to the A / T polymorphism of the molecular marker. The invention provides a new SNP molecular marker resource for the genetic improvement of the pig total nipple number character, can be applied to marker-assisted selection of pig genetic breeding, and is used for breeding sow varieties with more nipples.

The invention provides a codominant SSR (Simple Sequence Repeat) marker closely linked with a tobacco beta carotene gene qbCar and an application method. The serial numbers of the codominant SSR marker closely linked with the tobacco beta carotene gene qbCar are TMy80084 and TMy81298, and the nucleotide sequences of PCR (Polymerase Chain Reaction) amplification products of the codominant SSR marker closely linked with the tobacco beta carotene gene qbCar are respectively shown as SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 and SEQ ID No. 4. The application is the application of the codominant SSR marker closely linked with the tobacco beta carotene gene qbCar in detecting whether the tobacco beta carotene gene qbCar exists in tobacco genome DNA (Deoxyribonucleic Acid) or not. Compared with a method in the prior art, the codominant SSR marker has the characteristics of accuracy, high efficiency, stability, convenience, low cost and no detection opportunity limitation, so that the molecular marker can be applied to auxiliary selection of the beta carotene gene qbCar molecular marker in tobacco breeding.

The utility model relates to a refrigerator which comprises a refrigerator body, a refrigerating chamber is arranged in the refrigerator body, and an opening communicated with the refrigerating chamber is formed in one side of the refrigerator body. The door body is hinged to the box body; the shelf is arranged on the inner side of the refrigerating chamber and / or the door body; the detection device comprises a fixed seat, a movable seat, an elastic reset piece, a first contact switch and a controller, the fixed seat is placed on the shelf, the movable seat is arranged on the fixed seat and used for placing the water storage piece, the elastic reset piece is arranged between the fixed seat and the movable seat, and the first contact switch is arranged on the fixed seat and located below the movable seat; the first contact switch is electrically connected with the controller; when the water level of the water storage piece is larger than the preset water level, the movable base can be pressed to abut against the first contact switch downwards, and when the water level of the water storage piece is smaller than the preset water level, the elastic reset piece pushes the movable base to be separated from the first contact switch upwards. The equipment cost can be reduced, and the mode of detecting the water level of the water storage part is more reliable.

The invention discloses a device for verifying effectiveness of a storage battery airtightness detection machine and a detection method, and relates to the technical field of micro differential pressure leakage metering and storage battery production inspection, the device comprises a storage battery simulation shell and a leakage simulation part, and the storage battery simulation shell is provided with an air inlet and an air outlet; the air inlet is used for connecting an airtightness detector; the leakage simulation part comprises a pressure gauge and a pressure regulator which are sequentially connected with the exhaust port, the pressure gauge can detect the internal pressure value and the pressure change condition of the storage battery simulation shell, and the pressure regulator can control the internal pressure leakage amount of the storage battery simulation shell and simulate the leakage condition of the storage battery simulation shell. The air tightness detection device is simple and reasonable in structural design, the effectiveness of the air tightness detection machine is judged by detecting the air tightness of the simulated storage battery and utilizing the requirement degree met by the leakage rate, and therefore the reliability and effectiveness of air tightness detection of the storage battery in the production process are guaranteed.

The invention provides a codominant SSR (simple sequence repeat) marker closely linked with a tobacco rutin gene qRut and an application method of the codominant SSR marker. The serial numbers of the codominant SSR marker closely linked with the tobacco rutin gene qRut are IDYK02161 and TM20483, and the nucleotide sequences of PCR (Polymerase Chain Reaction) amplification products of the codominant SSR marker closely linked with the tobacco rutin gene qRut are respectively shown as SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 and SEQ ID No. 4. The application is the application of the codominant SSR marker closely linked with the tobacco rutin gene qRut in detecting whether the tobacco rutin gene qRut exists in a tobacco genome DNA (Deoxyribose Nucleic Acid) or not. Compared with a method in the prior art, the codominant SSR marker has the characteristics of accuracy, high efficiency, stability, convenience, low cost and no detection opportunity limitation, so that the molecular marker can be applied to auxiliary selection of the rutin gene qRut molecular marker in tobacco breeding.

The invention discloses an in-vitro dissolution method of a hydrobromic acid vortioxetine tablet, the in-vitro dissolution method adopts a paddle method, a dissolution medium is degassed purified water, and the dissolution medium contains 0.01% of cetyltrimethylammonium bromide (CTAB). The method comprises the following steps: taking samples at fixed time points at intervals, detecting the concentrations of the votioxetine hydrobromide samples at each time point by using a high performance liquid chromatograph to obtain a votioxetine dissolution curve which is good in homogeneity, smooth and free of jump points (that is, the dissolution amount at the latter time point is lower than that at the former time point), and predicting the in-vitro similarity of a tested preparation and a reference preparation. The cetyltrimethyl ammonium bromide (CTAB) is selected as a surfactant, compared with conventionally used lauryl sodium sulfate (SDS) and Tween 80, the cetyltrimethyl ammonium bromide has a better dissolution effect at a lower concentration, the dosage is smaller, the data uniformity is good, the relative standard deviation (RSD) is within 2%, and the accuracy and reliability of dissolution detection are remarkably improved. The dissolution method adopted by the invention can simulate the in-vivo release and absorption process, and the f < 2 > factor is combined to analyze the preparation difference, so that the quality and process difference between the reference preparation and the tested preparation can be effectively distinguished, and the evaluation on the dissolution behavior and quality consistency between the hydrobromic acid vortioxetine tablets is realized.