113results about How to "Small liquid holding capacity" patented technology

The invention discloses a method for preparing polymethoxy dimethyl ether through reaction and rectification of a fixed bed. The method comprises the following steps: (1) preheating trioxymethylene, uniformly mixing the preheated trioxymethylene and methylal, and feeding the trioxymethylene and the methylal which are uniformly mixed into a fixed bed reactor for an etherification reaction; (2) feeding materials after the etherification reaction into a reaction rectifying tower for the reaction and the rectification, and discharging PODE2-8 from the tower bottom of the reaction rectifying tower; (3) transporting the PODE2-8 to a dewatering tower loaded with a 3A molecular sieve for dehydration, then transporting the dehydrated PODE2-8 into a first refining tower, transporting materials which are discharged from the tower bottom of the first refining tower into a second refining tower, discharging PODE3-5 from the tower top of the second refining tower, and discharging PODE6-8 from the tower bottom of the second refining tower. When the method disclosed by the invention is used for preparing the PODE3-8, the yield of the polymethoxy dimethyl ether can reach 95%, wherein the products of the PODE3-8 can reach 80%-95%, and after refinement, the PODE3-5 of which the quality purity reaches 99.9% can be obtained.

The invention discloses a riser spiral-flow type falling-film evaporator for a refrigerating air conditioner. The riser spiral-flow type falling-film evaporator comprises a shell, a refrigerant steam conveying pipe bundle, a falling-film evaporation pipe bundle, a damping hole plate and a spiral baffle plate, wherein the refrigerant steam conveying pipe bundle is arranged in the center in the shell and along the circumferential direction of the inner all of the shell, the falling-film evaporation pipe bundle is surrounded by the refrigerant steam conveying pipe bundle, the refrigerant steam conveying pipe bundle and the falling-film evaporation pipe bundle are both vertically arranged inside the shell, the upper part of an inlet of the falling-film evaporation pipe bundle is horizontally provided with the damping hole plate, the spiral baffle plate is fixed inside the shell and spirally arranged along a vertical direction, and is provided with through holes allowing the refrigerant steam conveying pipe bundle and the falling-film evaporation pipe bundle to pass through, an ejector is arranged between a refrigerant outlet pipe and a refrigerant inlet pipe, the inlet of the falling-film evaporation pipe bundle is provided with a flow guiding nozzle which has an outer diameter smaller than the inner diameter of the falling-film evaporation pipe bundle and is sealed at two ends, and the flow guiding nozzle is provided with a circular ring with three chutes formed along a circumferential direction uniformly. The riser spiral-flow type falling-film evaporator has the characteristics of small heat transfer temperature difference, high heat transfer coefficient, large evaporative power of unit area capable of preventing dry evaporation, low manufacture cost, less liquid holdup, small floor area and high safety.

The invention relates to a rapid continuous flow synthesis process of fluoroethylene carbonate and an integrated continuous flow reactor for realizing the process. The continuous flow synthesis process is characterized in that a raw material to be fluorinated and fluorine gas are used as reactants, and are continuously and successively subjected to steps of mixed dispersion, fluorination reaction,gas-liquid separation, so as to obtain the fluoroethylene carbonate; and the synthesis process is carried out in the integrated continuous flow reactor, the raw material to be fluorinated and the fluorine gas are continuously added to a feed inlet of the integrated continuous flow reactor, and the fluoroethylene carbonate is continuously obtained from a discharge port of the integrated continuousflow reactor with the reaction time equal to or less than 600 s. The process is a rapid, safe, efficient, highly versatile and easy for mass production continuous synthesis process of the fluoroethylene carbonate.

