33results about How to "Mild desorption conditions" patented technology

The invention provides a method for extracting refined high-purity tea saponin by taking camellia oleifera seed cake as raw material. The method comprises the following steps: smashing the camellia oleifera seed cake after squeezing and oil extraction; carrying out reflux extraction with 70-95% ethanol; adding chitosan (the volume ratio of the chitosan solution to extraction liquid is 9-13:100) to the extraction liquid for flocculation and purification; eluting and removing impurities from the purified clear liquid with a sodium hydroxide solution after the purified clear liquid is absorbed by AB-8 macropore adsorbent resin; eluting the tea saponin with 60-90% ethanol; decoloring the eluent containing the tea saponin with hydrogen peroxide (the volume ratio of the hydrogen peroxide to theeluent is 3-6:100); and steam drying the decolored solution to obtain milky powdery tea saponin. The invention has the advantages of simple process, no pollution and low production cost, the purity is higher than 95%, and the tea saponin has good color and can be widely applied to the fields of daily chemical industry, textile, medicine, food industry and the like.

The invention discloses a method for separating pentamethylene diamine by utilizing ultrahigh crosslinking resin absorption. The method comprises the following steps: causing a preprocessed pentamethylene diamine fermentation liquor pass by an adsorption column filled with ultrahigh crosslinking resin, absorbing, cleaning impurities and desorbing, thereby acquiring a pentamethylene diamine adipic acid solution. According to the method provided by the invention, the adsorption column is adopted for separating the pentamethylene diamine from the fermentation liquor; all the operations can be performed under room temperature; the energy consumption in the separating process and the dosage of the organic extraction agent are greatly reduced; the selected adsorbing medium has the advantages of high adsorption capacity for pentamethylene diamine, high physical-chemical property stability, high adsorptive selectivity, mild desorbing condition, easiness in regeneration, long service life, and the like; the used adsorption column can be regenerated by using water; the acid-base or organic solvent need not be consumed; the energy consumption can be reduced and the wastewater discharge can be reduced; the problem of environmental pollution is avoided; the method is a more clean and environment-friendly production technique.

The invention discloses a method for extracting acetoin from fermentation liquor. Pretreated acetoin fermentation liquor is conducted to adsorption, impurity washing and elution through an adsorption column in which sorbent is contained, eluant is collected, and then acetoin solution is obtained, wherein the sorbent adopts hyper-crosslinked resin HD-02; the framework of the resin adopts polystyrene; polystyrene is conducted to Friedel-Crafts and then is prepared into the acetoin after cross linking reaction; and the acetoin has medium polarity, with the percent of void being 40 to 50 percent, the particle size being 0.42 to 0.55 mm, the wet density being 1.05 to 2.02g / cm<3>, the average specific surface being 1450 to 1800m<2> / g, the average pore diameter being 1.62 to 2.70 nm, the pore volume being 0.73 to 0.86 cm<3> / g, and the water content being 42 to 45 percent. The method is simple and efficient, the energy consumption is low, and the acetoin is effectively separated from the fermentation liquor.

The invention relates to a preparation method for total flavonoids in V.amoena Fisch.var.angusta Freyn.. According to the technical scheme, V.amoena Fisch.var.angusta Freyn. medicinal material powder is taken and extracted at 70-90 DEG C with a 40-95% ethanol water solution as the solvent in the liquid-material ratio of 1:(10-20), and extraction liquor is obtained; an adsorption column filled with weak polarity-medium polarity macroporous adsorption resin is selected, the total flavonoid loading concentration is 0.21-3.18 mg / mL, the pH is regulated to be 1-8, samples are loaded on the adsorption column, the loading volume is 4-6 times the resin column bed volume, the adsorption flow velocity is regulated to be 2-6 mL / min for dynamic adsorption, elution is carried out with a 30-95% ethanol water solution at the flow velocity of 2-6 mL / min, and elution liquor is collected. According to the macroporous adsorption resin preparation method for total flavonoids, the yield of total flavonoids is high, desorption conditions are mild, the service cycle is long, regeneration is easy and convenient, the extraction ratio is high, and the cost is low; the preparation method is suitable for popularization and application in industrial production.

