689 results about "Vinylbital" patented technology

The invention relates to a synthesis method of 1, 2-bis (4-vinyl phenyl) ethane, which comprises the following steps: 1) under the action of magnesium or zinc, carrying out self-coupling reaction on benzyl halide at a benzyl position to obtain 1, 2-bis (4-halogen phenyl) ethane, and 2) preparing the 1, 2-bis (4-vinyl phenyl) ethane from the 1, 2-bis (4-halogen phenyl) ethane, which is selected from any one of the following schemes: 2i: carrying out self-coupling reaction on the 1, 2-bis (4-vinyl phenyl) ethane obtained in the step 1) to obtain the 1, 2-bis (4-vinyl phenyl) ethane. The preparation method comprises the following steps: preparing a Grignard reagent from 1, 2-bis (4-halogen phenyl) ethane, and coupling the Grignard reagent with vinyl chloride to prepare 1, 2-bis (4-vinyl phenyl) ethane; and (2iii) coupling the 1, 2-bis (4-halogen phenyl) ethane obtained in the step (1) with vinyl magnesium chloride to prepare the 1, 2-bis (4-vinyl phenyl) ethane. According to the invention, the 1, 2-bis (4-vinyl phenyl) ethane is prepared from p-benzyl halide through two-step reaction at a relatively high yield, and the yield of the two-step reaction can reach 86.9%.

The invention discloses a nano blocking agent for drilling fluid and a preparation method thereof, and belongs to the technical field of blocking agents, the nano blocking agent for drilling fluid is prepared by reaction of a core layer blocking agent and a shell layer blocking agent, the core layer blocking agent is prepared by reacting nano silicon dioxide, gamma-methacryloxypropyltrimethoxysilane and a first part of vinylphosphonic acid, and has secondary blocking capability; and the shell blocking agent is prepared by reacting a second part of vinyl phosphonic acid, styrene and 2-dodecene-1-yl succinic anhydride, and has the characteristic of flexibility. The nano plugging agent has rigid supporting and flexible deformation capabilities, and the high-temperature stability and compressive strength of a plugging layer are remarkably improved. The chemical binding force of the plugging agent and the rock is enhanced; the hydrolysable methoxyl reserved in the core layer provides a secondary plugging function, and the plugging validity period is prolonged. The invention relates to a preparation method of a nano blocking agent for drilling fluid, which is used for preparing the nano blocking agent for drilling fluid.

The invention provides a salt-responsive temperature-resistant salt-resistant water-based drilling fluid tackifying filtrate reducer as well as a preparation method and application thereof, and belongs to the technical field of drilling. The tackifying filtrate reducer is prepared from the following raw materials in parts by mass: 30 to 50 parts of 1-(2-carboxyethyl)-2-vinylpyridine, 20 to 40 parts of (3-(methacrylamido) propyl) dimethyl (3-thiopropyl) ammonium hydroxide inner salt, 35 to 55 parts of N, N-dimethylacrylamide, 10 to 25 parts of 4-vinylpyridine, 300 to 500 parts of water and 1 to 5 parts of an initiator. According to the filtrate reducer, cations and anions are concentrated on one monomer molecule, so that the synthesized product contains the cations and the anions with the same charge number, has good adsorption capacity and salt response characteristics, is compatible with salt essentially, can effectively resist high temperature and high salt, and can be recycled. And the viscosity-increasing and filtrate-reducing agent has good viscosity-increasing and filtrate-reducing effects on the drilling fluid.

