The invention discloses a
biosynthesis method of perylenequinonoid compounds, in particular a
biosynthesis method of perylenequinonoid compounds and specifically relates to optimization of a
fermentation process in a
biosynthesis process. A
fungus, which grows in Yunnan western mountainous area and is identified to belong to ascomycetes, hypocreaceae and hypornyces, serves as a strain and a
solid mixture, which contains maize
powder, wheat
bran and bean drges, is taken as a
solid-state culture medium. The
solid-state culture medium is sterilized and the strain is inoculated, and
fermentation is conducted at 21-23 DEG C for no less than 9 days, so that a
brick-red solid fermented product containing the perylenequinonoid compounds is obtained, therefore a bacterium block containing the perylenequinonoid is obtained through biosynthesis, wherein the bacterium block contains biosynthesis products of the invention, namely such perylenequinonoid compounds as elsinochrome A, hypocrellin A, hypocrellin B, hypomycin A and B, and the like. A finished perylenequinonoid compound product can be obtained by
drying and crushing the bacterium block and by extracting and separating. According to the biosynthesis method disclosed by the invention, the total amount of the perylenequinonoid compounds in the finished product is improved.