32results about How to "Coagulation does not occur" patented technology

The invention relates to a liquid-phase CO2 methanation catalyst, a preparation method and application of the catalyst. The liquid-phase CO2 methanation catalyst comprises amphipathic ionic liquid and metal active components dispersed in the amphipathic ionic liquid in the state of stable colloid, the grain sizes of the metal active components range from 0.5nm to 20nm, the spherical metal active components include a first metal active component and a second metal active component, the first metal active component includes nickel, the second metal active component includes one or mixture of more than one of lanthanum, cerium, molybdenum, ruthenium, ytterbium, rhodium, palladium, platinum, potassium and magnesium, and the molar ratio of the first metal active component to the second metal active component is 10:0.1-2. The metal active components in the liquid-phase CO2 methanation catalyst are small in grain size, narrow in distribution, wide in application prospect, easy to separate and recyclable, CO2 methanation of low-temperature liquid phase can be realized at the temperature of 100-200 DEG C, the liquid-phase CO2 methanation catalyst has excellent low-temperature catalytic activity, methane selectivity and heat stability, and the preparation method is simple and practicable, low in cost and easy in popularization.

The invention discloses small-size gadolinium-polyphenol polymer nano-particles and a preparation method and application thereof. In a mixed solvent containing polyvinylpyrrolidone, under the alkalescent condition, polyphenol is covalently cross-linked into polyphenol oligomer with an aldehyde cross-linking agent, then metal gadolinium salt is added, and the metal gadolinium salt and the polyphenol oligomer are cross-linked through metal-organic ligand to form the small-size gadolinium-polyphenol polymer nano-particles. In the reaction process, the size of the gadolinium-polyphenol polymer nano-particles is controlled by adjusting the use level of the polyvinylpyrrolidone. The method is easy to operate, low in synthesis process and high in process controllability, and the size and composition of the small-size (10-100 nm) metal-polyphenol polymer nano-particles can be precisely regulated and controlled. Due to the fact that functional and targeted modification of the polymer nano material are easy, the small-size gadolinium-polyphenol polymer nano-particles have wide application prospects in the fields of medical imaging, drug delivery, photo-thermal treatment, biosensing and the like.

The invention relates to a metal surface alloying method in which a non-uniform heat source promotes convection of a molten pool, comprising the following steps: 1) using a first heat source to heat and melt the metal surface to form a molten pool; 2) alloying gas entering the molten pool for reaction Compounds with high melting points are generated, and the compounds tend to solidify to form a solidified layer. The second heat source is used to heat the area where the compound is located to ensure that the compound does not solidify, promote the convection of the molten pool, and form an alloyed layer with uniform composition and structure. The first heat source and The second heat source is arranged in sequence along the moving direction of the heat source, and the power density of the second heat source is greater than that of the first heat source; 3) Along the moving direction of the heat source, the first heat source and the second heat source move as a whole, and the molten pool solidifies to form an alloy layers. The above-mentioned non-uniform heat source is used for laser gas alloying of the metal surface, and finally an alloyed layer with better structure and performance is obtained.

The invention discloses a leakage plugging method for an oil pipe, which belongs to the safety field of oil and gas wells. The method includes: determining the position of the leak point on the oil pipe; setting the oil pipe with a plug, the plug being located below the leak point in the length direction of the oil pipe; squeezing a plugging agent from the oil pipe into the leak point, and make the plugging agent solidify in the leak point during the extrusion process; take out the plug. In the invention, the oil pipe is first set with a plug, and the leakage plugging agent is squeezed into the leakage point channel from the oil pipe to block the leakage point. The whole process does not need to take out the oil pipe and does not change the structure of the pipe string. The entire plugging construction operation is simple, and the construction time is only It takes a few days, the cost is low, and the risk is low.

The invention belongs to the technical field of engineering construction and specifically discloses a grouting pipe bit for road construction. The grouting pipe bit comprises a drill bit main body, wherein a first chamber is formed in the drill bit main body; a high-pressure runner which is connected with the first chamber is formed on the drill bit main body; a high-pressure nozzle is arranged inthe high-pressure runner; a drill tip is arranged on the lower part of the drill bit main body; a second chamber is formed in the drill bit; the first chamber is connected with the second chamber; anauxiliary grouting hole which is connected with the second chamber is formed on the drill tip; a hydraulic control cut-off unit and a grout backflow unit are arranged in the second chamber. The grouting pipe bit with such a structure is capable of solving the problem of pipeline blocking caused by the stagnation and solidification of residual grout in the channel during high / low pressure conversion process.

