The invention discloses a nano-calcium carbonate modification method and an application of nano-calcium carbonate to a PVC (polyvinyl chloride) wood-plastic plate. The nano-calcium carbonate modification method includes the steps: adding dispersing agents and crystal form control agents in a carbonation process; performing modification through diglycolamide oleate borate and dodecafluoro heptyl propyl polyhedral oligomeric silsesquioxane. The obtained modified nano-calcium carbonate has high dispersity, high toughness, weather resistance, flame resistance and excellent mechanical properties. The PVC wood-plastic plate comprises, by weight, 100 parts of PVC resin, 10-20 parts of EVA (ethylene-vinyl acetate) resin, 40-60 parts of bamboo powder, 30-50 parts of modified nano-calcium carbonate,3-5 parts of asbestos fibers, 4-6 parts of shell powder, 3-5 parts of polyacrylamide, 1-3 parts of polyether modified polydimethylsiloxane, 3-5 parts of composite foaming agents, 1-3 parts of coupling agents, 2-4 parts of stabilizing parts, 1-3 parts of lubricants, 0.5-1.5 parts of antibacterial agents and 3-5 parts of processing aids. The PVC wood-plastic plate has the advantages of high strength, high toughness, strong impact resistance, good flame resistance, strong antibacterial property, heat resistance, difficulty in deformation, good stability and the like.