35results about How to "Reduce the cost of waste treatment" patented technology

The invention provides a method for extracting pectin from fermented hawthorn wine pomace. The method comprises the following steps: distilling fermented hawthorn pomace with the ratio of the fermented hawthorn pomace to water being (1-2):2; leaching the distilled residue at 85-95 DEG C for an hour; decolorizing by using granular activated carbon (washed by 1%-5% (m / v) deionized water) at 80 DEG C for 30-90 minutes, carrying out low-temperature alcohol participation by using alcohol of which the concentration is 55% (V / V) at 5 DEG C for 12 hours and carrying out room-temperature alcohol washing by using the alcohol of which the concentration is 70% (V / V) for 1 hour; further hydrolyzing protopectin in the pomace into soluble pectin and transferring the soluble pectin into water, and carrying out filter pressing to obtain a filtrate; merging the filtrate with distilled raffinate, and centrifuging, so as to obtain a clear and transparent pectin solution; and carrying out decolorizing by utilizing granular activated carbon washed by deionized water and alcohol participation on the pectin solution, drying and crushing to obtain hawthorn pectin powder. Compared with an acid hydrolysis method, no acid is added to the pectin extraction process, a new acid substance is prevented from being introduced to the system, and the difficulty is reduced for development and utilization of the residue after pectin extraction.

The invention relates to a continuous production system of lithium hexafluorophosphate. The continuous production system comprises a phosphorus pentafluoride generator (2), a micro-channel reactor A (3), a gas-liquid separator A (4), a micro-channel reactor B (6) and a gas-liquid separator B (7), the gas generated by the phosphorus pentafluoride generator (2) is introduced into the micro-channel reactor A (3), the material output by the micro-channel reactor A (3) enters the gas-liquid separator A (4), the gas separated by the gas-liquid separator A (4) enters the micro-channel reactor B (6),and is used as a reaction raw material so as to continuously react, the material output by the micro-channel reactor B (6) enters the gas-liquid separator B (7), and a liquid component is separated out by the gas-liquid separator B (7) and is conveyed into the micro-channel reactor A (3). According to the invention, the raw materials and the by-products are recycled, so that the conversion rate and the utilization rate of the raw materials are improved, and the cost is reduced.

The invention provides a 2-methyl-4-chlorophenoxyacetic acid preparation method, which comprises: carrying out a condensation reaction on sodium o-cresolate and sodium chloroacetate under the catalysis of a trimethylamine catalyst to obtain 2-methyl sodium phenoxyacetate, acidifying, and chlorinating to obtain 2-methyl-4-chlorophenoxyacetic acid. According to the present invention, under the catalysis of the trimethylamine catalyst, sodium o-cresolate and sodium chloroacetate can be subjected to the condensation reaction in the near-neutral environment with the temperature of lower than 70 DEGC, such that the main side reaction for hydrolyzing sodium chloroacetate into sodium glycolate is greatly reduced, the produced wastewater contains less o-methylphenol and glycolic acid (or sodium glycolate) so as to easily meet the nationally acceptable emission standards at a low treatment cost, the resource utilization of the waste acid solution can be achieved, the cost of the raw materials and the three-waste treatment cost are reduced, the purity of 2-methyl-4-chlorophenoxyacetic acid is higher than 95%, and the total yield is higher than 93%.

The invention relates to an industrial preparation method of cisatracurium besylate. The preparation method simplifies the refinement operation process, and obtains the high-purity cisatracurium besylate in a non-chromatographic column chromatography preparation mode under the condition of not changing the salt base for the first time. The preparation method can greatly shorten the production cycle, enhance the productivity and increase the yield to 45% above. In the product, the content of cisatracurium besylate is not lower than 98%, the content of total impurities does not exceed 2%, the content of mono quaternary ammonium salts does not exceed 0.2%, the content of other maximum individual impurities does not exceed 0.3%, and the content of isomers does not exceed 0.1%.

The invention relates to the field of herbicides, and discloses a preparation method of quinclorac, which comprises: 1) adopting an N-hydroxyphthalimide compound and azodiisobutyronitrile as catalysts, adopting oxygen as an oxidizing agent, and oxidizing 7-chloro-8-methylquinoline to obtain 7-chloro-8-quinoline carboxylic acid; and 2) by taking azodiisobutyronitrile as a catalyst, carrying out chlorination reaction on 7-chloro-8-quinoline carboxylic acid and chlorine to obtain 3,7-dichloro-8-quinoline carboxylic acid. By means of the method disclosed by the invention, the generation of a largeamount of waste acid and wastewater in a synthesis process can be reduced, and the product yield of quinclorac can be increased.