The invention which relates to the field of structured fillers concretely relates to a cheap and high efficiency rectification filler and a preparation method thereof. The filler which is suitable for a rectification operation under a temperature of less than 300 DEG C is formed by stacking filler unit plates with corrugated shapes, the filler unit plates are foamed resin-based filler unit plateswith three-dimensional connected network structures, the foam pore sizes are between 10PPi and 80PPi, and the volume fraction is controlled between 10% and 80%. A plurality of the filler unit plates are stacked, the filler unit plates of the odd-numbered layers have a consistent channel direction, and the filler unit plates of the even-numbered layers have a consistent channel direction, and an angle between the channel direction of the filler unit plates of the odd-numbered layers and the channel direction of the filler unit plates of the even-numbered layers is 30-170 DEG; a corrugation angle between a corrugation parallel direction and a vertical direction of a filler disc is 15-85 DEG, corrugations of adjacent filler unit plates have a same angle and opposite directions; and the filler unit plates are bonded after being stacked, and are subjected to a heat treatment to obtain the filler. The foamed resin-based structured filler unit plates of the invention allows the three-dimensional network connectivity characteristic of a polyurethane foamed plastic template to be kept, and has the characteristics of large specific surface area, thin wall, cheapness, high chemical stabilityand the like.

The invention provides a continuous synthesis method for 2-methyl-5-nitroimidazole. The 2-methyl-5-nitroimidazole is synthesized in a micro-channel reactor. The synthesis method provided by the invention can realize continuous synthesis, is safe and stable in production process, extremely short in reaction time and high in yield, and can reduce the usage amount of concentrated sulfuric acid and lower cost.

The invention provides a method for synthesizing 3-fluoro-4-(4-morpholinyl)aniline by using a micro-channel reactor. The micro-channel reactor comprises a preheating module group composed of one or more parallely-connected preheating modules and a reaction module group composed of one or more tandemly-connected reaction modules, wherein the preheating module group is series connection with the reaction module group. The method comprises the following steps: separately preheating difluorobenzene, concentrated nitric acid and concentrated sulfuric acid, then subjecting the preheated difluorobenzene, concentrated nitric acid and concentrated sulfuric acid to a reaction in the reaction module group and carrying out treatment so as to obtain 3,4-difluoronitrobenzene; dissolving 3,4-difluoronitrobenzene in an organic solvent, adding organic base, dissolving morpholine in the organic solvent, carrying out preheating, allowing the obtained solution to enter the reaction module group for a reaction and carrying out treatment so as to obtain 4-(2-fluoro-4-nitrophenyl)morpholine; and dissolving 4-(2-fluoro-4-nitrophenyl)morpholine in ethyl acetate, adding a catalyst, carrying out preheating, allowing the obtained solution and hydrogen to enter the reaction module group for a reaction and carrying out treatment so as to obtain 3-fluoro-4-(4-morpholinyl)aniline. The method has the advantages of low energy consumption, high yield, high product purity, safety, flexibility, etc.

The invention discloses a multichannel-type composite demister and a demisting method. The multichannel-type composite demister comprises a demister case and a cylindrical structure enclosed by a baffle plate and arranged in the demister case with axial direction, the inner part of the cylindrical structure is divided into a filling material chamber and an intermediate rectification chamber; a second baffle plate and a third baffle plate are arranged between an upper end of the cylindrical structure and the demister case as well as a lower end of the cylindrical structure demister case; a support plate is arranged between central section of the outer wall of the cylindrical structure and the demister case, a bottom circulation chamber is formed by a cavity defined by the second baffle plate and the support plate, a top circulation chamber is formed by a cavity defined by the support plate and the third baffle plate; air flow is introduced into the bottom circulation chamber, an intermediate rectification chamber, a filling material chamber and the top circulation chamber from the bottom of the demister case in order, and is discharged from the top of the demister case. By employing a composite demisting effect with combination of multichannel separating, baffle plate inertia separating and filling material separating, little liquid drop can be removed, so that the demister can better solve the raining or gypsum rain phenomenon of a chimney.

The invention discloses a method for preparing an aryl formic acid compound with a microchannel continuous flow reactor. The method comprises the following steps: with methyl aromatics represented bythe formula (I) as a raw material, a mixture of cobalt salt, manganese salt and iron salt as a ternary complex catalyst, hydrogen peroxide with mass concentration of 30% as a cocatalyst, and acetonitrile or acetic acid as an organic solvent, uniformly mixing to form a homogeneous solution, pumping the homogeneous solution into the microchannel continuous flow reactor through a metering pump, reacting at 25 to 150 DEG C in an oxygen atmosphere of 0.5 to 10 MPa for 4 to 100 seconds to obtain a reaction mixture, and carrying out post-treatment to obtain the aryl formic acid compound represented by the formula (II). According to the invention, with cleaning agents such as oxygen and hydrogen peroxide as oxidants and cocatalysts, by-products toxic and harmful to the environment are reduced, thesystem is greener and cleaner, the reaction can be continuously carried out, the production efficiency is high, and industrialized amplified production is facilitated.