The invention discloses a silica gel material and a preparation method thereof, a silica gel tube, an implant and a preparation method and application thereof. The silica gel material comprises the following components in parts by weight: 100 parts of R-vinyl polysiloxane; 10 to 80 parts of a reinforcing agent; 0.000002 to 1 part of a catalyst; wherein R in the R-vinyl polysiloxane is substituted or unsubstituted straight-chain alkane or branched alkane of C1-C5, and substituted or unsubstituted aromatic hydrocarbon of C6-C20, and R in the R-vinyl polysiloxane is substituted or unsubstituted straight-chain alkane or branched alkane of C1-C5, or substituted or unsubstituted aromatic hydrocarbon of C6-C20; the content of vinyl in the R-vinyl polysiloxane ranges from 0.1 mol% to 0.5 mol%; the components contained in the reinforcing agent comprise hydrophilic groups; the content of Si-H groups in the hydrogen-containing silicone oil is 0.18 mol% to 1.6 mol%; the molar ratio of the Si-H group in the hydrogen-containing silicone oil to the vinyl group in the R-vinyl polysiloxane is (0.5-10): 1; optionally, the composition also comprises an inhibitor. According to the silica gel material provided by the invention, the permeability of water to the silica gel tube is increased while the mechanical property is met, so that the release amount of a medicine is increased, and the defect of low in-vitro release degree in the prior art is improved.

The present disclosure relates with the development of a process for producing gels from polymeric materials crosslinked with organic agents and their use controlling water in porous media under high salinity and temperature conditions. The characteristics of these gels enable them to have a good performance withstanding extreme conditions in mature Mexican oil wells and in others located in other parts of the world. The gels featured in the present disclosure include novel ionic terpolymers based on acrylamide (AM), N-vinylpyrrolidone (VP), N,N′-methylenebisacrylamide (BAA), 1-vinyl-3-butylimidazolium bromide (VIM4C[Br]) and organic crosslinking agents.

The present invention provides a divinylbenzylfluorene and a preparation method and application thereof, a divinylbenzylfluorene hydrocarbon resin and a preparation method and application thereof, and relates to the technical field of high-frequency substrate materials. The divinylbenzylfluorene hydrocarbon resin prepared by using one or a mixture of any proportion of 9,9-bis(2-vinylbenzyl)-9H-fluorene and 9,9-bis(4-vinylbenzyl)-9H-fluorene provided by the present invention as raw materials has very low dielectric constant and dielectric loss tangent, and the higher the content of 9,9-bis(2-vinylbenzyl)-9H-fluorene, the smaller the dielectric loss tangent of the divinylbenzylfluorene hydrocarbon resin; moreover, the solubility of 9,9-bis(2-vinylbenzyl)-9H-fluorene and 9,9-bis(4-vinylbenzyl)-9H-fluorene provided by the present invention in toluene and 2-butanone is high, and has good application prospects as a cross-linking agent of the main resin or olefin resin component of a high-frequency substrate.

The invention provides a method for synthesizing 1, 2-bis (4-vinyl phenyl) ethane, which comprises the following steps: adding a first solvent, methyl triphenyl phosphine halide and strong alkali into a reaction flask, and uniformly stirring to obtain a first mixed solution; heating the first mixed solution and carrying out reflux reaction for 1 hour; dropwise adding a 1, 2-bis (p-formaldehyde phenyl) ethane solution until the reflux reaction is finished to obtain a second mixed solution; reducing the temperature of the second mixed solution to room temperature, and adjusting the pH value of the second mixed solution to obtain a first solution; layering the first solution, and taking an organic layer; adding a polymerization inhibitor into the organic layer to obtain a second solution; concentrating the second solution to obtain a 1, 2-bis (4-vinyl phenyl) ethane crude product; adding a poor solvent into the crude product, stirring and crystallizing; filtering the crystal to obtain a filter cake, adding a second solvent into the filter cake, and washing and drying the filter cake to obtain 1, 2-bis (4-vinyl phenyl) ethane; the method for synthesizing the BVPE is simple and low in raw material cost, and the synthesized BVPE is high in purity and free of product isomeride.