The invention discloses a method for producing nadroparin calcium from a heparin sodium crude product. The method comprises the following steps: dissolving the raw material crude product heparin sodium in water, precipitating by centrifugation and secondary salting-out to remove impurities in the heparin sodium crude product, carrying out nitrous degradation and reduction to obtain low-molecular heparin containing free sulfates, adding barium chloride to remove the free sulfates generated by degradation, and using an anion exchange resin and adjusting to appropriate parameters to carry out calcium conversion and final impurity removal; and finally, carrying out oxidation decolorization, sterile filtration and dehydration to obtain the nadroparin calcium raw material. By using the crude product heparin sodium as the raw material, the production cost is lowered; the technical steps are simplified to enhance the yield of the nadroparin calcium and reduce the titer loss of the nadroparin calcium; and the method can ensure the safety of the product, and is convenient for industrialized mass production.

The invention relates to a method for preparing cyanobenzene through ammoxidation, which mainly solves the problems that in the prior art, the cyanobenzene production cost is high, or the target product-cyanobenzene is low in yield, or the engineering enlargement effect of a reactor exists, or pollution of three wastes during production process is serious. The method adopts the technical scheme comprising the steps of taking toluene, ammonia gas and air as raw materials in a weight ratio of 1:(2-10):(2-10) on the conditions that the reaction temperature is 300-500 DEG C, the reaction pressure is 0.01-0.1Mpa and the catalyst (WWH) is 0.03-0.1 hour <1>, and conducting contact reaction on the raw materials and a fluid catalyst, thus producing cyanobenzene. The catalyst is a composite with a chemical formula in an atom ratio as follows: V1.0SbaAbBcCdOx, wherein the A is selected from at least one of lithium, sodium, potassium, rubidium, caesium or compositions thereof; the B is selected from at least one of magnesium, calcium, barium, chromium, tungsten, molybdenum, manganese, ferrum, cobalt, nickel, tin or compositions thereof; and the C is selected from at least one of boron, phosphorus or compositions thereof; therefore, the problems in the prior art are better solved, and the cyanobenzene can be used for industrial production.

The invention relates to an industrial preparation method of cisatracurium besylate. The preparation method simplifies the refinement operation process, and obtains the high-purity cisatracurium besylate in a non-chromatographic column chromatography preparation mode under the condition of not changing the salt base for the first time. The preparation method can greatly shorten the production cycle, enhance the productivity and increase the yield to 45% above. In the product, the content of cisatracurium besylate is not lower than 98%, the content of total impurities does not exceed 2%, the content of mono quaternary ammonium salts does not exceed 0.2%, the content of other maximum individual impurities does not exceed 0.3%, and the content of isomers does not exceed 0.1%.

The invention discloses a new green industrial preparation method of highly pure dutasteride. The method is realized through a synthetic route represented by a figure shown in the specification. The preparation method is adopted to construct a steroid 1,2-olefinic bond in order to avoid raw materials being harmful to environment and having large toxicity, and use of a severely toxic oxidant DDQ is thoroughly avoided from a reaction principle; and the method has the advantages of high efficiency, high purity, greenization, clean industrialization, strong maneuverability and high yield, and the total yield of a two-step reaction is greater than 80%. An iodo intermediate is purified to easily control the quality of finished dutasteride, the purity of the obtained dutasteride product is not smaller than 99.5%, the content of any single impurity does not exceed 0.1%, and medicinal demands are completely met.

The invention discloses a method for synthesizing 2-normal-butyl-4- chloro-5-formylimidazole shown by a formula (I). Imidazolone shown in the formula (II) reacts with bis (trichloromethyl) carbonate shown by a formula (III) and formamide shown by a formula (IV) in an organic solvent for 1-10 hours at the temperature of 20 DEG C below zero to 200 DEG C, and reaction solution is hydrolyzed to obtain 2-normal-butyl-4-chloro-5-formylimidazole. The invention has mild reaction conditions, good selectivity, no generation of phosphorus wastewater and low cost of proposal of waste water, waste gases and waste residues, and is suitable for industrial production.

The embodiment of the invention discloses a method and device for treating waste liquid from a circuit board preparation and relates to the field of circuit board preparation. In the invention, waste liquid from a circuit board production line is directly used for acidifying organic waste liquid without adding any processing chemicals so as to directly remove the chemical oxygen demand of the organic waste liquid and reduce a large amount of alkali consumed in a waste acidic water treatment process. The method for treating waste liquid from a circuit board preparation comprises: mixing organic waste from plate grinding pretreatment and / or plating pretreatment with waste acidic water from development and / or membrane stripping treatment for reaction to form a waste liquid product; and separating and removing the waste liquid product. The method and the device are used for treating waste liquid from the circuit board preparation.

