33results about How to "Addressing palatability issues" patented technology

The invention provides kitasamycin microcapsule and a preparation method and application thereof, which pertains to a feed drug additive field, in particular relates to novel kitasamycin preparation and a preparation technique thereof, and the application thereof in the preparation of livestock and poultry antibiotic growth promoter. The kitasamycin microcapsule of the invention comprises the kitasamycin and medical auxiliary materials; the weight of the medical auxiliary materials is 2-16 times of that of the kitasamycin material; the microcapsule is prepared through mixing the kitasamycin with heated and melted medical auxiliary materials and spray cooling. The kitasamycin microcapsule eliminates the bitterness of kitasamycin, intensifies the delayed release function of kitasamycin, reduces the stimulation of the kitasamycin to the stomach and the damage and decomposition degree thereof in the stomach, and enhances the effective intestines concentration and the functioning time of kitasamycin; the method for preparing the kitasamycin microcapsule is a wholly close manufacturing process and a wholly close material conveying system, thus decreasing flying of dust and material loss with has high yield of the products.

An enrofloxacin immediate-release pellet relates to the field of veterinary medicine. The pellet core is composed of the following components by weight percentage: 10%-45% of enrofloxacin, 18%-86% of excipient, disintegrating 1% to 5% of disintegrating agent, 1% to 2% of binder; the coating solution has a weight gain of 2% to 30%. In addition, it also relates to the preparation method of the enrofloxacin immediate-release pellets. The invention can cover up the bitter taste of enrofloxacin, ensure the rapid disintegration and release of the preparation in the gastrointestinal tract, and simplifies the prescription compared with the commercially available preparations. There are few types of auxiliary materials, which reduces the preparation quality problem caused by uneven mixing of raw and auxiliary materials in the preparation process, and the preparation process is simple, the quality is stable and reliable, and the bioavailability of the drug in the animal body is significantly improved.

The invention discloses valnemulin hydrochloride sustained-release granules and a preparation method and application thereof.The valnemulin hydrochloride sustained-release granules are prepared from, by mass, 5-50% of valnemulin hydrochloride and the balance carrier auxiliary materials through the fluidized spraying technology.The carrier auxiliary materials are one or more of animal fat, beewax, carnauba wax, hydrogenated vegetable oil, stearyl alcohol, fatty acid monoglyceride, fatty acid di-glyceride and paraffin.The valnemulin hydrochloride sustained-release granules solve the problem that medicine stability is poor, improve product quality and stability, and prolong service life.The problems that medicine powder is high in irritation and poor in palatability are solved.The granules and feed are mixed to be supplied, the medicine is released slowly, effective blood concentration maintenance time is longer, the administration frequency is reduced, the bioavailability of valnemulin hydrochloride is improved, and the clinical use effect is remarkable.

The invention provides a tannin mixture for reducing or eliminating plant tannin astringency. The tannin mixture can reduce or eliminate tannin astringency. The invention also discloses a method for preparing the tannin mixture for reducing or eliminating plant tannin astringency and application thereof to animal feed. The palatability of the animal feed in which tannin is added can be effectively improved, animals' intestinal health can be improved, diarrhea is reduced, and the use of antibiotics is reduced.