The invention relates to a waxberry general flavone preservative solution which is prepared by dissolving waxberry general flavone with water. The waxberry general flavone is prepared through the following steps of: taking freshing waxberry fruits, drying the fresh waxberry fruit, then pulverizing the dried fresh waxberry fruit, adding 95% ethanol of which the weight is 4-6 times of that of the fresh waxberry fruit powder so as to soak the fresh waxberry fruit powder for 20-24 hours, performing ultrasonic-assisted extraction for 30-45 minutes, repeatedly extracting for 1-3 times so as to obtain an extracting solution, recovering the solvent, and concentrating the extracting solution to obtain an extract; and dispersing the extract in water, respectively extracting the solution with petroleum ether, chloroform and ethyl acetate, taking an ethyl acetate extract, dissolving the ethyl acetate extract with water, performing adsorption by use of macroporous resin, then performing elution by use of 15%-65% ethanol, collecting an eluant, and performing vacuum drying on the eluant, thereby obtaining the waxberry general flavone powder. The invention also relates to application of the waxberry general flavone preservative solution in the aspect of freshness preservation of aquatic products. The preparation method of the preservative solution is simple, and the waxberry general flavone preservative solution is capable of effectively inhibiting bacterial reproduction of fishes during a low-temperature storage process, retarding fat oxidation, delaying corruption and metamorphism, and thus prolonging the shelf life.