A re-utilizing treatment of calcium carbide furnace tail gas is carried out by preparing synthetic ammonia, desulfurizing, denitrifying and obtaining ammonia sulfate by-product. Its advantages include low cost, simple process, no secondary-environmental pollution and waste circulating utilization.

The invention relates to a continuous production system of lithium hexafluorophosphate. The continuous production system comprises a phosphorus pentafluoride generator (2), a micro-channel reactor A (3), a gas-liquid separator A (4), a micro-channel reactor B (6) and a gas-liquid separator B (7), the gas generated by the phosphorus pentafluoride generator (2) is introduced into the micro-channel reactor A (3), the material output by the micro-channel reactor A (3) enters the gas-liquid separator A (4), the gas separated by the gas-liquid separator A (4) enters the micro-channel reactor B (6),and is used as a reaction raw material so as to continuously react, the material output by the micro-channel reactor B (6) enters the gas-liquid separator B (7), and a liquid component is separated out by the gas-liquid separator B (7) and is conveyed into the micro-channel reactor A (3). According to the invention, the raw materials and the by-products are recycled, so that the conversion rate and the utilization rate of the raw materials are improved, and the cost is reduced.

The invention discloses a method for preparing diacetylacyclovir with 7-bit diacetylacyclovir. The 7-bit diacetylacyclovir, 2-oxa-1, 4-butanediol diethyl ester and acetic anhydride react in organic solvents at the controlled temperature of 30-150 DEG C for 1-30h under the action of trifluoromethanesulfonic acid ammonium salt catalysts, and the target product of diacetylacyclovir is obtained by means of separation and purification after reaction. The method is moderate in reaction condition, short in cycle and simple and convenient in operation, the reaction process is easy to control, the 7-bit diacetylacyclovir can be converted into the diacetylacyclovir, the conversion rate is high, and the product with high purity can be obtained by means of simple operation after conversion. By the aid of the conversion process, the cost for treating waste gas, waste water and waste residues is reduced, resource utilization rate is increased, and the method is suitable for industrial production.

The invention relates to a 5-fluctyosine preparation method suitable for industrial production, belonging to the technical field of pharmaceutical chemical synthesis. The method comprises the following steps: by using 2-methoxy-5-fluorouracil as a raw material, chlorinating with phosphorous pentachloride to obtain 2-methoxy-4-chloro-5-fluoropyrimidine, and concentrating the acidic water phase obtained by after-treatment for later use; carrying out amination reaction on the 2-methoxy-4-chloro-5-fluoropyrimidine and an aminating agent to obtain 2-methoxy-4-amido-5-fluoropyrimidine; and carrying out acidic hydrolysis on the 2-methoxy-4-amido-5-fluoropyrimidine by using the concentrated acidic water phase recycled from chlorination to obtain the 5-fluctyosine. The 5-fluctyosine preparation method provided by the invention has the advantages of high yield, convenient after-treatment and fewer three-waste pollutants, solves the problems of high virulent product consumption, difficulty in acidic waste gas treatment, high pollution, high cost and the like in the traditional technique, and is suitable for industrial production application. The total mole yield is up to 70% or above.

The invention relates to an antimonial ammoxidation catalyst which mainly solves the problem that in the prior art the catalyst is difficult to adapt for the requirement of a fluidized bed and requires raw materials with higher price and the target outcome m-phthalonitrile has low yield. The antimonial ammoxidation catalyst comprises a catalyst active component which is a combination with the following chemical formula by atomic ratio: V1.0SbaAbBcCdOx, wherein A is at least one type of metal out of lithium, sodium, kalium or rubidium or cesium; B is at least one type of metal out of magnesium, calcium, barium, chrome, tungsten, molybdenum, manganese, iron, cobalt, nickel or tin; and C is at least one type of metal out of boron or phosphor. The technical scheme better solves the problem and can be used for industrial production.

The invention discloses a method for preparing potassium alum with an aluminum-contained waste catalyst generated from petrochemical production. The method includes: adding sulfuric acid to the aluminum-contained waste catalyst subjected to drying treatment and generated from the production process of a petrochemical enterprise, performing stirring reaction under heating, controlling the mol ratio of Al<3+> to SO4<2> in a reaction system to obtain an aluminum sulfate extract; feeding the obtained aluminum sulfate extract to a reaction kettle, heating to add a saturated sulphate solution, performing stirring reaction, controlling the molar feed ratio of K<+> to Al<3+> to SO4<2> in a reaction system, performing immediate filtration to obtain a filtrate, and performing cooling crystallization and filtration to obtain a coarse potassium alum filter cake with the filtrate to be treated; crushing the coarse potassium alum filter cake, and washing the crushed coarse potassium alum filter cake by adding water to obtain the potassium-alum finished product via filtration and centrifugal dewatering. With the method, resources are saved, environment is protected, and resources are recycled; the method is simple in step and free of relying on expensive experiment and being constrained by rigorous process elements.

