76results about How to "Great development and application value" patented technology

The invention discloses a styryl-containing 1,3,4-oxadiazole thioether compound. The structural general formula (I) is as follows: R1 is hydrogen, 4-methoxyl, 4-chlorine, 4-fluorine or 4-bromine; R is methyl, ethyl, benzyl, 2,5-dichlorobenzyl, 4-fluorobenzyl, 4-hlorobenzyl, 2-methylbenzyl, 4-nitrobenzyl, 1,1,2-trifluoro-butenyl or the like. The styryl-containing 1,3,4-oxadiazole thioether compound has activities of killing citrus nematode and meloidogyne incognita chitwood. (The formula (I) is as shown in the description.).

The invention discloses a fresh keeping method for plum fruit, comprising the following steps: (1) immersing plum fruit in chitosan solution with a concentration ranging from 0.1g/100ml to 3.0 g/100ml at room temperature; (2) refrigerating the plum fruit immersed in step (1); (3) when entering into shelf life, keeping refrigerated plum fruit in an enclosed device, which contains 1-methyl cyclopropene gas with a concentration ranging from 0.5 mul/L to 5.0 mul/L, for 12-24 hours at room temperature; wherein, the concentration of 1-methyl cyclopropene gas is preferably in the range of from 1.0 mul/L to 2.0 mul/L. The fresh keeping method for plum fruit of the present invention has the advantages of high food health safety, simple application, easy spread, little investment but quick result, low price, broad market, notable economic and social profit etc, which is suitable for China and has great development and application value.

The invention provides a composition for rapidly alleviating fatigue and enhancing resistance, wherein the composition comprises electrolyte, trace elements and nutrients, the preparing process comprises the steps of batching by determined proportion, charging trace elements such as copper, Zinc, and meeting the formula designed requirement.

The invention discloses a method for preparing total flavones of Tridax procumbens and application thereof, which belong to the technical field of extraction and preparation methods of flavones. The method comprises the steps of: taking crude powder of the Tridax procumbens as a raw material, using aqueous ethanol as a solvent for ultrasonic extraction, recovering the ethanol by performing vacuum concentration on a filtrate, performing ultrasonic decolorization by activated carbon after obtaining a concentrated solution, continuing to perform vacuum concentration after removing the activated carbon, separating and enriching the concentrated solution through a macroporous absorbent resin, using the aqueous ethanol for gradient elution, and mixing an aqueous ethanol eluent with certain proportion for vacuum concentration drying to obtain dry powder of an extract of the total flavones of the Tridax procumbens. The preparation method has the advantages of simple process, convenient operation, small equipment investment, small using amount of the solvent, no environmental pollution, low production cost, and high yield of the extract.

The invention relates to an Aspergillus versicolor strain, particularly an Aspergillus versicolor strain with antibacterial activity. The invention provides an Aspergillus versicolor strain, which has favorable inhibiting actions on Bacillus subtilis, Bacillus pumilus, Staphylococcus aureus and other bacteria and provides references for developing new antibacterial drugs and food preservatives. The Aspergillus versicolor with antibacterial activity is Aspergillus versicolor CWJ2, and is collected at China Center for Type Culture Collection; and the collection date is April 16th, 2014, and the collection number is CCTCC NO:M2014130. The Aspergillus versicolor CWJ2 has strong inhibiting actions on Bacillus subtilis, Bacillus pumilus, Staphylococcus aureus and other bacteria.

The invention belongs to the technical field of organic synthesis, and concretely discloses a bridging type arylpyrazole amide compound as well as a solvent heat one-pot synthesis method and application thereof. The solvent heat one-pot synthesis method is used for preparing a target object; the reaction time is short; a solvent cannot be volatilized in a sealed system and can be recycled; the production cost is effectively reduced; the advantages of energy saving and environment protection are realized; in addition, the operation is simple; the yield is higher. The prepared bridging type arylpyrazole amide compound (II) has good biological activity, has high activity particularly in the aspects of agriculture, gardening, flowers and sanitation insect prevention and controlling, and belongs to an efficient, low-toxicity, broad-spectrum, environment-friendly and green insecticide, so that great development and application values are realized.

