The invention discloses a Agaricus blazei chewable tablet capable of alleviating oral inflammation, which comprises the following components in parts by weight: fresh Avalokitesvara basil leaves, Radix Ophiopogon japonicus, Sanyinhua, licorice, bamboo leaves, glutinous rice flour, potato flour, kelp powder, defatted Animal bone meal, Ganoderma lucidum fruiting body extract, Agaricus blazei fruiting body extract, yeast, niacin, folic acid, vitamin B, vitamin C, konjac powder, edible plant ash soaking liquid, sodium hydroxymethylcellulose, dextrin, appropriate amount of water. The Agaricus blazei chewable tablet of the present invention is made by compressing and baking fermented Guanyin chai liquid together with glutinous rice flour, potato flour, kelp powder, defatted animal bone powder, ganoderma lucidum fruiting body extract, and Agaricus blazei fruiting body extract. It is delicious and has obvious anti-inflammatory effect on oral inflammation. Long-term consumption can cure oral ulcers, oral odor, periodontitis, gingivitis and other oral inflammations, and it is not easy to relapse. At the same time, it can improve the body's non-specific immunity and specific immunity.