66results about How to "Promotes collagen synthesis" patented technology

The present invention provides a composition for preventing or treating periodontal diseases comprising an extract of Achyranthis radix, Ulmus cortex or a mixture thereof which inhibits the productions of superoxide, prostaglandin, and interleukin (IL-1.beta.) which are inducers for periodontal diseases and inhibits the enzyme activity of collagenase which decomposes collagen protein which is a substrate for the periodontal tissues, and at the same time promotes collagen protein synthesis, thereby treating periodontal diseases efficiently.

A fluid dispenser comprising:a fluid reservoir (1); anda body (6) receiving:a dispenser member (3) that is connected to the reservoir (1);an actuator member (4) for actuating the dispenser member (3);a dispenser and diffuser head (7) forming a fluid dispenser orifice (73) and an application wall (74) for applying the fluid coming from the dispenser orifice (73) onto the skin;a module (5) comprising at least one source of radiation (51), such as an LED, each emitting monochromatic light of 400 nm to 700 nm, and having an anti-inflammatory action and / or a stimulating action for stimulating skin-regeneration metabolisms;characterized in that the dispenser and diffuser head (7) comprises a source housing (78), and in that the body (6) comprises a module housing (65) wherein the module (5) is received, this module housing (65) communicating with the source housing (78) so that the source of radiation (51) extends in the source housing (78) of the head (7).

The present invention relates to an oral composition for improving the beauty of the skin, which exhibits the effects of reducing skin wrinkles and inhibiting wrinkle formation. The composition contains a collagen peptide and at least one selected from the group consisting of elastin protein, hyaluronic acid and vitamin C. Particularly, the composition contains the collagen peptide, the elastin protein, hyaluronic acid and vitamin C at the optimum ratio, and when it is taken into the human body, it has no side effect, maximizes the biosynthesis of collagen in the skin dermal layer, shows excellent in vivo retention rate, and exhibits the effects of inhibiting skin wrinkle formation, maintaining or improving skin elasticity and moisturizing the skin. Thus, the composition will be useful as a health functional food for improving the beauty of the skin and preventing skin aging.

Disclosed are methods for treating aging and photodamaged skin employing topical application of compositions which comprise at least one peptide manganese complex. Also disclosed are methods wherein the composition further comprises retinol, at least one retinol derivative, or a mixture thereof and methods wherein the composition further comprises active agents selected from active drug substances, emollients, sunscreen agents, skin lightening agents, skin protectants, skin conditioning agents, humectants, and mixtures thereof.

The present invention achieves bio-mechanical stimulation of collagen synthesis in skin cells and reduction of the appearance of fine lines and wrinkles on the skin by applying a polymeric composition onto the skin in a manner so as to create surface tension that mimics the natural mechanical tension found in youthful skin.

The invention relates to a synthetic bone material and a process for making the same. The synthetic bone material may comprise multiple phases of calcium phosphate. Another aspect of the invention is a porous filter, and the method of making the same, and wherein the porous filter is substantially similar to the process for forming the synthetic bone material.

The invention belongs to the field of cosmetics and particularly relates to a hydrogen containing gel mask. The hydrogen containing gel mask comprises a powder agent A and a gel agent B. The powder agent A is prepared from, by weight, 0.01-5% of potassium carbonate, 0.1-10% of sunflower seed oil, 0.1-5% of magnesium salt, 0.0001-0.5% of hydrogen, 0.1-5% of silica, 0.0001-0.05% of a pH buffering agent and the balance corn starch, wherein the total weight percentage is 100%. The powder agent B is prepared from, by weight, 1-20% of a polyalcohol moisturizing agent, 0.05-2% of a thickening agent, 0.001-1% of active additives, 0.1-5% of a cosmetically acceptable carrier and the balance water, wherein the total weight percentage is 100%. The hydrogen containing gel mask gives play to remarkable skincare efficacies of hydrogen, has anti-oxidation, anti-inflammatory, anti-radiation and anti-ultraviolet functions and is capable of remarkably resisting skin injuries caused by radiation and ultraviolet while promoting fibrocyte collagen synthesis, clearing free radicals and inhibiting keratinocyte death so as to achieve efficacies of radiation resisting, ultraviolet resisting, beautifying, acne removing and wrinkle resisting.

