The invention relates to a defoaming agent with fast dispersion, low
cloud point, high temperature and
high pressure resistance, strong acid and strong alkali resistance, which is prepared from the following components in percentage by weight: 5%-50% of white
carbon black silicon paste, 1%-25% of terminated polyether modified polysiloxane, 0.1%-10% of spherical polysilsesquioxane, 1%-25% of compound polyether, 0.1%-10% of
thickening agent, 0.05%-0.5% of sterilizing agent and the balance of water, and the sum of the weight percentages of the components is 100%. The invention also provides a production process of the defoaming agent, which comprises the following steps of: stirring the white
carbon black silicon paste, the spherical polysilsesquioxane and the terminated polyether modified polysiloxane by using a
homogenizer to be fully mixed, then adding the compound polyether, the
thickening agent and the sterilizing agent, uniformly stirring, and continuously and quickly stirring for 25-35 minutes by using the
homogenizer to obtain the defoaming agent. The uniformly mixed polyether modified polysiloxane defoaming agent is obtained. The invention aims to provide the defoaming agent which is high in dispersion speed, low in
cloud point, resistant to high temperature and
high pressure and resistant to strong acid and strong alkali.