The invention discloses a sebum-like membrane component and a preparation method thereof. A sebum-like membrane comprises the following components: triglyceride, wax, a squalane-like component and cholesterin / ester in a mass ratio of (50-70): (10-30): (10-30): (1-10). Substances similar to a skin component structure form a sebum-like membrane component so as to apply on skin, wherein triglyceridein the sebum-like membrane component accounts for 50-70% by weight, the triglyceride is at least one kind of grease selected from vegetable grease, and the wax is at least one kind of wax selected from Brazil wax palmitate wax, white beeswax, white pyrophyllite wax, beeswax, bitter orange flower wax and candelilla wax. The invention discloses a sebum-like membrane component and a preparation method thereof, the safety of the components is ensured, no harm is caused to the health of the skin, meanwhile, the interior of the skin is better explored, the sebum-like membrane component acts on the skin, so the skin is moistened, fine and soft, the stable health state of the skin is better maintained, and then the skin is kept in the youth and vitality state.