The invention discloses dealkalized endonuclease magnetic molecular imprinting nano-particles as well as a preparation method and application thereof. The preparation method comprises the following steps: modifying the surface of a silicon dioxide-coated magnetic core used as a carrier by avidin which has strong affinity interaction with APE1 and is used as a functional monomer, forming an imprinting layer by taking the APE1 as a template molecule and taking a polymeric material as a monomer and a crosslinking agent, and finally eluting an APE1 template to form an imprinting cavity, thereby obtaining the magnetic molecular imprinting nano-particles. The magnetic molecular imprinting nano-particles prepared according to the method have advantages of strong affinity interaction with a template protein APE1, high selectivity, high interference resistance and high combination and desorption speeds. The preparation technology is simple in process, controllable in reaction and high in imprinting efficiency. The magnetic molecular imprinting nano-particles disclosed by the invention can selectively recognize, separate and enrich low-abundance APE1 in a complicated biological sample, and has a high industrial production value.

The invention discloses natural perfume refining fluid suitable for cigarette fluid of electronic cigarettes and cigarette fluid and a preparation method thereof, and belongs to the technical field of cigarette fluid of electronic cigarettes. Separation and impurity removal are performed on natural perfume such as extract, tincture and absolute oil through a macroporous adsorption resin column chromatography technology, high-boiling-point components such as monosaccharide and disaccharide and macromolecular components such as protein, polysaccharide and pectin in the natural perfume are simultaneously and effectively removed according to the differences of polarities and molecular sizes of all the components in the mixture, the components unfavorable for the smoking mouthfeel of the electronic cigarettes are removed, and the problem that charring flavor is generated due to the fact that the substances are deposited on heating wires is solved; meanwhile, the solubleness of the natural perfume in propylene glycol and glycerinum is improved, therefore, the cigarette fluid of the electronic cigarettes becomes clear and bright, the emission performance of perfume is significantly improved, the sweet greasy feeling is reduced, and the sensory effect is significantly improved.

The invention discloses a process for recovering and refining potassium chloride in organic chemical wastewater. The process comprises the following specific steps: a potassium chloride aqueous solution enters a standing layering tank, a water layer and an oil layer are separated, the oil layer returns to a production system, the water layer enters a precision filter, effluent water obtained by filtration enters a resin adsorption tower, phenol, chlorobenzene and the like are adsorbed by adsorption resin, effluent water obtained from the resin adsorption tower enters a coagulation sedimentation tank, the pH of the potassium chloride aqueous solution is adjusted to be neutral, the separated supernatant overflows to a supernatant tank, effluent water obtained from the supernatant tank is filtered, the filtered water reaches a metal special resin tower to remove metals, effluent water obtained from the metal resin tower enters a middle water tank, effluent water obtained from the middle water tank is pumped into an MVR evaporation system by using a pump, and finally effluent water obtained from the MVR evaporation system enters a cooling crystallizing tank for cooling crystallization,and a salt obtained by the cooling crystallization is used as the product. Compared with the prior art, the process provided by the invention has the following advantages: organic pollutants and metal ions in the wastewater are efficiently removed by utilizing the resin, the high-quality potassium chloride is recovered, the waste is recycled, the regeneration treatment is convenient, the use period is long, the operation is stable, the operating costs are saved, and the automation degree is high.