The invention relates to the technical field of oil and gas field development, in particular to a double-network CO2 response type gel particle and application thereof.The first-layer network is formed by covalent bonds between acrylamide, zwitterions and CO2 response monomers (composed of vinylpyridine and DMAEMA) in the gel particle and a cross-linking agent, and the first-layer network is formed by covalent bonds between Ca < 2 + > in mineralized water, pyridine, SO3 <-> in the zwitterionic monomers and coordinated water; coordination bonds exist among Mg < 2 + >, pyridine, carboxyl (acylamino is partially hydrolyzed) and coordinated water, a second-layer network is formed under the synergistic effect of pi-pi bonds among aromatic rings, and the strength of the gel is enhanced through the toughness of the double-network structure. Due to the introduction of an aromatic ring sulphobetaine monomer and water molecules carried by coordinate bonds, the strength of the gel particles in mineralization water is increased, and meanwhile, the gel particles show higher water-retaining property. Due to the introduction of CO2 response monomers with different pKa values, the particles have good CO2 responsiveness, and still have the dual-network structure in mineralized water after response.

The invention discloses vinyl silicone oil as well as a preparation method and application thereof, and belongs to the technical field of organic silicon industry. The structural formula of the vinyl silicone oil is shown as a formula (1) or a formula (2), # imgabs 0 # formula (1) and # imgabs 1 # formula (2), the structural formula of M is shown as a formula (3), and in the formula (1), the formula (2) and the formula (3), m is larger than or equal to 3 and smaller than or equal to 2000, n is larger than or equal to 1 and smaller than or equal to 600, and m and n are integers; r1, R2, R3, R4, R5 and R6 can be one or more of methyl, ethyl, vinyl, phenyl and trifluoropropyl. The vinyl silicone oil is uniform in vinyl distribution, can regulate and control the polymerization degree, the vinyl content and the end group, and is wide in application range.

The present invention provides a 4-vinylguaiacol oxygenase mutant for synthesizing vanillin, and an engineered bacterium thereof. The 4-vinylguaiacol oxygenase mutant is an enzyme having the sequence as shown in SEQ ID NO. 1, which exhibits a double-site mutation of D27P / T216M, D27P / M351F, D27P / Y156D, M351F / Y156D, T216M / Y156D or T216M / M351F, or a single-site mutation of T216M, T216L, S280M, G307P or M351F, and can be used for catalyzing 4-vinylguaiacol to generate vanillin.

The invention relates to a preparation method of a high-lithium-affinity vinylene covalent organic framework material serving as a lithium metal negative electrode interface protective layer. The method comprises the following steps: firstly, by utilizing a simple hydrothermal synthesis method, taking 1, 3, 5-trimethyl-2, 4, 6-triazine (TMT) and 2, 2-bipyridine-5, 5-diformaldehyde (BPY) as monomers, and carrying out Aldol condensation reaction to synthesize a covalent organic framework material connected by a vinylene bond, which is named as viCOF-bpy; the electrochemical performance of the material is verified by modifying the surface of a copper pole piece with the viCOF-bpy material and then assembling a battery. The lithium-loving group on the material skeleton can promote the migration of lithium ions, and the vinylidene has very strong chemical stability, so that the electrochemical performance of the lithium metal battery can be effectively improved.

The invention relates to a preparation method of an active oxygen responsive microneedle with a separable base, which comprises the following steps: mixing 3-(acrylamide) phenylboronic acid, epigallocatechin gallate and N-vinyl pyrrolidone, and standing to obtain an E-A compound solution; dissolving cyclosporine and an initiator in the E-A compound solution to obtain a microneedle precursor solution; placing the microneedle precursor solution on the surface of a microneedle mold, and performing in-situ polymerization to form a microneedle body; paving a mixed aqueous solution of poly (N-isopropylacrylamide-n-butyl acrylate) and polyvinyl alcohol on the microneedle mold substrate forming the microneedle body, and drying to form a microneedle substrate; and stripping the microneedle body with the microneedle substrate from the microneedle mold to obtain the active oxygen responsive microneedle with the separable base. According to the product prepared by the preparation method, drug release can be adjusted by sensing ROS of an inflammation part, deep penetration of the drug is realized, controllable separation between a backing layer and a needle head can be realized, and discomfort of a patient is reduced.

