The invention provides a cultivation method for greenhouse muskmelons. The cultivation method includes the steps that S1, muskmelon seeds are selected to be cultured, and muskmelon seedlings are obtained; S2, a melon field is selected, a greenhouse is erected, and soil preparation and ridging are carried out, wherein the greenhouse comprises a greenhouse frame, a greenhouse cover and a water and fertilizer irrigation device; S3, field planting is carried out, wherein during field planting, the water and fertilizer irrigation device is used for applying a nutrient solution to the muskmelon seedlings, and applying amounts are different according to different growth periods of the muskmelons. A preparation method of the nutrient solution includes the steps that honeysuckle flowers, wild achyranthes roots, radix sophorae flavescentis, phoenix tree leaves, thunder god vines, herba houttuyniae and butterfly bush are ground and smashed, ethyl alcohol with the volume fraction of 70%-80% and ethyl alcohol with the volume fraction of 60%-70% are sequentially used for extraction, extracting solutions are mixed, and a first extracting solution is obtained; chloroisobromine cyanuric acid, chlorothalonil, honey, mandipropamid, urea, plant ash, water and calcium superphosphate are added into the first extracting solution, the materials are mixed and stirred to be uniform, and the nutrient solution is obtained. According to the cultivation method, the produced muskmelons have good disease resistance and quality and high yield.