The invention relates to the technical field of
organic synthesis, in particular to a preparation method of azacyclo-
sulfide and a purification method of same. The preparation method comprises the steps of
raw material extraction, substrate expansion, nucleophilic preparation, oxidation modification, vibration, standing and purification. A reaction tank comprises a tank body, a reaction vessel anda
burette; a plurality of
layers of reaction vessels are arranged in the tank body; the
burette pipeline comprises a
titration disc and a shunt
pipe; because the dispersion degrees of the substratesin the
mixed solution are different and the speed of adding the substrates into the reaction tank is changed, the purity effect of the required azacyclo-
sulfide extraction can be influenced; therefore, according to the invention, the reaction vessel and the
titration disc are correspondingly arranged in the reaction tank; the reaction vessel is provided with the inclined reaction tank, the speed of a substrate solution entering the
titration disc is balanced by matching with the shunt
pipe inclined to the titration disc, and the
servo motor drives the inclined reaction tank to rotate, so thatthe substrate added into the reaction vessel uniformly covers the surface of the reaction vessel, and the preparation purity of the azacyclo-
sulfide is improved.