The invention discloses a method for separating and purifying pentamethylenediamine. The pretreated pentamethylenediamine conversion solution is passed through an adsorption column equipped with an adsorption resin. After the adsorption is saturated, water is used as a washing agent to wash impurities, and water is used as a desorbing agent. Desorb the pentamethylenediamine solution to obtain an aqueous solution of pentamethylenediamine, and then directly enter the aqueous solution of pentamethylenediamine into a rectification tower for rectification to obtain pure pentamethylenediamine; wherein, the adsorption resin is based on styrene or acrylate body, divinylbenzene is used as a cross-linking agent to obtain a weakly polar adsorption resin; or, a polar adsorption resin obtained by using an aminating agent to modify the weakly polar adsorption resin with amine groups; the resin Stable physical and chemical properties, insoluble in acid, alkali and organic solvents, not affected by inorganic salts and strong ionic low-molecular compounds; the above-mentioned adsorption resin has an average particle size of 0.4-0.8mm and a water content of 41-47wt%. The average pore diameter is 4.6-6.3nm, the porosity is 30%-40%, and the wet density is 1.12g / cm 3 , with an average specific surface area of ​​786‑862m 2 / g, average pore volume 0.97~1.12cm 3 / g.

The invention belongs to the technical field of traditional Chinese medicine, and specifically relates to a Runing granule and a preparation method thereof, which comprises the following components in parts by weight: 200-350 parts of Bupleuri, 100-300 parts of Angelica sinensis, 30-150 parts of Vinegar Cyperus, 30-150 parts of Salvia miltiorrhiza, 50-150 parts of fried white peony root, 50-100 parts of Wang Buliuxing, 50-100 parts of red peony root, 50-150 parts of fried Atractylodes macrocephala, 20-150 parts of Poria cocos, 30-80 parts of green peel, tangerine peel 20 to 100 parts and 20 to 50 parts of mint. The Runing granule prepared by the invention regulates qi and relieves stagnation, and is used for breast addiction caused by liver qi stagnation.

The invention relates to a terpolymer hydrogel capable of enriching and separating uranium in aqueous solution and a preparation method thereof. The terpolymer hydrogel takes K2S2O8-NaHSO3 as an initiator, takes acrylonitrile, acrylic acid and beta-cyclodextrin as raw materials, an emulsion polymerisation method is used for preparing a product through a binary grafting copolymerization reaction of acrylonitrile and beta-cyclodextrin, and the functional terpolymer hydrogel acrylonitrile-acrylic acid-beta-cyclodextrin (AN / AA / beta-CD) can be synthesized. The terpolymer hydrogel has the advantages that the raw materials are easily available, the terpolymer hydrogel is a uranium separating agent with good performance, adsorption rate is high, the preparation method is simple and easy to carry out, desorption condition is mild, no massive strong acid as well as poisonous and harmful substances can be discharged during a whole process, no secondary pollutant is generated, and the novel functional terpolymer hydrogel is environmentally friendly, and can be recycled.

The invention discloses a preparation method for extracting anticancer valid-position medicine SHIKEMOXIN from sweetsop, comprising the steps of crushing sweetsop seeds, putting the crushed sweetsop seeds in an ethanol solution with the volume that is 3-5 times of that of the sweetsop seeds, leaching for 1 hour in a slight boiling manner in the ethanol solution, carrying out reduced pressure distillation for leaching liquor to recycle ethanol; extracting the medicine dreg for two times by the same method, merging and separating sweetsop total lactones liquid medicine, separating and eluting the sweetsop total lactones liquid medicine by a macroporous resin column, guiding and merging the desired fraction by thin layer chromatography or high efficiency liquid chromatography, recycling solvents, and drying under reduced pressure to obtain the sweetsop lactones anti-cancer valid-position medicine, namely SHIKEMOXIN. The method not only solves the problem that the toxic organic solvent used in the production harms health of operators, but also the production technology is more suitable for industrial production on a large scale, and the method has strong practicality and promotional value.

The invention relates to a traditional Chinese medicine for relieving cough and reducing phlegm and a preparation method thereof. Hua, Baibu, Scrophulariaceae, Ophiopogon japonicus, Budisma, Asparagus, Schisandra, Citrus aurantium, Melon wilt, pinellia, woody fragrance, aristolochia, mulberry leaves, and poppy shells are configured according to a certain weight to achieve optimization The purpose of immersing, extracting, decocting, concentrating, filtering and other steps to obtain cough-relieving and phlegm-reducing granules; the raw materials of the traditional Chinese medicine of the present invention cooperate with each other to dry dampness and resolve phlegm, evacuate wind-heat, promote body fluid, relieve cough and asthma, and moisten the intestines The function of laxative is mainly used for cough with excess phlegm, asthma, sore throat, lung heat and phlegm stagnation, yellow and sticky phlegm, etc. It absorbs well, is not easy to produce drug resistance, and has no toxic side effects.

