The invention discloses welding materials for butt welding of transition layers of a titanium clad steel plate and a welding method of the welding materials, and belongs to the technical field of metal material welding. The welding materials comprise a welding material for a surfacing layer and a near-titanium layer, a welding material for a bottoming layer, a welding material for a steel layer and a welding material for a titanium layer, wherein the welding material for the surfacing layer and the near-titanium layer comprises, by weight percentage, less than or equal to 0. 011% of carbon, less than or equal to 0.32% of silicon, 2.0-4.0% of manganese, less than or equal to 0.01% of phosphorus, less than or equal to 0.01% of sulfur, 10-17% of chromium, 2-16% of molybdenum, less than or equal to 2.0% of copper, less than or equal to 5.0% of ferrum and the balance nickel; and the welding material for the bottoming layer comprises more than or equal to 99.9% of nickel. The welding methodcomprises the following step that a groove form of a welding joint is designed to be an X-shaped groove, surfacing is carried out on the groove of the surfacing layer, then the near-titanium layer isfilled and welded with the near-welding material for the near-titanium layer, welding is carried out on the steel layer by using the welding material of ordinary carbon steel, and finally welding is carried out on the titanium layer by using an industrial TA2 welding wire. The welding materials and the welding method have the advantage that the fusion welding butt joint of the titanium clad steelplate has relatively high strength and toughness; and the problem of application bottleneck of welding of the titanium clad steel plate can be solved.