The present invention relates to a method for identifying materials having an efficacy for improving collagen turnover in the skin. The invention also concerns a composition containing a combination of a collagen-degrading active and a collagen synthesis-stimulating active for enhancing skin remodeling.

The invention discloses an exosome and hyaluronic acid combined wound dressing, and a preparation method and application thereof. The wound dressing is formed by wrapping mesenchymal stem cell exosome with hyaluronic acid hydrogel, and the hyaluronic acid hydrogel is obtained by repeatedly freezing and unfreezing a hyaluronic acid aqueous solution and then cross-linking the hyaluronic acid aqueous solution with carbodiimide hydrochloride and adipic dihydrazide. Correspondingly, the invention also discloses a preparation method of the exosome and hyaluronic acid combined wound dressing and application of the exosome and hyaluronic acid combined wound dressing in medicines or materials for promoting wound healing. The wound dressing combines the characteristics of the exosome of the mesenchymal stem cells and the hyaluronic acid hydrogel, can promote revascularization and collagen synthesis after being in contact with a wound surface so as to repair damaged tissues, is safe, reliable and good in biocompatibility, has an obvious promoting effect on healing of the wound surface, and is not easy to cause infection, and no scar is left after healing.

Disclosed is a compound which exhibits a higher effect of preventing wrinkle formation, a higher effect of improving wrinkles, a higher effect of making the skin beautiful, and a higher effect of improving skin quality than conventional retinol and retinol derivatives in a sustained manner. Further disclosed are a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient. More specifically disclosed are retinol-modified collagen in which a dicarboxylic acid is attached to at least one hydroxyl group of collagen and retinol is attached to a carboxyl group of at least one attached dicarboxylic acid, a method for producing the same, and an external composition for the skin and a sheet-shaped cosmetic each containing the same as an active ingredient.

Disclosed are compositions and corresponding methods of their use that include an extract from Quassia undulata, Biophytum petersianum, Allophylus africanus, Buchanania reticulata, Melanorrhoea laccifera, Canthium dicoccum, or Aporosa tetrapleura, or any combination thereof, or at least 1, 2, 3, 4, 5, 6, or all 7 of the extracts.

The invention relates to novel uses of rhodiola effective ingredient in prevention and cure for osteoporosis. As experiment demonstrates: the compound can obviously upgrade osteotropic protein bmp-2 and mRNA expression in an osteoporosis-resisting medicine screening model, obviously facilitates osteoblast proliferation of human, alkaline phosphatase activity and collagen synthesis and increase osteogenous bone formation, thereby possessing prospect of medicine for prevention and cure for osteoporosis.

The invention discloses a polypeptide essence with a multi-directional brightening effect and preparation technology thereof. The polypeptide essence with the multi-directional brightening effect comprises the following components of aloe vera extract, carnosine,pseudoalteromonasfermented productextract,a compound ofdendrobium stem extract, radix sophorae extract,Ningxia wolfberry fruit extract, and purple coneflower extract, a compound of reed extract, licorice root extract, angelica root extract, salvia miltiorrhiza root extract, dogwoodfruit extract, and boxthorn rootextract, a compound ofpseudo-ginseng root extract, astragalus membranaceusrootextract, and fructus ligustrilucidi extract,terminalia ferdinandianafruit extract; dihydrooatylo-anthranilic acid, humectant,and skin conditioning agents. According to the polypeptide essence with themulti-directional brightening effect and the preparation technology thereof, the dull yellow problem of skin is improved from multiple directions, meanwhile production water is replaced with the aloe extract, and a cold matching method is adopted to maximize efficiencyand integrity of active ingredients of the extracts.