The invention discloses a continuous flow preparation method of diethyl methyl phosphite, which comprises the following steps: continuously adding ethanol and methyl phosphorus dichloride into a feedport of a continuous flow reactor, and continuously obtaining diethyl methyl phosphite at a discharge port of the continuous flow reactor. The method has the advantages of small liquid holdup, safe and efficient production process, solving of the problems of long reaction time and low efficiency in kettle type reaction, high product yield and purity, and simple and efficient process operation.

The invention provides a method for synthesizing lenalidomide, belongs to the field of anti-tumor and anti-leukemia medicines in organic synthesis, and particularly relates to the method for synthesizing lenalidomide. To solve the problems of low yield, low purity, environmental pollution caused by massive harmful waste, excessive cost for environment-friendly treatment, easily occurred risk of violent explosive, degradation caused by long reacting time at high temperature and low catalyst recycling frequency in a traditional lenalidomide synthesis reaction, the method comprises the following steps: 1, adding a lenalidomide precursor nitro compound into an organic solvent, adding an activated carbon catalyst having a Pd loading capacity of 10 percent, then leading the mixture serving as a material I into a pre-heating module of a microchannel reactor; and 2, respectively pumping preheated material I and a material II hydrogen into a reaction module of the microchannel reactor into a reactor, collecting outflowing reaction liquid, and treating to obtain the lenalidomide. The method is environment-friendly, and has the advantages of high reaction yield, high purity and good economical efficiency.

The invention discloses a method for preparing nitrourea by utilizing a microchannel reactor and belongs to the technical field of organic synthesis application. In the microchannel reactor with a special internal structure, urea, concentrated sulphuric acid and concentrated nitric acid serve as raw materials, and nitrourea is synthesized in reaction time of tens of seconds to several minutes through the novel method. The materials enter the microchannel reactor through a metering pump and then undergo preheating, mixing, reaction and aftertreatment to obtain the nitrourea product. The method has the advantages that the microchannel reactor has excellent heat and mass transport effects and is simple and safe to operate, the product yield is high, and the emission of waste acid is greatly reduced.

The invention belongs to the technical field of environmental protection, and provides a method for enhanced capture of acid gas by cooperation of supergravity and nanofluid technology in order to overcome defects of low gas-liquid mass transfer efficiency and low absorption efficiency of a traditional gas absorption technology. The method comprises steps as follows: nanofluid is prepared from nano amine functionalized mesoporous-structure particles, a surfactant and an absorbent solution, an acid-containing gas mixture enters from a gas inlet, the nanofluid enters from a liquid inlet througha centrifugal pump, the acid-containing gas mixture and the nanofluid are in countercurrent contact in a supergravity rotating packed bed to remove acid gas, and purified gas and the nanofluid are discharged from a gas phase outlet and a liquid phase outlet respectively; the absorptive amount of the acid gas by an absorbent is increased, the use quantity of a solvent is reduced, and the removing time is shortened; a high viscosity liquid and a solid particle contained system can be treated. The device is simple and efficient, occupies a small area, meets the environmental requirement, and canbe applied to the fields of acid gas capture of a thermal power plant, acid gas removal of the chemical industry, acid gas separation from natural gas and the like.

The invention relates to grid packing and a packing structure. The grid packing comprises a plurality of grid plates which are arranged in parallel; each grid plate is provided with more than two through holes; a pipe spacer is arranged between every two grid plates; pull rods in a number corresponding to the number of the through holes alternately penetrate through the grid plates and the pipe spacers; both ends of each pull rod are provided with fastening pieces so that the grid plates and the pipe spacers are connected into a whole; each pull rod is a screw with threads at both ends; and each fastening piece is a nut which is in threaded connection with the screw. The packing structure applied to a packing tower comprises a plurality of layers of grid packing which is arranged vertically; the grid plates of the grid packing are perpendicular to the cross section of the packing tower, and two vertical adjacent layers of the grid packing are staggered and arranged at 45 degrees. The grid plates of the grid packing have small thickness, smooth surfaces, stable integrity, large specific surface area in use, strong anti-clogging capability, little resistance and long service life, thereby being practical, high-efficiency and energy-saving packing.

