61 results about "Hormone regulation" patented technology

A method and apparatus for delivering corrective therapy through hormone regulation is provided. Inhibition of sympathetic fibers by spinal cord stimulation is used to regulate the levels of hormones such as catecholamines, renin, and calcitonin gene-related peptide. The invention utilizes a closed or open loop feedback system in which physiological parameters such as the concentrations of hormones and sympathetic indicators such as heart rate and urine production are monitored and used to determine the appropriate level of neurostimulation. The site of electrical stimulation includes, but is not limited to, the spinal cord at levels T7–L2 and the associated neural fibers within a region of the T7–L2 dermatomes

A method and apparatus for delivering corrective therapy through hormone regulation is provided. Inhibition of sympathetic fibers by spinal cord stimulation is used to regulate the levels of hormones such as catecholamines, renin, and calcitonin gene-related peptide. The invention utilizes a closed or open loop feedback system in which physiological parameters such as the concentrations of hormones and sympathetic indicators such as heart rate and urine production are monitored and used to determine the appropriate level of neurostimulation. The site of electrical stimulation includes, but is not limited to, the spinal cord at levels T7-L2 and the associated neural fibers within a region of the T7-L2 dermatomes

The invention relates to a tissue culture and rapid propagation method of acer palmatum. The method comprises the following steps of: after a series of sterilization processes, carrying out isolated culture on acer palmatum stems by adopting NN69 as a basic culture medium; and establishing a rapid propagation system of the acer palmatum by utilizing hormone regulation and control to successfully culture an integrated rooting regeneration plant with a transplant survival rate of about 90 percent, wherein a starting culture medium for inoculating a primary generation comprises the NN69, 0.1mg / L of NAA (Naphthylacetic Acid), 0.3mg / L of TDZ (Thidiazuron) and 30g / L of sucrose with a pH value of 5.8; an enrichment culture medium comprises the NN69, 30g / L of sucrose, 0.1mg / L of NAA and 0.8mg / L of KT-30; and a rooting culture medium comprises 1 / 2 NN69, 0.2mg / L of NAA, 20g / L of sucrose and 0.2g / L of active carbon. The method overcomes the defects of long conventional seedling culturing period of the acer palmatum, low cuttage propagation coefficient, and the like and realizes the industrial production of acer palmatum nursery stocks.

The invention discloses a particle swarm optimization manufacturing system double-target production scheduling method based on a bionic strategy, and the method comprises the steps: firstly building amixed flow shop scheduling mathematic model, and determining a scheduling process constraint condition and a target function needing to be solved; proposing particle encoding and decoding based on matrix expression; proposing a speed updating rule based on a hormone regulation mechanism; and proposing a particle swarm optimization algorithm based on a bionic strategy, solving the workshop scheduling model and obtaining a scheduling scheme. The invention provides a particle swarm optimization manufacturing system double-target production scheduling method based on a bionic strategy. Accordingto the system, resource arrangement, capacity balance, quality management, cost and delivery time of enterprises can be controlled, problems on a production line are analyzed and explored, correct technology and management decisions are made for informatization, standardization and automatic construction of the enterprises, and therefore the operation efficiency of the manufacturing enterprises isimproved, and benefits are obtained to the maximum extent.

Disclosed is the use of a klotho protein or related compounds for the diagnosis and treatment of cancer, alone or together with other active pharmaceutical ingredients such as chemotherapeutic agents or hormone-regulating agents.

The invention discloses a flooded gum clone WLEG-17 tissue culture medium which consists of the following components by concentration: 1900-2375mg / L of KNO3, 273-411mg / L of NH4NO3, 270-338mg / L of KH2PO4, 480-540mg / L of MgSO4.7H2O, 300mg / L of Ca(NO3)2.4H2O, 6mg / L of VB2, 0.5mg / L of 6-BA, 0.2mg / L NAA and 4700mg / L of agar; the species and concentration of microelement, ferric salt and organic mattersas well as the concentration of cane sugar are the same as that of an MS culture medium; on the basis of the MS culture medium, the culture medium adjusts the species and concentration of macroelements, adds organic supplementary element VB2, optimizes hormone regulation and agar concentration, and the like, thus providing balanced and reasonable nutritional requirements for the flooded gum cloneWLEG-17 tissue culture seedling, ensuring fast, high efficient and healthy growth thereof, and effectively controlling the generation of healing and vitrifying phenomenon.

