The invention discloses a multi-layer photocurable resin comprehensive covering package method for an organic electronic device. The method comprises a step of transferring a sample into a nitrogen glove box and applying an inert UV curing protective adhesive on an organic device, a step of applying a high-water-oxygen barrier UV curing adhesive on glass or flexible cover plate (high water-oxygenbarrier film) in the nitrogen glove box, covering the sample with a package covering layer with the completion of application, and smoothing and pressing, and a step of placing the device under a UV lamp to cure to complete packaging and bonding. Compared with the prior art, the present invention has the following advantages that the packaging process and materials consider the protection of the device, at the same time, the package is completed as quickly as possible, and the risk of device damage is reduced. During the packaging process, a package layer can completely cover the device, and the steps of etching, positioning and printing are reduced. In this way, the device can be protected from accidental damage, the application rate can be reduced, and the process cost is reduced.