The invention discloses a method for extracting fennel
essential oil based on a
choline chloride-
citric acid natural eutectic
solvent. According to the method, fennel fruits are crushed, a
choline chloride-
citric acid NADES
aqueous solution is used as a
solvent, fennel
essential oil is extracted by using an ultrasonic-assisted
steam distillation method, the yield of the fennel
essential oil and the contents of four main components such as trans-
anethole are used as evaluation indexes, weights are given to the indexes by using an
entropy weight method, and comprehensive scores are calculated. And finally, evaluating the anti-inflammatory activity of the fennel essential oil by using an RAW264.7
cell LPS induced anti-inflammatory model. The natural eutectic
solvent is combined with the ultrasonic-assisted
steam distillation technology, the extraction method has the characteristics of short extraction time, easiness in operation and low cost, and the fennel essential oil obtained by the novel extraction method is higher in yield, more in volatile components, better in anti-inflammatory activity and suitable for industrial production. A new means and a theoretical basis are provided for industrial popularization of the fennel essential oil and application of the fennel essential oil in the field of biological medicines.