Provided are picolinamide and pyrimidine-4-carboxamide compounds, a method for preparing the same, a pharmaceutical composition containing the same, and a medical use using the compound as an agent for preventing, regulating, and treating diseases related to regulation of glucocorticoids by using selective inhibitory activity of the compound for an 11β-HSD1 enzyme. The picolinamide and pyrimidine-4-carboxamide compounds of the present invention are selective inhibitors of human-derived 11β-HSD1 enzymes, and are useful in an agent for preventing, regulating, and treating diseases related to glucocorticoid regulation in which human-derived 11β-HSD1 enzymes are involved, for example, metabolic syndromes such as, type 1 and type 2 diabetes, diabetes later complications, latent autoimmune diabetes adult (LADA), insulin tolerance syndromes, obesity, impaired glucose tolerance (IGT), impaired fasting glucose (IFG), damaged glucose tolerance, dyslipidemia, atherosclerosis, hypertension, etc.

The invention relates to a data driven intelligent controller with an embedded hormone regulation mechanism and a method thereof, output data of an object controlled by the controller is compared with given data inputted as reference for the controlled object through a feedback sensor group, output error of the controlled object is obtained, and the error is simultaneously inputted into a conventional controller and an error threshold evaluation unit. A data driven computing unit is used for running the data according to system history recorded in a historical data storage unit, the current working state between the conventional optimization state and the collaborative optimization state is selected for determining the controller which needs to be optimized, optimization adjustment is carried out on parameters of the controller, the original control quantity obtained by computation is processed by the error threshold evaluation unit and selectively added into the control quantity increment of a hormone regulation unit, and the output of the controller is finally synthesized and sent to the controlled object for implementing the control. The system and the method can improve sensitivity and accuracy of data driven control, and be conductive to keeping the controlled object in the sustained and stable working state.

The invention discloses a culture medium for subculture multiplication of tissue cultured seedlings of red-flesh kiwifruits. On the basis of MS culture medium, through adjusting the types and concentrations of major elements and optimizing the concentration of hormone regulation agar and the like, balanced and reasonable nutritional requirement is provided to the subculture multiplication of the tissue cultured seedlings of the red-flesh kiwifruits, the rapid, efficient and strong growth of the red-flesh kiwifruits is ensured, the inter-node growth is effectively promoted and the multiplication coefficient is improved.

A method of birth control and hormone regulation comprises utilizing a vaginal ring worn continuously during each menstrual cycle. A vaginal ring delivers predetermined doses of progesterone and beta-estradiol. Beta-estradiol does not cause an increase in sex hormone binding globulin and thereby does not decrease a woman's levels of free testosterone and libido.

The present invention is one kind of tissue culture and fast propagation technology for fragrant shaddock. By means of material screening, culture medium component improvement, hormone regulation andother technological means, tissue culture rate of 1000 to 10000 times each year is reached. The present invention makes it possible to provide large amount of fragrant shaddock seedlings in high quality in greening city.

The invention relates to a flowering phase regulation method for camellia flowers. The method comprises hormone regulation, temperature and humidity management, nutrient and water management, illumination management and the like. Accordingly, the natural laws of growth and development and blooming of the camellia flowers can be broken through, the flowering phase of the camellia flowers is effectively regulated, and meanwhile effective nutrient and water management and hormone regulation are effectively conducted on the camellia flowers; on the basis that the flowering phase of the camellia flowers is ensured to be consistent, the flowering phase is effectively controlled, blooming in counter-season of the camellia flowers is achieved, growth and cultivation of the camellia flowers adapt to market requirements, and the benefit of camellia flower growers is greatly increased.

The invention provides an elaeagnus mollis diels oil-lepidium meyenii walp compound tablet and a preparation method thereof; with utilization of a modern nutrition essence extraction process, the health care effects of elaeagnus mollis diels and lepidium meyenii walp are fully played, and synergistic effect of the elaeagnus mollis diels and the lepidium meyenii walp is achieved. In the preparation process, a supercritical carbon dioxide method is adopted for extracting extracts of the elaeagnus mollis diels oil and the lepidium meyenii walp, microcrystalline cellulose, functional oligosaccharide and magnesium stearate are selected as auxiliary materials, sieving and tabletting are carried out to prepare the elaeagnus mollis diels oil-lepidium meyenii walp compound tablet. Rich proteins in the elaeagnus mollis diels seed kernels make up the shortcoming of less lepidium meyenii walp protein content, and lepidium meyenii walp specific active components of macamides and macaenes make up the deficiency of elaeagnus mollis diels in hormone regulation. The elaeagnus mollis diels oil-lepidium meyenii walp compound tablet aims at regulating the human body nutritional balance, besides, can play roles in improving human body immunity, eliminating fatigue, regulating blood lipid and improving sexual functions, and is especially for sub-healthy people.

