The invention discloses an efficient energy-saving reactive printing process, which comprises the following steps: (1) pretreatment: performing body inspection, cloth arrangement, sewing, singeing, desizing, scouring, oxygen bleaching and mercerization on to-be-reactively printed cloth in sequence; (2) size mixing: melting colorants used for reactive printing under the condition of 70 to 90 DEG C, filtering and then adding the molten colorants to raw paste, and evenly stirring; (3) printing: during printing, arranging a printing screen of a dark colorant to be in front of a printing screen of a light colorant; (4) after the printing is finished, ageing, washing and setting to obtain a reactive printed product. According to the efficient energy-saving reactive printing process disclosed by the invention, through a chemical action between the dye colorants and the cloth, the color fading problem of reactive printing can be thoroughly solved, so that the product quality is greatly improved; meanwhile, compared with traditional reactive printing process, the efficient energy-saving reactive printing process has the advantages that processes are saved, the printing cost is reduced, and the production efficiency is increased.