An environment-friendly nano-epoxy silicone heavy anti-corrosion coating comprises a component A and a component B, wherein the component B is polyamide, and the component A is prepared by water-borne epoxy resin, a solvent, silicon carbide, aluminum oxide, nano-quartz powder, titanium dioxide power, zinc powder, aluminum powder, ceramic powder, cobalt-nickel ultrafine metal powder and graphite. A using method of the environment-friendly nano-epoxy silicone heavy anti-corrosion coating is that the component A and the component B are mixed evenly according to the weight ratio of 30-50:1 and then directly sprayed or brushed on the surface of an anti-corrosion object at the normal temperature. A coating layer formed by the coating has good abrasion resistance, corrosion resistance, impact resisting performance and flexibility and can effectively isolate corrosion of acid, alkali, salt and sea water. The surface of the coating layer is compact and smooth and has small resistance to a transmission medium. The coating can be widely applied to oil transportation pipelines, oil storage tanks, chemical equipment, ships, grinding wheel blades, pumps, dust removers, offshore steel structures and the like. In addition, the environment-friendly nano-epoxy silicone heavy anti-corrosion coating is water-based coating, does not contain harmful ingredients and is convenient and efficient in use.