The invention relates to an endocrine-algorithm-based intelligent plasma density control method for tokomaks. The method includes: using a high-speed data acquisition channel to acquire density information, applying hormone regulation algorithm of endocrine system to the parameter control for a PID (proportion integration differentiation) controller and the ultrashort feedback control, and using a pulse inflating mechanism to inflate a plasma chamber. The hormone regulation algorithm of endocrine system is applied to adjusting three control parameters, namely proportional gain, integration time and derivative time, of the PID controller, and accordingly controlling is higher in timeliness and robustness. The ultrashort feedback control is achieved by the ultrashort feedback mechanism of the neural endocrine system according to the change rate of PID control signals, so that control deviation is reduced to zero faster and system rapidity and stability are further increased. The endocrine-algorithm-based intelligent plasma density control method for tokomaks allows for real-time and stable control of plasma density for tokomak nuclear fusion devices, and is intelligent.

The invention provides a Tripterygium hypoglaucum seed propagation method. The method includes the steps of low-temperature storage of seeds, vernalization of the seeds, seed sowing, intertillage management, etc. The step of vernalization of the seeds is as follows: storing the Tripterygium hypoglaucum seeds that have been stored at a low temperature in sand at room temperature in a moisturizing and ventilating condition for one month; and after soaking of the Tripterygium hypoglaucum seeds stored in sand in gibberellin, placing the seeds in a condition with temperature ranging from 7+ / -2 DEG C, and maintaining illumination and humidity for one month. Through exploring and researching, a low-temperature treatment method and a hormone regulation method are adopted to overcome a factor of instability of a seed germination rate. Therefore, the seed germination rate is increased. Moreover, a systematic method is employed to lay a foundation for artificial cultivation in future.

The invention discloses a compound plant-caused transdermal patch for treating prostatic hyperplasia and a preparation method thereof. The transdermal patch comprises the main components of, by weight, 20 parts of African pygeum extract, 20 parts of serenoa serrulata extract, 12 parts of pumpkin seed oil, 11 parts of tribulus terrestris extract, 12 parts of eurycoma longifolia extract, 12 parts of boschniakia rossica extract, 12 parts of cherokee rose fruit extract and 1 part of polyvinylpyrrolidone. A preparation method includes the concrete steps of dosing, coating, covering and punching. In combination with the effects that the kidneys are invigorated, Yang is strengthened, qi is benefited, blood circulation is promoted, essence is secured, urination is reduced, and sterilization, inflammation prevention, swelling elimination, hormone regulation and tissue proliferation restraining are carried out, the transdermal patch comprehensively improves internal and external physiological states of the prostate at the physiological level of molecules, eliminates inflammation and proliferation, and recovers the prostate body; direct transdermal patching on the focus is adopted, the internal illness is treated by external treatment, in this way, medicine penetration and medicine absorption are effectively achieved for the prostate, and the pathological conditions of the prostate are directly improved for a patient.

The invention discloses an anti-breeding rodenticide. Melia azedarach oil is served as an anti-breeding agent, and the weight percent of the melia azedarach oil in the anti-breeding rodenticide accouts for 0.08%-0.1%. Through researching the intrinsic rules and hormone regulation mechanism of mouse breeding as well as studying the toxicological and function mechanism of a vegetable anti-breeding agent, ideal anti-breeding agent-melia azedarach oil is screened. The anti-breeding rodenticide is low in effective dosage, makes mice infertile, and has the advantages of low toxicity index, high safety, no harm to human being and animals and no secondary poisoning. After the anti-breeding rodenticide is eaten 10 days later, main reproductive organs-testicles of male mice generate the following variation: the organ coefficient gets small, the sperm amount is reduced, the seminiferous tubule diameter is thinned, lumens are reduced, germinal epithelium thickness is thinned, and interstitial cells are decreased; and ovarial organ coefficient of female mice is obviously reduced, and the corpus luteum in an ovarial structure is contracted. Dead fetus are increased after male and female mice coition, and the breeding number is greatly decreased.

The invention provides an HPLC method for measuring the contents of variousendogenous hormones in salvia miltiorrhiza bunge at the same time. The method comprises the following steps: a, preparing a test solution; b, preparing a reference solution; c, respectively injecting the test solution and the reference solution into a high performance liquid chromatograph to detect the solution; d, calculating the contents of various hormones in salvia miltiorrhiza bunge. The method can measure the contents of 6 endogenous hormones in salvia miltiorrhiza bunge at the same time, is accurate, reliable, simple and rapid, provides an effective theoretical basis for the research of mechanism of male sterile, and further lays a good foundation for developing the exogenous hormone regulation and variety optimization of stamen fertility of salvia miltiorrhiza bunge.