The invention provides sipunculus nudus zymolytic protein peptide powder having effect of promoting trauma healing. Sipunculus nudus has efficacy of immunoregulation, bacteria resisting, inflammationresisting and peripheral analgesia; the protein peptide powder can stop bleeding of a traumatic part and has antibacterial and anti-inflammatory effects; an organism takes the protein peptide powder in to induce generation of protein peptide Pro-Hyp to affect fibroblast growth so as to promote collagen synthesis at a wound part and wound healing to prevent abnormal scar formation. During the process, the protein peptide powder has effect of promoting proliferation and migration of endotheliocytes and keratinocytes so as to promote vascularization, provide nutritional substance and oxygen for the wound and promote epidermal reepithelialization to quickly form a closed space to prevent infection.

A fluid dispenser including a fluid reservoir and a body receiving a dispenser member that is connected to the reservoir and an actuator member for actuating the dispenser member; a dispenser and diffuser head forming a fluid dispenser orifice and an application wall for applying the fluid coming from the dispenser orifice onto the skin; a module having a source of radiation emitting monochromatic light of 400 nm to 700 nm and having anti-inflammatory action and / or a stimulating action for stimulating skin-regeneration metabolisms. The dispenser and diffuser head include a source housing and the body includes a module housing communicating with the source housing so that the source of radiation extends in the source housing of the head.

The invention discloses essence for improving skin aging and damage, and belongs to the technical field of skin care product processing. The essence is prepared from the following ingredients including 1, 3-propanediol, glycerol, isononanoate cetearyl stearate, cetostearyl alcohol, ceteareth-20, glyceryl stearate, ceteareth-12, cetyl palmitate, serum protein, acetyl hexapeptide-8, hydrolyzed sodium hyaluronate, glyceryl acrylate / acrylic acid copolymers, propanediol, PVM / MA copolymers, sodium hyaluronate, lactose, milk protein, oligopeptide-1, arginine / lysine polypeptide, polyacrylate cross-linked polymers-6, tert-butyl alcohol, 1, 2-hexanediol, caprylyl glycol, benzoic acid, ethylhexylglycerin, p-hydroxyacetophenone and water. A preparation method of the essence comprises the following steps of (1) raw material weighing; (2) stirring treatment; (3) cold plasma-ultraviolet light circulation alternate treatment; (4) micro jet high-pressure homogenizing treatment; and (5) quality inspection and packaging. The finally prepared essence has the obvious anti-aging effect.

The invention relates to raw materials for a hydrogen-enriched facial mask and the hydrogen-enriched facial mask prepared by adopting the raw materials, belonging to the technical field of cosmetics.The raw materials for the hydrogen-enriched facial mask comprise an agent A and an agent B, wherein the agent A comprises the following components in percentage by weight: 10-40 % of sodium bicarbonate, 1-5 % of calcium salt, 0.1-10 % of hydrolyzed coral, and the balance of hydrolyzed collagen, and the agent B comprises the following components in percentage by weight: 25-40 % of a humectant, 0.1-0.5 % of citric acid, 0.001-1 % of a catalyst, 0.001-0.1 % of a preservative, and the balance of deionized water. The facial mask can be prepared by mixing the raw materials with any base material ofthe existing facial mask. The facial mask prepared by adopting the raw materials has high content of hydrogen and long storage time, thus good effects of resisting inflammation, resisting radiation and resisting ultraviolet rays are achieved, meanwhile, the injuries to the skin caused by radiation and ultraviolet rays are effectively repaired, moreover, the synthesis of fibrocyte collagen can be promoted, the free radicals can be eliminated, the death of keratinocytes can be inhibited, and finally, the efficacies of beautifying the features, removing pimples, resisting wrinkles and delaying senescence are achieved.

The invention provides an artificial ligament which comprises an inner core and an outer layer from inside to outside in sequence. The inner core is made of ozonized polyethylene glycol terephthalate, and the outer layer is made of polysaccharide or polymer polymerized from hydrophilic group contained allyl monomer and is grafted on a free radical locus of the inner core. A preparation method of the artificial ligament includes: subjecting a ligament of a polyethylene glycol terephthalate material to reaction with ozone so as to obtain the polyethylene glycol terephthalate with a free radical; under protection of inert gas, subjecting a solution containing monomer molecules and the polyethylene glycol terephthalate containing the free radical to sealed polymerization reaction so as to obtain the artificial ligament. The artificial ligament is good in biocompatibility, and capable of restraining bacterial infection, changing protein conformation adhered on surface of a material, reducing inflammation and promoting adhering, growing and fibroblast of fibroblast after being planted in a human body. Collagen protein synthesis on the surface of the artificial ligament is improved, and infiltration of new ligament tissue is facilitated.

