The invention discloses a traditional Chinese medicine preparation for lowering high blood pressure, high blood sugar, high cholesterol, high uric acid and maintaining vigor. The traditional Chinese medicine preparation is prepared from the following traditional Chinese medicines: semen coicis, semen cassia, lotus leaf, plantain herb, gynostemma pentaphyllum, puerarin, rhizoma atractylodis macrocephalae, corn stigma, smilax glabra, chrysanthemum morifolium ramat and American ginseng. The preparation method of the traditional Chinese medicine preparation for lowering high blood pressure, high blood sugar, high cholesterol, high uric acid and maintaining vigor comprises the following steps: 1 adding water and decocting the traditional Chinese medicines twice, respectively filtering detection which is decocted twice, and merging and concentrating filtrate; and 2 adding xylitol to the concentrated liquid, and mixing into a hanging flag shape, namely the product of the traditional Chinese medicine preparation for lowering high blood pressure, high blood sugar, high cholesterol, high uric acid and maintaining vigor. According to the traditional Chinese medicine preparation for lowering high blood pressure, high blood sugar, high cholesterol, high uric acid and maintaining vigor, disclosed by the invention, the semen coicis has the efficacies of tonifying the spleen, excreting dampness, removing numbness, and relieving diarrhea; the semen cassia has the efficacies of clearing the liver, improving vision, and loosening the bowels to relieve constipation, so as to achieve the effects of lowering uric acid, high blood sugar, high cholesterol and high blood pressure. According to the preparation method of the traditional Chinese medicine preparation for lowering high blood pressure, high blood sugar, high cholesterol, high uric acid and maintaining vigor, disclosed by the invention, the effective components of the medicine can be effectively extracted by decoction twice, and the prepared plaster is convenient to use.