The present invention provides plant nutrient drink having functions of preventing fatigue and losing weight and a preparation technology thereof. Every 1,000 ml of the plant nutrient drink is prepared from the following raw and accessory materials in parts by weight: at least one kind of 20.0-120.0 g of fresh Chinese wolfberry fruits, 4.0-20.0 g of dried Chinese wolfberry fruits and 6.0-48.0 g of radix astragali decoction pieces, 0.05-150.0 g of a sweetener, 2.7-3.3 g of a pH value stabilizer, 0.0006-22.2 g of nutrients, 0-0.100 g of a pigment, 0-0.10 g of a flavoring agent, and the balance water. The preparation technology comprises single or compound prescription pretreatment liquid of Chinese wolfberry fruits and radix astragali preparing, blending, homogenizing, pre-sterilizing, filling, post-disinfecting, outer packaging, factory inspecting, etc. The prepared compound health-care sports drink has health-care functions of preventing fatigue, losing weight, preventing oxidation, enhancing body immunity and helping lower lipids, supplements nutrition, can quickly, significantly and enduringly relieve fatigue feelings of athletes, easily fatigued people, people in sub-health statuses and populations with over mental and physical labor, helps obese people to lose weight, and is good in taste, rich in nutrition, advanced in technologies, free of stimulants and preservatives, and suitable for large quantities of drinking.