The invention provides a low inclusion pipeline steel production method. The low inclusion pipeline steel production method is characterized in that pipeline steel comprises 0.062-0.065% of c, 0.25-0.3% of Si, 1.75-1.78% of Mn, less than or equal to 0.015% of P, less than or equal to 0.005% of S, 0.07-0.095% of Nb, 0.010-0.012% of Ti, less than or equal to 50% of Al, 0.5-0.65% of Cr, 0.55-0.6% ofMo, 0.2-0.25% of Ni, 0.15-0.19% of Cu, 0.005-0.008% of W, 0.0001-0.0004% of Zr, 0.0001-0.005% of Ta, 0.0001-0.0005% of rare earth (Sc+Y), 0.0001-0.0005% of B, 0.001-0.005% of N, and the balance beingFe and inevitable impurity elements, wherein the mass ratio of Sc to Y is 4-5: 1; the final structure comprises 90-92% of needle-shaped ferrite, 3-5% of polygonal ferrite and 3-5% of martensite according to the area percentage; the average grain size is 2-5 microns; the yield strength is 930-960 MPa; the tensile strength is 1050-1250MPa; the impact toughness is 150-170J at the temperature of minus 40 DEG C; and the extension rate is 17-19%. The process route comprises the steps of preparing materials according to a ratio, treating molten iron in advance for desulfuration, smelting in a converter, refining in a LF (ladle furnace), carrying out RH refining, carrying out continuous casting, rolling and reeling.