The invention relates to cryopreservation protection liquid for Wharton jelly tissues of a human umbilical cord. The cryopreservation protection liquid comprises 5-10 percent of a permeable cryoprotectant, 1-5 percent of a non-permeable cryoprotectant, 10-20 percent of a knockout serum replacement and 70-80 percent of a serum-free basal culture medium. The invention also discloses a preparation method of the cryopreservation protection liquid. The preparation method specifically comprises the steps of (1) precooling the serum-free basal culture medium, the non-permeable cryoprotectant and the knockout serum replacement, mixing and uniformly shaking; (2) adding the permeable cryoprotectant; and (3) performing refrigeration under a temperature condition of 2-6 DEG C for more than 30min. The invention also discloses a cryopreservation method for the Wharton jelly tissues of the human umbilical cord by the cryopreservation protection liquid. The cryopreservation method comprises the following steps of (1) pretreating the umbilical cord; (2) peeling off the Wharton jelly tissues; and (3) cryopreserving the Wharton jelly tissues of the human umbilical cord. The cryopreservation protection liquid and the cryopreservation method which are used for treating the Wharton jelly tissues of the human umbilical cord have the advantages that injury to umbilical cord mesenchymal stem cells in a cryopreservation process can be alleviated, so that the activity and the clinical use safety of the umbilical cord mesenchymal stem cells are guaranteed.

The water lettuce plant viscosity reducer and production method of the present invention belong to the petroleum field. The water lettuce plant viscosity reducer contains the following components, and the weight percentages of each component are as follows: biochemical water lettuce plant fermentation liquid 20-65%, surface Active agent 5-25%, liquid silicone 2-15%, mixed for emulsification treatment, the present invention has a good visbreaking effect on petroleum crude oil and stable performance, and the visbroken crude oil basically does not occur during transportation and storage. The solidification phenomenon solves the problem of secondary visbreaking and multiple dehydration before oil refining, and reduces the cost of oil refining. At the same time, because the present invention adopts the mechanism of biological visbreaking, it avoids the large use of organic matter and overcomes the problems caused by the use of organic matter. It has high economic and social benefits.

The invention discloses a preparation method of a CT imaging molecular probe of folate receptor targeted tumors, which comprises the following steps: dissolving folic acid which is used as a wrapping agent in a solution which contains gold ions and is used for preparing nanogold, adjusting the pH to 7.0-7.5 to obtain a mixed solution, wherein the molar ratio of folic acid to gold ions is 1:2-6; adding a reducing agent into the mixed solution, rapidly stirring and reacting for at least 1 hour, naturally cooling after the reaction, performing dialysis to remove unreacted parts so as to obtain the nanogold coated by folic acid. The nanogold coated by folic acid FA-GNP prepared in the invention has high attenuation capability for X ray, and can be used as a CT imaging contrast agent; the FA-GNP can provide CT images with high contrast for tumors.

The invention relates to a medical polyurethane elastic fiber with biocompatibility and a preparation method thereof. The preparation method comprises the following steps: 1) adding polyglycol A, aliphatic diisocyanate B, chain extender glycol C, a catalyst, an auxiliary additive and the like directly into a twin-screw reactor after metering for melting, mixing and slicing to prepare a polymer P1;2) mixing and reacting modified aliphatic diisocyanate B' with polyglycol A to generate a prepolymer P2; 3) after the polymer P1 is fused and extruded and fully mixed with the prepolymer P2 in a certain proportion in a static mixer, distributing the mixture to a spinneret plate through a melt metering pump; and 4) spinning the polyurethane elastic fiber through a spinning box, a side blowing cooling device, a spinning tunnel, false twisting, oiling and a silk guide roller. The polyurethane elastic fiber prepared by the method provided by the invention has excellent biocompatibility.

The invention relates to a preparation method of naphthol AS. The method comprises a condensation process, an alkali cooking process, a filtration process, a drying process and a tail gas recycling process, wherein the condensation process comprises the following steps: 1) adding chlorobenzene and an organic solvent into a suspension pot; 2) after stirring and mixing, adding 2-hydroxy-3-naphthoic acid and an oil soluble ionic dispersant, stirring and adding aniline into the suspension pot; 3) filling materials in the suspension pot into a condensation reaction kettle and dropwise adding mixed liquid of phosphorus trichloride; 4) after the completion of dropwise adding of the mixed liquid of the phosphorus trichloride, heating with steam to obtain condensation materials. The preparation method of the naphthol AS provided by the invention has the benefits that a produced naphthol AS product has good quality and high yield; as the oil soluble ionic dispersant and the organic solvent are added in the condensation process, the dispersion of particles in suspension liquid is more uniform, and the coagulation phenomena cannot occur, so that the condensation process reaction is complete, the time of the condensation process is shortened, and the economic benefit is improved.

The invention provides a drug-loaded nano material and a preparation method thereof, the drug-loaded nano material comprises drug particles with a mass ratio of (0.01-2):1 and a polydopamine modifiedwith a thiolated hydroxyethyl starch, the periphery of the polydopamine is modified with the thiolated hydroxyethyl starch, the peripheral regions of polydopamine nanoparticles are uniformly coated with the drug particles, and the encapsulation efficiency of the drug particles in the periphery regions of the polydopamine is 30% to 100%; the preparation method comprises the following steps: 1, a mixture of the thiolated hydroxyethyl starch and the polydopamine is reacted under basic conditions to obtain the polydopamine modified with the thiolated hydroxyethyl starch; and 2, 1 part by weight ofthe polydopamine modified with the thiolated hydroxyethyl starch and less than 2 parts by weight of the drug particles are mixed for reaction to obtain the drug-loaded nano material. The preparationmethod of the drug-loaded nano material has simple operation and easy regulation of conditions, and the prepared drug-loaded nano material has strong loading ability and good biodegradability.