The invention discloses a method for adsorptive separation of aromatic aldehyde in lignin oxidized liquid.Lignocellulose rich in lignin is adopted as a raw material, and after a wet process catalytic oxidation reaction, the lignin oxidized liquid is prepared; the pH value of the lignin oxidized liquid is adjusted to be slightly acidic, and attapulgite is adopted for adsorptive separation of the aromatic aldehyde compound in the lignin oxidized liquid; finally eluent is used for eluting the aromatic aldehyde compound adsorbed on the attapulgite away, and preliminary separation of the aromatic aldehyde compound from a lignin catalytic oxidation degradation product is achieved.Adsorption is achieved through the attapulgite, p-hydroxy benzaldehyde, vanillic aldehyde and syringaldehyde with commercial value are preliminarily separated from the lignin catalytic oxidation degradation product, and the separation and extraction process of the lignin degradation product is simplified.

The invention relates to a traditional Chinese medicine for treating colds and a preparation method thereof. In the method, antelope horns, burdock seeds, nepeta, bellflower, licorice, honeysuckle, light bamboo leaves, light tempeh, menthol, and forsythia are configured in certain parts by weight. Decoct the above-mentioned antelope horns to obtain the extract, steam distill nepeta and forsythia to obtain the distillate, add honeysuckle, light bamboo leaves, light tempeh, burdock seeds, licorice, bellflower and water to the residue of nepeta and forsythia, decoct, and let stand , filter the supernatant, concentrate to obtain a clear paste, dissolve menthol with ethanol, combine with the extract, distillate, and clear paste obtained above, add simple syrup, preservatives, add water to adjust, filter, pot, and sterilize , to obtain; the present invention has the effects of heat-clearing and toxic substances removing, eliminating phlegm and relieving cough, moisturizing the lungs and lowering qi, and has significant curative effects on symptoms such as fever, cough, and sore throat caused by colds, and has low cost and no side effects, and is worthy of wide promotion.

The invention discloses a new medicinal application of irisinin, which can be prepared into any conventional medicament according to the conventional pharmaceutical technology, and is used for preparing anti-atherosclerotic drugs. The invention also discloses a new process for preparing irisin, which uses ethanol and macroporous resin to separate irisin monomer from Pueraria japonica, does not use toxic organic solvents, does not pollute the environment, and meets the requirement of environmental protection. Ethanol and macroporous resin can be reused, which reduces the cost of drugs. Compared with silica gel columns, it has more sample loading, less time-consuming and high efficiency, and is suitable for industrial production.

The invention discloses a method for enriching rhenium from copper smelting waste acid. According to the adopted technical schemes, precipitant is added into the copper smelting waste acid containing low-concentration rhenium until pH of a solution is 8-12, filter pressing and separating are conducted, filtrate is collected, the pH is adjusted to 1-8, the filtrate is pretreated through a biological carbon adsorption tower, interfering ions are further removed, then the rhenium in the solution is absorbed through a copper-carrying biological carbon adsorption tower, adsorption is stopped after adsorption reaches saturation, elution with an alkaline liquid and concentration are conducted, and rhenium-containing enrichment liquid is obtained. According to the method for enriching the rhenium from the copper smelting waste acid, technology is reasonable, no-pollution is achieved, the operation condition is mild, the recovery rate is up to over 99%, the maximum adsorption capacity is that 100 mg rhenium can be absorbed by per gram of adsorbent, rhenium enrichment is increased by more than 100 times, and rapid and efficient recovery of the low-concentration rhenium in the copper smelting waste acid can be realized.