The invention provides a cronobacter malonate strain and application thereof, the strain is preserved in China Center for Type Culture Collection on January 15, 2025, the preservation date is January 15, 2025, and the preservation number is CCTCC M 2025146. The strain has excellent capability of producing 4-vinyl guaiacol, and the yield in a sorghum juice fermentation culture medium is 2.70 + / -0.15 mg / L; meanwhile, the strain can resist ferulic acid and has good capability of converting ferulic acid to generate 4-vinyl guaiacol, and when 0.1% (w / w) of ferulic acid is added into a fermentation culture medium, the content of 4-vinyl guaiacol reaches 2.68 + / -0.04 g / L. The strain is applied to production of Maotai-flavor liquor, the content of 4-ethyl guaiacol in raw liquor reaches 3.20 + / -0.26 mg / L and is remarkably increased by 223.23% (P is smaller than 0.01) compared with the content of 4-ethyl guaiacol without the strain, the Maotai flavor is prominent through sensory evaluation, the flower, fruit and burnt flavor is obvious, and the strain has important significance on improvement of the health quality of the liquor.

The invention relates to the field of organic chemical synthesis, in particular to a preparation method of chiral 6-methyl nicotine. The invention provides a synthesis method of single chiral 6-methyl nicotine, which comprises the following steps: taking methyl 6-methyl nicotinate (compound I) and N-vinyl pyrrolidone (compound II) as initial raw materials, and sequentially carrying out condensation reaction, hydrolysis reaction, cyclization reaction, chiral reduction reaction and aminomethylation reaction to finally obtain the target product chiral 6-methyl nicotine (R or S compound VI). According to the synthetic route, the 6-methyl nicotine with two configurations of R and S can be prepared respectively, and the purity of the product can reach 99.5% or above. The synthesis method is simple in process, high in yield and suitable for industrial large-scale production.

The invention discloses a fluopyram preparation method, which comprises: S1, carrying out a heating reaction on 2-vinyl-3-chloro-5-trifluoromethylpyridine, ammonia water, a catalyst and a solvent, carrying out reduced pressure distillation after the heating reaction to recover the solvent so as to obtain a residue, and adding dichloromethane and triethylamine to the residue so as to obtain a reaction liquid; and S2, dropwise adding o-trifluoromethyl benzoyl chloride into the reaction liquid in an ice bath, then removing the ice bath, stirring at the room temperature, adding water into the reaction liquid obtained in the step S1, extracting an organic layer, drying with anhydrous magnesium sulfate, recovering the solvent under reduced pressure, and performing vacuum drying to obtain the fluopyram. The method has the advantages of high reaction yield, high product purity, recyclable and reusable solvent, simple and mild production process, and suitableness for mass production.

The invention provides a pharmaceutical composition, a rod core, an implant and a preparation method and application thereof. The pharmaceutical composition comprises the following components in parts by weight: 1-1000 parts of active pharmaceutical ingredients; 100 parts of R-vinyl silicone rubber; hydrogen-containing silicone oil; 0.000002 to 1 part of a catalyst; r in the R-vinyl silicone rubber is substituted or unsubstituted C1-C5 straight-chain alkane or branched alkane, and substituted or unsubstituted C6-C20 aromatic hydrocarbon; the content of vinyl in the R-vinyl silicone rubber is 0.10 to 0.50 mol%; the content of Si-H groups in the hydrogen-containing silicone oil is 0.15 to 1.6 mol percent; the molar ratio of Si-H group in the hydrogen-containing silicone oil to vinyl in the R-vinyl silicone rubber is (0.5-20): 1. The implant provided by the invention can reduce drug loss and sudden release phenomenon, the drug release is more stable, and the production speed is greatly increased.

