39results about How to "Precise control of reaction time" patented technology

The invention relates to a method for preparing alpha-sulfonic fatty acid ester by sulfonating fatty acid ester, comprising the following steps: injecting the fatty acid ester and a sulfonating agent into a micro-structural reactor (5) and a reactor (6) inside diameter of which is a micro passage respectively, mixing and sulfonating the fatty acid ester and the sulfonating agent, controlling the reaction temperature between 50 and 100 DEG C, and controlling the reaction materials to stay for 1ms to 1s in the micro-structural reactor (5) and stay for 0.5 to 30 minutes in the micro-passage reactor (6); and then injecting the reaction materials into a micro-passage reactor (7), aging the reaction materials at a reaction temperature between 50 and 100 DEG C, and controlling the reaction materials to stay for 0.5 to 30 minutes in the micro-passage reactor to obtain the alpha-sulfonic fatty acid ester. In the method, the novel micro-structural reactor is adopted, the defect of difficult control due to strong reaction heat release in the prior art is overcome, the materials can be mixed evenly, the released reaction heat can be removed in time, the reaction time can be controlled accurately, and the method has the advantages of good sulfonating efficiency, simple and safe operation and good product quality.

The invention discloses a method for synthesizing 3,4-dinitropyrazole by using a micro-channel reactor. The method comprises the following steps: with pyrazole as a raw material, subjecting pyrazole and a nitric-acetic anhydride system to nitration in the micro-channel reactor so as to synthesize N-nitropyrazole; then with N-nitropyrazole as a raw material, carrying out thermal rearrangement so asto synthesize 3-nitropyrazole; and finally, with 3-nitropyrazole as a raw material, synthesizing 3,4-dinitropyrazole in virtue of a nitric acid-sulfur acid mixed acid system in the micro-channel reactor. According to the invention, the micro-channel reactor is employed, so the adverse outcomes of hardly controllable process, proneness to local overheating which leads to dangers, easy generation of side reactions and the like of convetional tank reactors are avoided, rapid reaction is realized, and direct enlargement can be realized through increase of the number of parallel micro-channel reactors. With the method, the yield of the synthesized 3,4-dinitropyrazole reaches 87.5%, and the purity of the synthesized 3,4-dinitropyrazole reaches 99.8%.

The invention discloses a preparation method of a rapidly-thinned single-element tellurene two-dimensional material, the preparation method mainly comprises the following steps: (1) transferring a pre-prepared single-element tellurene material precipitate into deionized water, and standing for later use; (2) continuously introducing oxygen into the deionized water dispersed with the single-element tellurene material precipitate in the step (1), and heating the deionized water to obtain a single-element tellurene material dispersion liquid; and (3) dispensing the single-element tellurene material dispersion liquid obtained in the step (2) onto a target substrate by adopting a dispensing method to obtain the thin-layer single-element tellurene two-dimensional material. According to the thinning method, the thickness of the single-element tellurene two-dimensional material can be accurately controlled by controlling the flow rate of introduced oxygen and the reaction time, other polar organic solvents do not need to be adopted, new impurity molecules cannot be introduced, and the preparation process is easy to operate, high in controllability, green, environmentally friendly and suitable for industrial production, and a rapid and controllable method is provided for the preparation of the thin-layer single-element tellurene two-dimensional material.

The invention discloses a methyl mercury visual detection method of gold-mercury alloy nanoparticle growth regulation and control based on a DNA template, and belongs to the technical field of heavy metal detection. According to the method, an HT9 DNA nucleic acid template is uniformly mixed with different concentrations of methyl mercury standard solutions, incubation is carried out for 5 minutesafter mixing, a sodium borohydride solution is added to prepare nano seed crystal by reduction, a hydroxylamine hydrochloride solution and a chloroauric acid solution are sequentially added then, a solution color is recorded after fully and uniformly mixing, a standard color card is established, the absorbance of the solution is determined by a microplate reader and corresponds to the concentration of methyl mercury, and a standard work curve is established. Operation is carried out by replacing the methyl mercury standard solution with a marine product extracting solution, a corresponding solution color is recorded and compared with the standard color card, the absorbance of the solution is detected and substituted into the standard curve, so that organic mercury in a marine product is detected. The method is simple, sensitive, stable and high in anti-interference capability, does not need heating, can be used to complete detection within 30 minutes, and is low in detection cost.