The invention belongs to the technical field of traditional Chinese medicine, and specifically relates to a Paishi granule, a preparation method thereof, and a new application of medicine, which include the following components in parts by weight: 200-300 parts of Lisiana, 30-80 parts of Plantago, 30-80 parts of Tong, 40-70 parts of Xu Changqing, 30-70 parts of Shiwei, 160-200 parts of Lonicerae vine, 160-250 parts of talc, 20-70 parts of Qumai, 30-80 parts of fennel seed and 60-100 parts of licorice , Paishi granule of the present invention can be used for treating chronic cholecystitis. The invention's Lisiana is beneficial to the dissolution and discharge of kidney stones and urolithiasis, and then it is combined with Plantago Seed, Akebia, Xu Changqing, Shiwei, Honeysuckle, Talc, Cornucopia, Fennel Seed and Licorice. Calculus treatment effect is remarkable, at the same time, it has the effect of treating chronic cholecystitis.

The invention relates to a preparation method of total flavonoids in Sayama vetch. The technical scheme adopted is: take the medicinal material powder of the wild pea from the mountain, use 40-95% ethanol aqueous solution as a solvent, and extract at a liquid-to-material ratio of 1:10-20 at 70-90° C. to obtain an extract. Select an adsorption column filled with weakly polar-medium polar macroporous adsorption resin, the concentration of total flavonoids in the sample is 0.21-3.18mg / mL, adjust the pH to 1-8, and load the sample on the adsorption column with a sample volume of 4- 6 times the volume of the resin column bed, adjust the adsorption flow rate to 2-6mL / min for dynamic adsorption, use 30-95% ethanol aqueous solution, 2-6mL / min flow rate for elution, and collect the eluate. The preparation method of the total flavone macroporous adsorption resin of the present invention has high yield of total flavonoids, relatively mild desorption conditions, long service life, simple regeneration, high extraction rate and low cost, and is suitable for popularization and application of industrial production.

The invention discloses a method for adsorbing and separating xanthophyll by utilizing hyper-cross-linked resin. The method comprises the following steps of adsorbing and desorbing a preprocessed xanthophyll saponification solution by an adsorption column which is filled with the hyper-cross-linked resin, and obtaining a xanthophyll solution, wherein the hyper-cross-linked resin is prepared through a Friedel-Crafts cross-linking reaction and an acetic anhydride reaction by taking polystyrene-divinyl benzene as a skeleton, the average grain diameter of the hyper-cross-linked resin is 0.3mm to 0.8mm, the water content is 20 weight percent to 50 weight percent, the pore diameter is 1.5nm to 5.5nm, the porosity is 25 percent to 45 percent, the wet density is 1.05g / cm<3> to 1.18g / cm<3>, the average specific surface area is 500m<2> / g to 950m<2> / g, the average pore volume is 0.542cm<3> / g to 0.985cm<3> / g, and the functional group is the carbonyl group. An adsorption medium adopted by the method disclosed by the invention has the advantages of large xanthophyll adsorption capacity, good adsorption selectivity, gentle desorption conditions, easiness in regeneration, long service cycle and the like.

The invention discloses a gulonic acid adsorption separation method utilizing hyper-crosslinked resin. According to the gulonic acid adsorption separation method utilizing the hyper-crosslinked resin, a preprocessed gulonic acid fermentation broth is subjected to the processes of absorption, impurity washing and desorption through an adsorbing column filled with the hyper-crosslinked resin, and finally a gulonic acid solution is obtained. The hyper-crosslinked resin is prepared through a Friedel-Crafts cross-linking reaction and with polystyrene-divinyl benzene as a framework, and is weak in polarity and good in hydrophilia; the average grain diameter is 0.42-0.56mm, the water content is 43wt%, the bore diameter is 1.92nm, the porosity is 30-40%, the wet density 1.09g / cm3, the average specific surface area is 1645.5m2 / g, the average pore volume is 0.732cm3 / g, and a functional group is a carbanyl group. The adsorption medium adopted by the method has the advantages of being large in adsorption capacity for the gulonic acid, good in adsorptive selectivity, mild in desorption condition and long in service cycle, enabling regeneration to be easy and the like.