The invention provides a preparation method of the total flavone from the natural plant, belonging to the technical field of the plant. The method comprises the steps of: taking the aeschynanthus moningeriae as a raw material, and taking alcohol containing water as dissolvent to extract the tissue in a breaking way; filtering in a pumping way, merging filter liquor, and recovering the dissolvent by means of flashing and concentrating; and separating and enriching the obtained concentrated liquor by macroporous absorption resin, performing gradient elution on the alcohol containing water, merging the eluent of the alcohol containing water with a certain proportion to recover the dissolvent by means of flashing and concentrating, and continuously performing the vacuum drying on the solvent to obtain dried powder so as to obtain the total flavone extractive of the aeschynanthus moningeriae. The preparation method is simple in technology, advanced in extraction and concentration technology, convenient in operation, low in cost, green and high-efficiency, so that the total flavone content in the extractive is 32.27%-43.69%, the extracting rate is 8.56%-13.56%, and the transferring rate is as high as 72.33%-84.45%. The preliminary extracorporeal bioactivity test shows that the specific total flavone extractive of the aeschynanthus moningeriae has a certain antibacterium activity and antioxidation activity.

The invention belongs to the technical field of organic synthesis, and particularly discloses 3-cyano-5-acrylamido-1-(2,6-dichloro-4-trifluoromethylphenyl)-pyrazole compounds, and a solvothermal one-pot synthesis method thereof and application thereof. The solvothermal one-pot synthesis method for preparing the target substances has the advantage of short reaction time; and the solvent can not be easily volatilized in the closed system, and can be recycled, thereby effectively lowering the production cost. The method has the advantages of energy saving, environment friendliness and higher, and is simple to operate. The 3-cyano-5-acrylamido-1-(2,6-dichloro-4-trifluoromethylphenyl)-pyrazole derivatives (II) have favorable bioactivity, especially have high activity in the aspects of agriculture, horticulture, flowers and sanitary insect pest control, can be self-degraded under the irradiation of sunlight, are green low-residue compounds with insecticidal activity, and thus, have great development and application values.

The invention relates to a preparation method of copper alloy for high-power LED (light emitting diode) phase-transition internal/external heat dissipators, which comprises the following steps: (1) determining the maximum allowable temperature of high-power LED; (2) determining the phase transition temperature range of the copper-base alloy; (3) determining the percents of the alloy elements; (4) carrying out sample size melting; (5) carrying out heat treatment on the molten sample; (6) testing to verify whether the transition transition point conforms to the designed value; (7) adjusting the composition; (8) producing and melting; (9) casting; and (10) carrying out homogenizing treatment. The high-power LED heat dissipator made of the copper-base alloy material not only has the copper clad layer in the original built-in copper heat-dissipation pad and printed circuit board (PCB) as well as the conductive heat dissipation and radiation heat dissipation in the external aluminum heat dissipator, but also has the function of phase-transition heat absorption below junction temperature. Every gram of alloy can absorb 7-9 joule more of heat quantity. Besides, the manufacturing cost of the copper alloy is lower than that of pure copper. Therefore, the invention has a high development and application value in manufacturing high-power LED heat dissipators.

The invention relates to a welding positioning device suitable for airplane exhaust pipes, in particular to the technical field of positioning during airplane exhaust pipe welding. A positioning plate I, a clamping plate positioning device II, a clamping plate positioning device I and a positioning plate are sequentially installed on a base from left to right. A hook-shaped clamping device used for conducting clamping, cylinder bolts and cylindrical pins are arranged on the positioning plate I, wherein the cylinder bolts are used for product positioning and provided with handles. The inner shape of the clamping plate positioning device II and the inner shape of the clamping plate positioning device I conform to the appearance of a product. By means of the welding positioning device, the manufacturing period is shortened, the manufacturing cost is reduced, the welding positioning device is light and convenient to use, the manufacturing period of the product is shortened, and the beneficial effect that general tools are accurate in positioning is used. The welding efficiency is improved, the appearance sizes of the airplane exhaust pipes can be well ensured, and the airplane exhaust pipes are prevented from deforming during welding. Therefore, practicability is high, and the welding positioning device is easy to use and popularize and has great development and application value in professional fields.