The invention relates to the technical field of gene engineering, in particular to application of a KRP gene in pest control. According to the application provided by the invention, through construction of a CRISPR / Cas9 knockout strain of silkworm BmKRP, the influence of a new transcription factor BmKRP on the reproductive process of female silkworms is preliminarily explored and studied; and through observation on the silkworm BmKRP<- / -> phenotype, the effect that the deletion of BmKRP influences the female reproduction of silkworms, resulting in ovarian reduction, oocyte volume reduction andadult egg laying number reduction is found; and the effects that the mutation deletion of BmKRP influences the combination of BmKRP with reaction elements on a BmKrh1 promoter, so that BmKr-h1 does not express or down-regulates the expression, and important significance is realized on explaining a molecular mechanism of the silkworm hormone regulation reproduction are found. Through study, a similar control mechanism existing in other insects is speculated. Clues and theoretical guidance are provided for beneficial insect utilization, and pest control new targets and new strategies, and the application significance is realized.

The invention discloses a composition for improving male erectile dysfunction and relieving fatigue. The composition comprises the following components in parts by weight: 10-65 parts of fruits of aronia melanocarpa, 0.5-10 parts of black raw ginger, 5-50 parts of oyster peptide and / or oats peptide, 5-50 parts of maca, 1-10 parts of fructus lycii extract, 1-10 parts of ginseng extract and 1-10 parts of siberian solomonseal rhizome extract. The composition uses the fruits of aronia melanocarpa containing a large amount of polyphenols and having strong antioxidant activity as main raw materials,and the black raw ginger extract with function for improving blood circulation, arginine-rich oyster peptide, traditional Chinese herbal medicines, such as ginseng, siberian solomonseal rhizome and fructus lycii with anti-oxidation and mild nourishing effects, and the maca with libido enhancement and hormone regulation effects are added as auxiliary raw materials. The composition can achieve an effect of improving male erectile dysfunction and relieving fatigue more safely and effectively.

The invention provides a cultivation method capable of prolonging the flowering and fruiting period of peach trees. By selecting a specific variety and a shed or a greenhouse with strong light transmittance and improving soil, a foundation for high yield is laid, the survival rate is improved through final planting, and high-yield plants can be obtained by performing water and fertilizer management, temperature and humidity regulation, light regulation, hormone regulation and shaping and trimming at different periods; and through organic combination and coordination of the steps, the cultivated peach trees have a strong tree trend, the flowering period is brought forward, the flowering and fruiting period is obviously prolonged, and the yield is increased, so that the economic benefit is improved greatly.

The present disclosure relates to a method for preventing, alleviating, improving or treating female hormone regulation disorder or symptoms, which contains a green tea extract with contents of ingredients changed. Specifically, the method according to an aspect of the present disclosure includes a step of administering an effective amount of a green tea extract, which contains (−)-gallocatechin gallate (GCG) and (−)-epigallocatechin gallate (EGCG) at specific contents, to a subject in need thereof, and may exhibit an effect of preventing, alleviating, improving or treating female hormone regulation disorder or symptoms.

The invention discloses a method for mining industrial cannabis sativa hormone regulation response genes based on a metabonomics technology, and belongs to the technical field of industrial cannabis sativa differential metabolite identification. The method comprises the following steps: soaking seeds with hormone for 3-5 hours by taking distilled water seed soaking as a contrast, and then planting the seeds in a greenhouse; selecting top-end leaves of female plants in the contrast and treatment group in the flowering period, quickly freezing with liquid nitrogen, storing at-80 DEG C, and analyzing metabolome for later use; extracting a metabolite and preparing a sample; performing LC-MS analysis; carrying out data preprocessing and metabolite identification; and completing gene mining through mapping analysis and database query analysis. According to the invention, the influence of exogenous hormone on the different metabolites in the flowering phase of the Chinese hemp flowers is researched, detailed information is provided for deeply excavating metabolites, difference changes and the like which respond to hormone regulation in the flowering phase, and technical reference and theoretical support are provided for researches on regulation and control of growth and development, molecular breeding and the like by using a plant growth regulator in production.

The invention relates to the technical field of microalgae, in particular to application of a steroid hormone and a regulator thereof. The research finds that the physiological metabolism process of the algae can be regulated by exogenously giving the steroid hormone or utilizing the steroid hormone regulator, including regulating or controlling the growth of the algae, the accumulation of secondary metabolites of the algae or the stress resistance of the algae and the like. Experiments show that by exogenously giving the steroid hormone and overexpressing key enzyme genes (such as steroid hormone synthetic genes) for improving the steroid hormone level, the growth of algae can be promoted.