The invention relates to a method for preparing alpha-sulfonic fatty acid ester by sulfonating fatty acid ester, comprising the following steps: injecting the fatty acid ester and a sulfonating agent into a micro-structural reactor (5) and a reactor (6) inside diameter of which is a micro passage respectively, mixing and sulfonating the fatty acid ester and the sulfonating agent, controlling the reaction temperature between 50 and 100 DEG C, and controlling the reaction materials to stay for 1ms to 1s in the micro-structural reactor (5) and stay for 0.5 to 30 minutes in the micro-passage reactor (6); and then injecting the reaction materials into a micro-passage reactor (7), aging the reaction materials at a reaction temperature between 50 and 100 DEG C, and controlling the reaction materials to stay for 0.5 to 30 minutes in the micro-passage reactor to obtain the alpha-sulfonic fatty acid ester. In the method, the novel micro-structural reactor is adopted, the defect of difficult control due to strong reaction heat release in the prior art is overcome, the materials can be mixed evenly, the released reaction heat can be removed in time, the reaction time can be controlled accurately, and the method has the advantages of good sulfonating efficiency, simple and safe operation and good product quality.

The invention discloses a full-automatic immunofluorescence detection device, which comprises a main frame. The main frame is provided with a test operation area, a sample adding area and a detection area. The detection area consists of a reagent card tray transmission mechanism, a scanning mechanism and a temperature controlled incubation mechanism. The sample adding area consists of a sample loading mechanism, a Tip head mechanism and a sample adding mechanism. The detection area consists of an optical detection mechanism and detection software. The scanning mechanism and the temperature controlled incubation mechanism are connected to the detection software, the scanning mechanism is disposed at the upper end of the reagent card tray transmission mechanism, the rear end of the reagent card tray transmission mechanism is equipped with a sample adding platform, reagent cards are sent into the temperature controlled incubation mechanism through a push-card-into-incubation mechanism and an incubation card push mechanism, and the temperature controlled incubation mechanism is provided with a laser scanning mechanism. By adopting the full-automatic immunofluorescence detection device provided by the invention, the detection process is automatically completed mechanically, the efficiency is improved, tedious manual operation is saved, automatic detection is realized, and the detection time is saved. Therefore, the full-automatic immunofluorescence detection device is convenient for application to emergency rooms, laboratory departments and other public places, community hospitals and other occasions, has high cost performance and strong market competitiveness, and fills the domestic blank.

The invention relates to a method for preparing nanometer Ba(Fe0.5Nb0.5)O3 powder through a microwave hydrothermal method. The molar ratio of Ba(NO3)2 to Fe(NO3)3.9H2O to NbC15 is 2:1:1, according to the molar ratio, Fe(NO3)3.9H2O is added into a Ba(NO3)2 water solution, and then NbC15 hydrochloric acid solution is added and mixed uniformly; then the pH of the mixed solution is adjusted to be larger than 12, a coprecipitation precursor is formed, the coprecipitation precursor is transferred into a microwave hydrothermal reaction kettle and subjected to a reaction for 1-1.5 h at the temperature of 200-220 DEG C to obtain a material, and the obtained material is washed, dried and screened to obtain the nanometer Ba(Fe0.5Nb0.5)O3 powder. The method combines advantages of the microwave hydrothermal method and a traditional hydrothermal method, is fast and efficient, saves energy, and reduces the opportunity of impurity element doping; reaction time is short, the reaction temperature is low, the powder does not need to be subjected to the later-period high-temperature calcinations working procedure, and the prepared powder is high in purity, uniform in size distribution and good in dispersity.