The invention relates to the technical field of corrosion inhibitors, and discloses a preparation method of a modified imidazoline corrosion inhibitor, which comprises the following steps: carrying out quaternization reaction on tertiary amine group in an imidazoline intermediate and chlorine in benzyl chloride to generate quaternary ammonium salt, introducing hydroxyl, and continuing to carry out esterification reaction with boric acid group in 4-aminophenylboronic acid to obtain the modified imidazoline corrosion inhibitor. The modified imidazoline corrosion inhibitor is prepared by the following steps of: firstly, introducing amino groups, then carrying out amidation reaction with acyl chloride groups in 4-vinyl benzoyl chloride, introducing alkenyl groups, and finally carrying out click reaction with sulfydryl groups in DSB-TA, so as to generate the modified imidazoline corrosion inhibitor. The modified imidazoline corrosion inhibitor disclosed by the invention has a relatively good corrosion inhibition effect.

The present application provides modified polyvinylidene fluoride and a preparation method therefor, an active material composition, a positive electrode sheet, and an energy storage device. The modified polyvinylidene fluoride provided by the present application is a copolymer of vinylidene fluoride and 4-vinyl-4'-substituent-bis-benzenesulfonimide lithium, and the mass fraction of the 4-vinyl-4'-substituent-bis-benzenesulfonimide lithium in the modified vinylidene fluoride ranges from 2% to 10%. The modified vinylidene fluoride not only has good binding power, but also has relatively strong lithium ion conduction capability, thereby improving the rate performance of the energy storage device.

The invention relates to the technical field of oilfield exploitation, and discloses a preparation method of N-vinyl amide. The method comprises the following steps: under a heating condition, enabling a structure as shown in a formula (1) and a structure as shown in a formula (2) to be in contact and react, wherein in the formula (1), R1 is H or alkyl of C1-C8, and R2 is hydrogen or alkyl of C1-C4; in the formula (2), R3 is H or C1-C8 alkyl, and M is H, Na, K or Cs. The method has the advantages of low reaction temperature, simplicity in operation, small corrosion to equipment, high product yield and excellent purity.

A silicone hydrogel contact lens formulation comprising [a] at least 40 wt% of a polymerisable siloxane, [b] at least 30 wt% of hydrophilic N-vinyl amide monomer, such as vinyl-N-methyl acetamide (VMA), N-vinyl pyrrolidone (NVP), N-vinyl formamide, or N-vinyl acetamide; [c] triphenylphosphine (TPP) and [d] 1,4-bis[(2-methacryloxyethyl)amino]-9,10-anthraquinone (RB247). The contact lens formulation can further comprise an anthraquinone blue tinting agent, a benzophenone UV-absorbing agent and / or a benzotriazole HEVL absorber to stabilise the silicone hydrogel contact lens formulation.

The invention provides a concrete water reducing agent and a preparation method thereof, and belongs to the technical field of water reducing agents. Adding the modified chitin, 1-vinyl-3-butylimidazolium trifluoromethanesulfonate, a silane coupling agent with double bonds, methacrylic acid, trans-butenedioic acid and an initiator into dimethylformamide, heating and stirring for reaction, removing methylbenzene under reduced pressure, and performing alkali washing and alcohol washing to obtain the concrete water reducing agent. The modified chitin is prepared by modifying chitin modified by sodium sulfonate and acrylic acid with tannic acid. Modified chitin, 1-vinyl-3-butylimidazolium trifluoromethanesulfonate, a silane coupling agent with double bonds, methacrylic acid and trans-butenedioic acid are copolymerized to prepare the polycarboxylate superplasticizer, molecules of the polycarboxylate superplasticizer are of a comb-shaped structure, a main chain of the polycarboxylate superplasticizer is provided with a plurality of active groups with high polarity, and a side chain of the polycarboxylate superplasticizer is provided with hydrophilic active groups. The water-reducing agent has the characteristics of low doping amount, high water-reducing rate, high reinforcing effect, high plasticity retaining property and volume stability, and has wide application prospects.