The invention provides a method for reducing fruit drop of figs. The method includes the steps of fertilization management, moisture management, illumination management, hormone regulation, removal ofleaves and other aspects. During the fertilization management, the fertilization amount and frequency are controlled, and luxuriant growth of branches and leaves is restrained in order to reduce competition with fruits for nutrients; during the moisture management, trickle irrigation is combined with plastic film mulching, the utilization efficiency of moisture is improved, the ventilation performance among lines is improved, and stimulation caused by strong light at high temperature within a short time is reduced; during the hormone regulation, auxin is used for protecting flowers and the fruits; during removal of the leaves, consumption of nutrients by useless leaves is reduced, and the shading degree of a field is lowered. By means of the measures above from multiple aspects, the occurrence of fruit drop of the figs can be effectively reduced.

The invention provides a rooting culture medium for sea buckthorn tissue culture. The rooting culture medium is characterized by using a 1 / 2MS culture medium as a basal culture medium into which 230-250mg / L of NH4NO3, 30-35mg / L of MgSO4.7H2O, 15-20mg / L of NaH2PO4.H2O, 2-4mg / L of inositol, 0.1-0.2mg / L of glycine, 0.1mg / L of indole-3-acetic acid, 30g / L of sucrose and 6g / L of agar are added. The invention provides the rooting culture medium for sea buckthorn tissue culture; on the basis of the 1 / 2MS culture medium, through adjustment of the types and the concentrations of major elements, optimization of hormone regulation, optimization of light irradiation and the like, the rooting culture medium with balanced and reasonable nutrients is provided for tissue-cultured sea buckthorn rooting seedlings, so that fast, efficient and robust growth of the sea buckthorn rooting seedlings can be promoted.

The invention provide a 3D printed artificial ovarium biological stent capable of activating an original ovarian follicle. According to the 3D printed artificial ovarium biological stent, a 3D printing technology is utilized to mix an original ovarian follicle activating agent and hormones and growth factors which can promote the developing of the ovarian follicle into a stent material to be molded through printing, an ovarian cortex fragment which contains the original ovarian follicle is transplanted, after the cortex fragment is transplanted back to the body, the cortex fragment can achievebetter stent protection and more diversified nutrient supplying, the biological stent is gradually degraded in the body to sustainably release the ovarian follicle activating agent, and therefore theoriginal ovarian follicle is sustainably activated. The stent has the advantages that the in vitro activating time of the original ovarian follicle is greatly reduced, a novel researching tool is provided for an revealing an original ovarian follicle activating mechanism, the waiting time of the patient is reduced on the basis that secondary surgery is avoided, and a novel choice is provided forthe clinical treatment of premature ovarian failure and an assisted reproduction technology; after the ovarian follicle is activated, a large number of hormones are secreted to regulate the secretionin the body, and a novel researching direction is provided for improving comprehensive symptoms of menopause and ageing slowing.

The invention belongs to the technical field of plant tissue culture rooting media and provides a photinia serrulata tissue culture seedling rooting medium and a culture method. According to the photinia serrulata tissue culture seedling rooting medium, an MS medium serves as a minimal medium, 10-19 g / L saccharose, 1.5-2.55 g / L activated carbon, 1.5-1.7 g / L organic fertilizer components, 1.5-2.6 ml / L sterilization powder and 0.5-1.8 g / L inorganic salt composition are added into the MS medium, wherein the pH value of the rooting medium ranges from 5.4 to 6.1. Based on the MS medium, balanced and reasonable nutritional requirements are provided for photinia serrulata tissue culture rooting seedlings by adjusting the varieties and concentrations of macroelements, optimizing hormone regulation and control and the like, and the seedlings are promoted to grow rapidly, efficiently and strongly.

The invention relates to a cyclic flowering method of potted asiatic hybrids. The method comprises the following steps of (1) physical seedball culture; (2) chemical after-ripening; (3) pot sealing for moisturizing; (4) vigour induction; (5) ex-warehouse flower forcing. The provided post-flowering rejuvenation method is simple and easy to implement, and can make variety degeneration after the potted asiatic hybrids bloom fully restored, through the interactive use of the temperature and hormone regulation, the seedball vigour is induced to be fully released, the potted asiatic hybrids after flowering is promoted to produce high-quality flowers again from the new year to the May day, and cyclic utilization of 'flowering-withering-rejuvenation-flowering-withering-rejuvenation' of the pottedasiatic hybrids is achieved.