The invention relates to a method for hydro-upgrading coal tar containing heavy distillate. The method comprises the following steps: adding visbreaking hydrocarbon which mainly comprises hydrocarbons with a boiling range of between 250 and 550 DEG C into a preposed catalyst bed which is filled with hydrogenation demetallization agent, wherein the visbreaking hydrocarbon can be hydrocarbons obtained through separating effluent of a coal tar hydrogenation upgrading reaction. The coal tar raw material and other hot feeds of the preposed catalyst bed are directly mixed and enter the preposed catalyst bed so as to reduce high temperature section time before contacting the catalyst. The method can reduce pressure drop of the preposed catalyst bed, slow down coking, prolong operation period, and is particularly applicable to hydro-upgrading of coal tar containing high-viscosity heavy distillate.

The present invention provides an amplification-effect-free continuous flow synthesis process of tert-butyl peroxy-2-ethylhexyl carbonate. According to the synthesis process, tert-butyl hydroperoxide,an alkali liquid and 2-ethylhexyl chloroformate are used as raw materials and are continuously and sequentially subjected to an alkalization reaction, an esterification reaction and a quenching stepto obtain the tert-butyl peroxy-2-ethylhexyl carbonate; and the synthesis process is performed in an integrated continuous flow reactor, the reaction raw materials such as the tert-butyl hydroperoxide, the alkali liquid and the 2-ethylhexyl chloroformate are continuously added into the material inlet of the integrated continuous flow reactor, and the tert-butyl peroxy-2-ethylhexyl carbonate is continuously obtained from the material outlet of the integrated continuous flow reactor, wherein the amplification effect does not exist, and the total reaction time is less than or equal to 180 s. Compared with the traditional production process, the synthesis process of the present invention has advantages of substantially improved temperature, substantially shortened total reaction time, no amplification effect, stable product index and good reproducibility.

The invention discloses a phosgene adsorbing tower which consists of a tower foundation, a tower body, a feeding hole and a gas phase inlet. The top inside the tower body is provided with an adsorbent distributing groove communicated with the feeding hole, an upper filling layer is arranged above the adsorbent distributing groove, liquid collectors, liquid distributors and filling layers are arranged at intervals below the upper filling layer, and the numbers of the liquid collectors, the liquid distributors and the filling layers are same. The invention has the characteristics of simple structure, easy disassembly and assembly, low cost, small pressure reduction inside the tower, adaptability to high gas phase load, high mass transfer efficiency, higher absorbing efficiency than a floating distillation tower, remarkably-improved phosgene treating ability, good phosgene absorbing effect and stable working.

The invention discloses a clean technique for producing acrylate-hydroxy ester by adopting a continuous process. The clean technique for producing acrylate-hydroxy ester by adopting the continuous process comprises the following steps: 1) dissolving a catalyst and a polymerization inhibitor in acrylic acid, mixing and measuring, and then continuously pumping the obtained mixture into a tubular reactor with ethylene oxide at a certain ratio, wherein the mole ratio of acrylic acid to ethylene oxide is 1:(1.1-1.5); and 2) after reaction is finished, recycling ethylene oxide through low boiling fraction removal, and causing the rest reaction product to continuously enter an evaporator, so that the finished product is obtained. The clean technique for producing the acrylate-hydroxy ester by adopting the continuous process has the beneficial effects that ethylene oxide is excessive, so that the reaction time is short, and less byproducts are produced; reaction polymerization and reaction exotherm controllability is improved, and the production safety is greatly improved; the reaction time is short, the usage amount of the polymerization inhibitor is reduced, colour number can be effectively reduced, and the production cost is reduced; no steam is consumed in a continuous reaction process, and the production energy consumption is reduced; no replacement is required to be carried out after reaction is normally carried out, basically no nitrogen is consumed during production, and the amount of waste gas discharged out is reduced; and ethylene oxide in a degassing process during normal production can be recycled and is not discharged out, so that no pollution is produced to the air and water.