The invention relates to the technical field of tobacco smoke analysis, and discloses a gas sensor for detecting the content of 3-vinylpyridine in real time and a preparation method of the gas sensor. In order to realize accurate detection of tobacco smoke in the environment, 3-vinylpyridine in environmental gas is taken as a detection object, a SnO2 nanofiber material is further taken as a gas sensitive element, the detection sensitivity of the 3-vinylpyridine is remarkably improved, the SnO2 nanofiber material is arranged on the heating substrate, and the gas sensitive element is arranged on the heating substrate. The gas sensor generates a resistance change signal which linearly changes along with the change of the content of 3-vinylpyridine, so that the environmental tracing of the tobacco smoke is realized. Therefore, the invention provides the gas sensor with high sensitivity and high accuracy for tobacco smoke environment tracing.

The invention discloses a method for synthesizing 2-vinylpyridine by a one-pot method, which comprises the following step: by taking 2-methylpyridine and paraformaldehyde as raw materials and water as a solvent, synthesizing the 2-vinylpyridine by a one-pot reaction under the catalysis of a basic catalyst. According to the invention, 2-methylpyridine and paraformaldehyde are taken as initial raw materials, the raw materials are simple and easy to obtain, the production cost is reduced, and water is taken as a solvent, so that the use of a large amount of organic solvents is avoided, and the influence on environmental pollution is small. In the reaction, a basic catalyst such as triethylamine is used as a catalyst, a small amount of sodium hydroxide solid is added in the reaction process, the basic catalyst enables the whole system to be in an alkaline environment, and sodium hydroxide improves the depolymerization efficiency of paraformaldehyde and promotes the dehydration process of the reaction, so that the selectivity and yield of 2-vinylpyridine are improved.

The invention relates to the technical field of water treatment, in particular to a rare earth composite antibacterial scale inhibitor and a preparation method thereof.The preparation method comprises the steps that glycidyl methacrylate, vinylphosphonic acid, N-vinylthiourea and acrylic acid are mixed, a mixed solvent of deionized water and ethyl alcohol is added, nitrogen is introduced after the mixture is stirred and dissolved, azodiisobutyronitrile is added, the mixture is stirred at the constant temperature for a reaction, and the rare earth composite antibacterial scale inhibitor is obtained; the preparation method comprises the following steps: preparing a quadripolymer solution, adding trimethylamine hydrochloride into the quadripolymer solution, carrying out heating and stirring reaction, adjusting the pH value to be neutral to obtain a cationized copolymer solution, dropwise adding the cationized copolymer solution into a cerous nitrate solution, carrying out stirring reaction at room temperature, carrying out centrifugal washing, and carrying out freeze drying to obtain the rare earth composite antibacterial scale inhibitor. The prepared antibacterial scale inhibitor is remarkable in effect, metal ions can be combined in scale inhibition, growth of scale crystals is prevented, the rare earth ions and the copolymer are synergistically antibacterial, and the antibacterial scale inhibitor is durable, stable, good in dispersity and capable of adapting to complex environments.

The present invention relates to a vinyl pyrrolidone copolymer of N-vinyl pyrrolidone and a maleic acid comonomer wherein the vinyl pyrrolidone copolymer is functionalized with a benzophenone substituent (BP) wherein the amount of maleic acid in the vinyl pyrrolidone copolymer is less than 1 mol%, preferably from 0.1 to 0.95 mol%, further preferably from 0.1 to 0.90 mol%, more preferably from 0.1 to 0.85 mol%, more preferably from 0.2 to 0.88 mol%, and the amount of N-vinyl pyrrolidone is less than 1 mol%, preferably from 0.1 to 0.95 mol%, further preferably from 0.1 to 0.90 mol%, more preferably from 0.1 to 0.85 mol%, more preferably from 0.2 to 0.88 mol%. The invention relates to the technical field of organic solvents, in particular to a method for preparing the organic solvents, which comprises the following steps of: preferably, 1-3mol%, more preferably, 0.3-0.88 mol%, more preferably, 0.4-0.88 mol%, even more preferably, 0.5-0.85 The vinyl pyrrolidone copolymer of the present invention is particularly suitable for use in coatings of medical devices and / or medical aids. Thus, the invention also relates to a composition comprising a vinyl pyrrolidone copolymer and optionally a cross-linking agent, and a medical device having a coating comprising a cross-linked vinyl pyrrolidone copolymer and optionally a cross-linking agent.

