The invention relates to an intermediate heat conduction aluminum substrate manufacturing method. The method includes the steps that a silane coupling agent is selected and used for performing surface treatment on filler A and filler B; a glue solution is prepared from resin, heat conduction filler, the filler A and the filler B, wherein in percentage by mass, the resin accounts for 60%, the heat conduction filler accounts for 40%, and the proportion between the filler A and the filler B is 1:5-1:20; 1080 glass cloth is used as a base body, the 1080 glass cloth is coated with the prepared glue solution, and drying is performed on the 1080 glass cloth to obtain a glue sheet; copper foil, the glue sheet and an aluminum plate are overlapped in sequence and formed through pressing of a press, and an intermediate heat conduction aluminum substrate is obtained. According to the intermediate heat conduction aluminum substrate manufacturing method, detection is performed according to the IPC-TM-650-2.4.13.1 standard, a plate material is immersed into tin at the temperature of 288 DEG C for 10-15 minutes, layering and bubbling are avoided, the problem of low heat-conducting property of the aluminum substrate is solved, market requirements are met, economic benefits are obvious, and the implementation effect is good.