The invention discloses a continuous flow preparation method of diethyl methyl phosphite, which comprises the following steps: continuously adding ethanol and methyl phosphorus dichloride solution into a feed port of a continuous flow reactor, and continuously obtaining diethyl methyl phosphite at a discharge port of the continuous flow reactor. The method has the advantages of small liquid holdup, safe and efficient production process, solving of the problems of long reaction time and low efficiency in a kettle type reaction, high product yield and purity, and simple and efficient process operation.

The invention disclose a TDA dehydrating tower, which comprises a tower body, a circumfluence supply pipe, a recycle gas phase inlet and a TDA feeding hole. An upper distributing groove communicated with the circumfluence supply pipe is formed at the top in the tower body, an upper packing layer is arranged below the upper distributing groove, a liquid catch plate is arranged at the lower part of the upper packing layer, a liquid receiving tank is fixed at the lower part of the liquid catch plate, a liquid downtake communicated thereof is arranged at the bottom of the liquid receiving tank, the liquid downtake is communicated with a lower distributing groove formed at the lower part of the liquid downtake, and a lower packing layer is arranged at the lower part of the lower distributing groove. The TDA dehydrating tower has the advantages of simple structure, easy disassembly and assembly, low cost, high degree of the heat change and quality change of two phases of gas and liquid, good separating effect and high efficiency.

The invention relates to a serrate double-layer wire mesh corrugated packing which forms a serrate corrugated packing sheet structure by mechanically rolling double-layer wire mesh materials, wherein the top end of the wave crest and the top end of the wave trough of a corrugated packing sheet are respectively formed by connecting smooth arc surfaces, and an arc serrate corrugated structure with a smooth tooth top is formed, and a formed corrugated ridge and the axial direction of the packing form an included angle. Compared with the prior art, the serrate double-layer wire mesh corrugated packing is easy to manufacture, excellent in fluid mechanics and mass transfer performance, especially applicable to separating of small-coefficient mixtures which are difficult to separate, such as separation preparing of isotopes, and capable of being popularized and used in the precise separation field of traditional purification of flavors, fragrances and medical intermediates.

The invention provides a continuous production method for a vulcanization accelerator DPG. The method comprises the following steps that (1) diphenylthiourea, a catalyst, ammonium hydroxide and an organic solvent are mixed to obtain a reaction raw material mixture; (2) the reaction raw material mixture and an oxidizing agent are subjected to an oxidation reaction in a continuous flow reactor to obtain a reaction product; (3) the reaction product is post-treated to obtain the vulcanization accelerator DPG, wherein the organic solvent in step (1) can dissolve the diphenylthiourea and the vulcanization accelerator DPG. The method reduces the pressure in the reaction process, improves the utilization rate of the raw materials, stabilizes the product quality, greatly shortens the reaction timecompared with a conventional technology, improves the reaction yield, and effectively overcomes the disadvantage of traditional kettle type batch production.

The invention discloses a method for preparing 2, 4-dinitrochlorobenzene by one-step adiabatic continuous nitration of chlorobenzene, which comprises the following steps: adding a mixed acid solution and an organic phase solution into a microreactor for adiabatic nitration reaction to obtain 2, 4-dinitrochlorobenzene, wherein the mixed acid solution is a mixture of concentrated sulfuric acid and concentrated nitric acid. The organic phase solution is a mixture of chlorobenzene and a heat carrier, and the heat carrier is 2, 4-dinitrochlorobenzene; and a micro-sieve pore structure is arranged in the micro-reactor. The method provided by the invention has the advantages of greenness, energy conservation and high efficiency.

The invention relates to the field of organic synthesis, in particular to a method for continuously synthesizing hydroquinone dihydroxyethyl ether by a micro-channel reactor. Hydroquinone and ethylene oxide are used as raw materials, a catalyst is added into a hydroquinone diluent, the two raw materials are controlled by a metering advection pump to be synchronously input into a micro-channel reaction system, the volume flow of hydroquinone and ethylene oxide is regulated and controlled, reaction liquid reacts in a reaction unit of a micro-channel, and hydroquinone dihydroxyethyl ether is obtained. According to the method, the hydroquinone dihydroxyethyl ether is synthesized by adopting a micro-channel continuous process, so that rapid heating can be realized, the liquid holdup is small, the safety is high, and the flammable and combustible risk of ethylene oxide with relatively high initial concentration in the rapid heating process in an intermittent process can be avoided.