The invention provides a vacuum infusion epoxy resin system and a preparation method and application thereof. The vacuum infusion epoxy resin system of the present invention uses epoxy diluent raw materials including polyepoxy tar containing cyclododecane structure, and can obtain A vacuum infusion epoxy resin system with above-moderate initial mix viscosity, low midpoint peak exotherm temperature and long workability time. The present invention provides a vacuum infusion epoxy resin system, the epoxy resin system is prepared by mixing A component and B component, wherein the A component includes bisphenol A epoxy resin and epoxy diluent, The B component includes a polyetheramine curing agent and an alicyclic amine; the epoxy diluent includes a polyepoxy tar containing a cyclododecane structure, and optionally other epoxy diluents.

The invention relates to the field of herbicide synthesis, particularly to quinmerac and a preparation method thereof. The method includes the steps: in the presence of a catalyst, carrying out an oxidation reaction on 3,8-dimethyl-7-chloroquine as a raw material, carboxylic acid as a solvent and oxygen-containing gas as an oxidizing agent, wherein the catalyst is one or more of a cobalt metal compound, a manganese metal compound and a vanadium metal compound. According to the method, a large amount of waste acid and waste water can be prevented from being generated, environmental protection is achieved, and the three-waste treatment cost is greatly reduced; and the method has the advantages of mild reaction conditions, simple post-treatment and high product purity and yield, and is very suitable for industrial production.

The invention discloses a method for producing nadroparin calcium from crude heparin sodium. The present invention uses crude heparin sodium as a raw material, after adding water to dissolve, and then precipitates and removes impurities in the crude heparin sodium by centrifugation and secondary salting out, then degrades and reduces with nitrous acid to obtain low-molecular-weight heparin containing free sulfate radicals, and then adds chlorinated Barium removes free sulfate radicals produced by degradation, then uses anion exchange resin, and adjusts appropriate parameters for calcium conversion and final impurity removal, and finally oxidative decolorization, filter sterilization, dehydration and drying to obtain nadroparin calcium raw material. The invention uses crude heparin sodium as a raw material, reduces the production cost, improves the yield of nadroparin calcium by simplifying the process steps, reduces the potency loss of the nadroparin calcium, can ensure the safety of the product, and is convenient for large-scale industrial production.

The invention discloses a preparation method of methyl p-methoxycinnamate. Add methyl acetate, methanol, sodium methoxide and cyclic ether into the condensation reactor, and react at reflux temperature; then add p-methoxybenzaldehyde, and circulate the reaction solution through the reaction bed filled with catalyst, After the addition of benzaldehyde is completed, the reaction is continued by reflux and insulation, and the water generated by the reaction is separated and removed. By adding methanol and cyclic ether and removing the generated water, the amount of catalyst used can be reduced to a very low level. By circulating the reaction solution through the reaction bed equipped with metal oxide catalysts, the 3 generated in the reaction process ‑Methoxy‑3‑methyl p-methoxyphenylpropionate is converted into methyl p-methoxy cinnamate in time, which improves the purity and yield of the product, and at the same time does not require acid-base neutralization process, and does not generate excess waste water and Compared with traditional processes, other solid wastes have equivalent or higher conversion rates and selectivity, lower production costs, and are more environmentally friendly.

The invention discloses a preparation method of m-trifluoromethyl acetophenone oxime. On the premise of not adding an organic solvent, the diazo liquid prepared by diazotization of nitrosyl sulfuric acid and m-trifluoromethylaniline reacts with acetaldehyde oxime to obtain the m-trifluoromethylacetophenone oxime suspension, and the product with high content is directly extracted by a steam distillation method. According to the preparation method, the obtained product is high in content, the synthesis process is simple, easy to implement, economical and environmentally friendly, and the long-term strategic target of green and sustainable development is met.