The invention relates to a random copolymer of structure (A) comprising, a carboxylic acid bearing repeat of structure (I), a 4-vinylbenzocyclobutene derived repeat unit of structure of structure (II), a styrenic repeat unit of structure (III), an alkyl acrylate or alkyl 2-methylenealkanoate derived repeat unit of structure (IV), a hydroxy functionalized alkyl acrylate or alkyl 2-methylenealkanoate derived repeat unit of structure (V), and two end groups as shown in structure (A) one of which is H and the other is a methyl moiety substituted with Rr, Rr1 and Rr2, wherein Rr1, is a C-1 to C-8 alkyl, Rr2 is selected from a C-1 to C-8 alkyl, a C-1 to C-8 alkylene hydroxy moiety (-alkylene-OH), a C-1-C-8 alkylenecarboxylic acid moiety (-alkylenne-CO2H), or a benzylic alcohol comprising moiety of structure (B), Rr is a cyano moiety (—CN) or a carbonylalkyl moiety (—C(═O)—Ri), wherein Ri is a C-1 to C-8 alkyl or an aryl moiety.

The present application belongs to the field of rare earth separation, and particularly discloses a method for separating heavy rare earth ions. In the method, a vinyl complexing agent including at least one of vinyl phosphonic acid, vinyl sulfonic acid, vinyl acetic acid or 4-vinyl benzyl chloride is used to selectively complex heavy rare earth ions in an aqueous phase, so as to obviously increase the distribution coefficient between different heavy rare earth ions. Then, the aqueous phase containing the complex of heavy rare earth ions is subjected to extraction separation of different heavy rare earth ions with an organic phase containing an extractant, so as to achieve the purpose of improving the separation efficiency.

The invention provides a temperature-resistant salt-resistant water-based drilling fluid filtrate reducer based on modified humate and a preparation method of the temperature-resistant salt-resistant water-based drilling fluid filtrate reducer, and belongs to the field of oilfield chemistry. A temperature-resistant salt-resistant monomer, ethylene phosphoric acid, a solubility improving monomer and an adsorbability improving monomer are grafted to humate, the solubility improving monomer is at least one of vinyl pyrrolidone, hydroxyethyl acrylate, N-vinylformamide and hydroxypropyl methacrylate; and the adsorbability improving monomer is at least one of KH570 and KH151. The filtrate reducer disclosed by the invention has excellent temperature-resistant and salt-resistant effects, shear resistance and filtrate reduction performance.

The present invention discloses the application of a water-soluble and positively charged fluorescent probe TPA-3Py for the detection of sodium heparin. TPA-3Py is obtained by covalently connecting three methylated vinylpyridines to the three arms of a triphenylamine molecule respectively. Heparin can induce the aggregation-induced emission effect of this fluorescent molecule. With the increase of the heparin content, the fluorescence intensity increases significantly, showing a good fluorescence turn-on response, overcoming the deficiency that the fluorescence probe quenches due to aggregation during the detection of heparin in the prior art. When a 10 μM aqueous solution of TPA-3Py is used for the detection of heparin, a stable fluorescence intensity is achieved within 5 minutes, the linear range is 0 - 6.14 mg / L (R<supgt;2< / supgt> = 0.9938), the lowest detection limit is 49.53 ng / mL, and the quantum yield reaches 4.85%. For the detection of sodium heparin, the TPA-3Py probe adopted in the present invention overcomes the quenching phenomenon caused by aggregation and exhibits a significant AIE effect. The fluorescent probe TPA-3Py for the detection of sodium heparin in the present invention has high sensitivity, high fluorescence intensity, rapid response and stable signal. The fluorescent molecular structure of TPA-3Py is simple, and the detection method is simple and easy to implement, which is worthy of popularization and application in the determination of the sodium heparin content.