The invention discloses a rapid high-temperature high-pressure dynamic acid rock experiment device and a rapid high-temperature high-pressure dynamic acid rock experiment method. The rapid high-temperature high-pressure dynamic acid rock experiment device comprises a liquid storage tank, a first magnetic stirrer, multiple reaction tanks, multiple second magnetic stirrers, and a temperature control component, wherein the first magnetic stirrer is used for stirring the liquid storage tank; the multiple second magnetic stirrers correspond to the reaction tanks one by one; the temperature control component is used for performing temperature control on the reaction tanks and the liquid storage tank. The rapid high-temperature high-pressure dynamic acid rock experiment device also comprises a control component, wherein the control component comprises first pipelines and second pipelines which are communicated with the liquid storage tank and each reaction tank; a first valve and a second valve are arranged on each first pipeline; a pressurization source is arranged between each first valve and the corresponding second valve; and the first valves and the second valves are opened at intervals. According to the device and the method disclosed by the invention, the test results can be rapidly and accurately obtained.

The invention relates to a method for treating molten iron in a production process of spheroidal graphite cast iron, vermicular graphite cast iron or molten iron desulphurization. According to the method, a spheroidizing agent, a vermicular agent or a desulfurizing agent are put into a reaction chamber formed in a molten iron treatment ladle for treating the molten iron, wherein an inwards protruded type annular belt and the reaction chamber are arranged in the molten iron treatment ladle; magnesium steam generated during molten iron reaction is diffused outwards through the charging hole of the reaction chamber and a decompression groove. Therefore, the problems of moving and upward floating of the spheroidizing agent, the vermicular agent or the desulfurizing agent after melting loss are solved, the problems of strong reaction and low absorption rate of effective elements during treatment of the molten iron in the ladle are solved, the reaction time of the molten iron is accurately controlled, the product quality is improved, the production cost is reduced, the operation is simple and convenient, the resources are brought into full play and utilized, and the production environment is remarkably improved; in addition, the molten iron in the molten iron treatment and pouring processes is slightly cooled, the absorption rate of the effective elements is high, and the consumption of rare earth element RE can be reduced by 50-75%.

The invention discloses a method for preparing 4,5-dinitroimidazole by using a microchannel reactor. The method uses a micro-mixer to strengthen the mixing of raw materials. Unlike traditional reactors where the degree of uniformity is limited by the uneven flow field generated by stirring, the flow focusing technology adopted by the HPIMM micro-mixer can force two streams of fluid thin laminar flow Through the converging chamber, an efficient and uniform thin-layer contact reaction is produced, the stoichiometric ratio of the reactants is precisely controlled, and the amount of strong acid is reduced from the source, and the reaction is caused by the amount of acid and temperature changes in the traditional tank reactor. The generation of multi-nitration by-products eliminates mass transfer resistance and thus avoids the generation of hot spots, and solves the huge safety problem caused by the intense heat release of 4,5-dinitroimidazole in conventional reactors. The present invention utilizes the microsystem to synthesize 4-nitroimidazole and 4,5-dinitroimidazole to obtain high yields of 96.1% and 92.4%.

The invention provides a micro-channel reaction device, a module of the micro-channel reactor "heart-shaped" structure, with an inverted Ω-shaped blending tank inside the heart-shaped, and the blending tank has an everted opening and a narrower Bundle neck, larger lungs. When the equipment is used for the preparation of halogen-free organophosphorus flame retardants, phosphorus oxychloride and isooctanol or ethylene glycol monoether are respectively fed into the pre-cooling module of the micro-channel reactor through a metering pump, and the pre-cooled materials Enter the heart-shaped reaction module, and stay in the mixing tank for a short time, and the reaction solution is discharged after passing through the reaction module. The micro-channel reactor of the present invention enables the materials to be mixed more fully in the blending tank inside the reactor, the reaction efficiency is greatly improved, the reaction time is reduced, and there are almost no side reactions.