The invention discloses a charge pump applied to a frequency synthesizer. The charge pump comprises a charge-discharge current branch and an output impedance multiplication circuit. The charging and discharging current branch is composed of a unit negative feedback loop and a current source, wherein the unit negative feedback loop is composed of a complementary CMOS switch and a rail-to-rail inputand output amplifier, and the charging and discharging current branch is used for charging and discharging an output node and eliminating a clock feed-through effect and a charge sharing effect. Theoutput impedance multiplication circuit is composed of a folding type cascode structure and is used for improving the output impedance of the charge pump. The output impedance multiplication circuit comprises a reference current source, first, second, third, fourth, fifth, seventh, eighth, tenth, eleventh and sixteenth NMOS tubes, and first, second, third, fourth, sixth, seventh, ninth, tenth andfifteenth PMOS tubes. The invention is suitable for the drain terminal switch charge pump with good matching characteristic under low voltage, improves the matching degree of charging and dischargingcurrent, improves the phase noise of the frequency synthesizer, and improves the output impedance of the charge pump.