The invention relates to an open hole well packer, a rubber tube is sheathed outside an upper inner tube, an upper joint, the upper inner tube, a combined valve body, a lower inner tube and a lower joint are sequentially connected, the lower part of an upper rubber tube sheath covers the upper part of the rubber tube, the upper part of the upper rubber tube sheath is sheathed outside the upper joint, the upper part of a lower rubber tube sheath covers the lower part of the rubber tube, the upper part of a sealing sleeve is connected with the lower part of the lower rubber tube sheath, the lower part of the sealing sleeve is sheathed outside the combined valve body, an upper piston and a lower piston are mounted between the sealing sleeve and the lower inner tube, preset solution is perfused above the upper piston, the lower piston is arranged below the upper piston, a communicating hole is arranged on the upper piston, the communicating hole is positioned between the upper piston and the lower piston, a vertical pore canal is arranged on the combined valve body, a one-way valve is mounted at the upper part of the vertical pore canal, the one-way valve is designed for enabling the rubber tube to be in expansion state permanently, the rubber tube is expanded by the preset solution, and the one-way valve can not be corroded and damaged, so that the rubber tube can work effectively for a long time and meet the requirement on permanent blocking of the well bottom of an open hole well in an oilfield.