The invention relates to the technical field of organic synthesis, in particular relates to 3-oxime ester-5-oxazinonepyrazole compounds and a method for synthesizing the compounds by utilizing an ultrasonic method, and provides an application of the compounds. The method disclosed by the invention adopts ultrasonic waves to synthesize the 3-oxime ester-5-oxazinonepyrazole compounds, the costs of synthetic raw materials are lower, the reaction conditions are mild, the operation is simple, and the yield is higher; and the prepared oxime ester derivatives (I) based on the oxazinonepyrazole skeleton have good bactericidal weeding and insecticidal biological activity, and particularly exhibit high activity in aspects of agriculture, gardening, flowers, sanitary weeding and prevention and control of pests, thereby having great development and application value.

The invention relates to a Vibrio anguillarum strain and an application method thereof and in particular relates to a Vibrio anguillarum MN strain. The Vibrio anguillarum MN strain is separated from a Scophthamus maximus body, is a wild strain with stronger toxicity and has a preservation number of CGMCC (China General Microbiological Culture Collection Center) No.7198. Vaccine antigens of one or more expression products of inactivated thallus, bacterial ghost components, attenuated strains, protective antigens, antigen subunits, antigenic determinants or antigenic gene expression vectors, which are prepared from the Vibrio anguillarum MN strain can be applied to an immunological technology of the Vibrio anguillarum MN strain; and the vaccine antigens in the immune application can be inoculated by adopting an injection immunization, trauma immunization, immersion bath immunization or oral immunization manner, and can be independently used, or used together with other adjuvants, or prepared into single preparations which can be used together with the adjuvants or not together with the adjuvants.

The invention is a compound traditional Chinese medicine and preparation for curing chronic hepatopathy, comprising the 12 Chinese traditional medicines (medicinal materials, prepared products and extractives): Phyllanthusurinaria L, verbena, kuh-seng, Spreading Hedyotis Herb, pseudo-ginseng, danshen, peach kernel, radix bupleuri, prepared rhizome of rehmannia, ginseng, fuling, and Liquoricee in a certain proportion in the range of 1%-99%, and each accounts for 2%-15% of total weight. It has efficacies of clearing heat and detoxifying, comforting liver and removing gloomy and promoting blood circulation and tonifying, and has a very good curative effect on liver fibrosis and chronic liver damage.

The invention discloses a method for producing all-vitamin mineral oral liquid by microorganism fermentation. The method includes the steps: selecting strains; adding mineral substances in a classified manner by multistage fermentation; determining tank switching and fermentation end points according to the growth density, the form and the pH (potential of hydrogen) index of the strains; adding vitamins into a fermentation tank after three-stage fermentation; sterilizing the oral liquid; filling the oral liquid and the like. By means of microorganism liquid fermentation, enrichment and transformation, various mineral substances and vitamins essential to human bodies are added into a culture medium in the classified manner according to a certain regularity, microorganisms absorb and transform inorganic mineral elements in the growing process and are in an organic form, and antagonism and competition of the mineral substances are avoided by means of multistage addition and fermentation. The healthcare function of the microorganisms is increased, and the method has higher development and application values and fine economic and social benefits.

The present invention belongs to the technical field of genetic engineering and enzyme engineering, and particularly relates to a method for continuous production of c-di-AMP by using immobilized DisA protein. The method comprises: 1, DisA gene transformation, wherein DisA gene and cbm gene are fused through gene engineering to construct a recombinant plasmid vector; 2, recombinant plasmid transformation and CBM-DAC fusion protein expression; 3, one-step DAC enzyme purification and immobilization; 4, continuous c-di-AMP production; and 5, reaction product separation concentration and purification. According to the present invention, the characteristic that the CBM domain is combined with cellulose and no hydrolysis exists is specifically utilized, the process is mature, the production cost is low, the environmental protection is provided, the types of the prepared DAC enzyme are diversified, the sources are wide, the concentration and the purity are high, the enzymatic reaction efficiency is high, and the good development and application value is provided.

