3 results about "Biotin-binding proteins" patented technology

Biotin-containing monomers, polymeric materials formed from the biotin-containing monomers, articles containing the polymeric materials, methods of making the articles, and methods of using the articles are provided. The articles can be used, for example, for affinity capture of biotin-binding proteins, including biotin-binding fusion proteins (i.e., a biotin-binding protein fused to another biomaterial). Articles that contain captured biotin-binding proteins can be further used for affinity capture of various biotin-containing biomaterials such as biotinylated proteins. The articles can also be used, for example, for affinity capture of biotin-binding fusion proteins where the fusion protein includes, for example, an enzyme or antibody.

Technologies for the prevention and / or treatment of Pseudomonas aeruginosa infections. Disclosed herein are fusion proteins comprising a PcrV and PopB Pseudomonas aeruginosa polypeptide fused to a biotin-binding protein. Aspects of the technology also relate to compositions comprising the fusion protein, methods of production of the fusion protein, nucleic acids encoding the fusion protein and cells comprising the same; and methods of use of the fusion protein to induce an immune response to Pseudomonas aeruginosa infections, including prevention and / or treatment of Pseudomonas aeruginosa infections.