The invention discloses a preparation method for methyl p-methoxycinnamate. The preparation method comprises the following steps: adding methyl acetate, methanol, sodium methoxide and cyclic ether areinto a condensation reactor and performing a reaction at a reflux temperature; then adding p-methoxybenzaldehyde, and allowing a reaction solution to cyclically pass through a catalyst-loaded reaction bed at the same time; and after completion of the addition of p-methoxybenzaldehyde, carrying out reflux treatment, continuing the reaction under a heat preservation condition, and separating and removing water formed in the reaction. According to the invention, the use amount of a catalyst can be reduced to a low level by adding methanol and cyclic ether and removing the formed water; as the reaction solution cyclically passes through the reaction bed loaded with a metal oxide catalyst, 3-methoxy-3-p-methoxyphenylpropionate generated in the process of the reaction is timely converted into methyl p-methoxycinnamate, so the purity and yield of the product methyl p-methoxycinnamate is improve; meanwhile, the process of acid-base neutralization is not needed, so unwanted waste water and other solid waste are not produced; and compared with traditional processes, the preparation method of the invention has the advantages of higher conversion rate and selectivity, lower production cost and better environmental protection performance.

The invention provides a method for extracting pectin from fermented hawthorn wine pomace. The method comprises the following steps: distilling fermented hawthorn pomace with the ratio of the fermented hawthorn pomace to water being (1-2):2; leaching the distilled residue at 85-95 DEG C for an hour; decolorizing by using granular activated carbon (washed by 1%-5% (m / v) deionized water) at 80 DEG C for 30-90 minutes, carrying out low-temperature alcohol participation by using alcohol of which the concentration is 55% (V / V) at 5 DEG C for 12 hours and carrying out room-temperature alcohol washing by using the alcohol of which the concentration is 70% (V / V) for 1 hour; further hydrolyzing protopectin in the pomace into soluble pectin and transferring the soluble pectin into water, and carrying out filter pressing to obtain a filtrate; merging the filtrate with distilled raffinate, and centrifuging, so as to obtain a clear and transparent pectin solution; and carrying out decolorizing by utilizing granular activated carbon washed by deionized water and alcohol participation on the pectin solution, drying and crushing to obtain hawthorn pectin powder. Compared with an acid hydrolysis method, no acid is added to the pectin extraction process, a new acid substance is prevented from being introduced to the system, and the difficulty is reduced for development and utilization of the residue after pectin extraction.

The present invention relates to the field of herbicides, in particular to a preparation method of 7-chloro-8-quinoline carboxylic acid, the method comprising the following steps: 1) dissolving N-hydroxyphthalimides as a catalyst In the reaction liquid of compound and azobisisobutyronitrile, with oxygen as oxidant, 7-chloro-8-methylquinoline is oxidized to obtain 7-chloro-8-quinoline carboxylic acid; 2) the oxidation of step 1) The product is separated into solid and liquid to obtain a solid phase and a reaction liquid phase. Through the method of the invention, the production of a large amount of waste acid and waste water in the synthesis process can be avoided, and the reaction liquid phase can be recovered and used mechanically.

The invention discloses a new green industrial preparation method of highly pure dutasteride. The method is realized through a synthetic route represented by a figure shown in the specification. The preparation method is adopted to construct a steroid 1,2-olefinic bond in order to avoid raw materials being harmful to environment and having large toxicity, and use of a severely toxic oxidant DDQ is thoroughly avoided from a reaction principle; and the method has the advantages of high efficiency, high purity, greenization, clean industrialization, strong maneuverability and high yield, and the total yield of a two-step reaction is greater than 80%. An iodo intermediate is purified to easily control the quality of finished dutasteride, the purity of the obtained dutasteride product is not smaller than 99.5%, the content of any single impurity does not exceed 0.1%, and medicinal demands are completely met.

The invention discloses a dye penetrant inspection wastewater treatment agent, which is prepared from the following components in parts by weight: 2 to 4 parts of peroxide, 0.2 to 0.4 part of soluble ferrous salt and 0.8 to 3 parts of aluminum salt, wherein the peroxide is selected from any one or two of magnesium peroxide, zinc peroxide, calcium peroxide and sodium peroxide; the soluble ferrous salt is any one or more of ferrous sulfate, ferrous chloride and ferrous nitrate; and the aluminum salt is one or two of aluminum chloride or aluminum sulfate. According to the invention, a Fenton system is formed by .OH generated by the reaction of peroxide and water and the ferrous salt, COD in the dye penetrant inspection wastewater is removed, and the peroxide, the ferrous salt and the aluminum salt in the components of the treatment agent for the dye penetrant inspection wastewater are all solids, so that the treatment agent is convenient to store and low in cost. The invention also discloses a method for treating colorant wastewater by using pickling wastewater, which utilizes the pickling wastewater generated in the inspection and maintenance process of metal workpieces to treat wastes with wastes and reduce the waste treatment cost.