The invention discloses a plane jig pipe fitting tool laser tracking instrument target installing and locating part. The target installing and locating part (1) is of a cylindrical structure, the cylindrical structure is provided with a step, the diameters of two sides of the cylindrical structure are not equal to each other, a cylindrical face with a diameter of d on the left of the step serves as an installing face where a digital pipe fitting model (2) is installed, the left lateral side of the step serves as an axial locating face, a through hole with the diameter as D is formed in the center of the target installing and locating part (1) and is used for locating and installing a laser tracking instrument target (4) seat, a pin hole is formed in a cylinder on the right of the step and is connected with a locator rod (3) through a cylindrical pin, the diameter d of the cylindrical locating face of the target installing and locating part (1) can be decided according to inner diameters of standard pipe fittings, and the target installing and locating part can be manufactured into serial products. The plane jig pipe fitting tool laser tracking instrument target installing and locating part is simple in structure, convenient to operate and high in locating accuracy; the problem of the plane jig pipe fitting tool laser tracking instrument target installing and locating part is solved; the assembling efficiency of tool manufacturing is improved; the manufacturing period of a tool is shortened; and the machining error is reduced.

The invention belongs to the technical field of natural medicine, and particularly relates to a flowering day lily extract, a preparation method and usage of the flowering day lily extract, and an antidepressant drug combination. The invention discloses the simple, economic and environment protective preparation method of the flowering day lily extract, and products of the preparation method, andfurther discloses application of the flowering day lily extract to preparation of antidepressant drug, and the antidepressant drug combination taking the flowering day lily extract as an active substance. The usage is verified through pharmacology experiment. According to the flowering day lily extract, the preparation method and usage of the flowering day lily extract, and the antidepressant drugcombination, application value of the flowering day lily is greatly developed, an intestinal microbial metabolites hypothesis is firstly adopted and applied to the flowering day lily extract, it is indicated that the flowering day lily extract can obviously influence intestinal microbe of a mice for treating depression, and good application prospects are achieved.

The invention relates to a preparing method of an antifungal natural active substance, and belongs to the technical field of natural plant preparations. The method is characterized by comprising following steps: 1) smashing and mixing; 2) extracting; 3) flashing and concentrating; 4) preparing a diethyl ether extract product; 5) preparing an ethyl acetate extract product; and 6) mixing dry powder of the diethyl ether extract product in the step 4) and dry powder of the ethyl acetate extract product in the step 5) to obtain the antifungal natural active substance. According to the preparing method, extract liquid is subjected to vacuum concentration separately to obtain the diethyl ether extract product and the ethyl acetate extract product. The two extract products have high functions of treating plant pathogenic fungus infection and human body superficial fungus infection. The antifungal natural active substance can be used as botanical fungiticides, and can be used for treating and preventing fungal infection and human skin fungal infection.

The invention relates to the technical field of bio-pharmaceuticals, in particular to application of rheum australe root in preparing medicine for treating cerebral hemorrhage or reducing the same caused by rtPA thrombolytic therapy after cerebral ischemia. Researches show that activation of MMP-9 and overexpression of inflammatory factors like IL-1 beta and TNF alpha induced by rtPA in an ischemia condition can be reduced by the rheum australe root; measuring of four indicators of thrombin shows that the rheum australe root can effectively protect vascular injury caused by rtPA and lower cerebral hemorrhage risk; can inhibit thrombosis and protect blood vessels, has certain anti-coagulation effect and can effectively improve adverse effects like cerebral hemorrhage and brain tissue injurycaused by giving rtPA after cerebral ischemia so as to improve animal survival condition. Experiment results indicate that the rheum australe root has great development and application value in lowering cerebral hemorrhage risk caused by clinically using rtPA thrombolytic therapy for stroke and increasing survival rate of patients.