The invention provides organic fruit and vegetable facial mask powder. The facial mask powder is characterized by being prepared from the following components according to a certain mass ratio: 6-10 parts of strawberry, 2-10 parts of Chinese olive, 8-13 parts of kiwi fruit, 11-19 parts of watermelon, 2-10 parts of cherry, 9-21 parts of mung bean, 10-21 parts of banana, 1-8 parts of tomato, 4-20 parts of grapefruit, 1-7 parts of Chinese cabbage and 1-8 parts of wax guard. By adopting the structure, fruits and vegetables used in the facial mask powder contain massive nutritional ingredients, vitamins and trace elements; through external application of the facial mask powder, skin elasticity, nourishment and gloss are improved very well, skin can be effectively moistened, acne marks can be effectively eliminated; and the facial mask powder has strong oxidation resistance since enriched vitamins can be used for promoting collagen synthesis, and melanin generation and metabolism can be reduced. The facial mask powder has the effects of keeping skin white and tender and preventing senescence.

Disclosed are methods for treating aging and photodamaged skin employing topical application of compositions which comprise at least one peptide manganese complex. Also disclosed are methods wherein the composition further comprises retinol, at least one retinol derivative, or a mixture thereof and methods wherein the composition further comprises active agents selected from active drug substances, emollients, sunscreen agents, skin lightening agents, skin protectants, skin conditioning agents, humectants, and mixtures thereof.

The present application discloses angiogenic peptides that cause intracellular calcium release in target cells and thereby induce proliferation, migration, and capillary-like tube formation in primary cultured endothelial cells. The angiogenic peptides can be used for preventing and / or treating angiognesis-related conditions, especially wound healing, treating foot and leg ulcers in a subject, etc. In addition, the angiogenic peptides can be used for cosmetics a constituent of cosmetics for aged skin, for examples, anti-wrinkle and skin whitening.

Disclosed is a photo-stimulation method and device with a light mixture. The method includes the following steps: providing a light-emitting diode (LED) illuminant which is a combination of a yellow LED and a red LED; and illuminating a subject by the LED illuminant to promote collagen synthesis, to suppress microbial growth, or to inhibit melanin synthesis, wherein the yellow LED is in an illuminance range from 1,000 to 3,500 lux, the red LED is in an illuminance range from 6,000 to 9,500 lux, and the number ratio of the yellow LED to the red LED is 0.5-2:0.5-2.

The invention discloses a composition preventing and controlling skin peeling. The composition comprises components of humectant, repair agent, desensitizer and relieving agent, the repair agent comprises one or more of collagen, ceramide, epidermis growth factors and centella asiatica extract; the relieving agent comprises one or more of allantoin, aloe extract, menthol lactate ester and a calendula extracting solution. The repair agent added in the composition can promote the growth of cells and delay the skin ageing; the added humectant can lock the skin moisture and maintain the balance ofwater and oil of the skin; the added relieving agent can relieve the skin, reduce the skin burden and promote the healthy growth of the skin; the added desensitizer can further improve the capabilityof resisting the outside by the skin; the effect among the components can calm down and relieve the skin, retain and supplement the moisture, effectively relieve the skin dryness and achieve the effect of preventing and controlling the skin peeling.

Disclosed is a photo-stimulation method employing an agonist agent, and a kit for introducing same. The method includes the following steps: providing a light-emitting diode (LED) illuminant which is a yellow, red, green, blue LED or a mixture of two or more kinds thereof, and an agonist agent which contains 0.5% to 2% calcium ion; and adding the agonist agent to a subject and illuminating the subject by the LED illuminant to promote collagen synthesis, to suppress microbial growth, or to inhibit melanin synthesis, wherein the yellow LED is in an illuminance range from 1,000 to 3,500 lux, the red LED is in an illuminance range from 6,000 to 9,500 lux, the green LED is in an illuminance range from 1000 to 5000 lux, and the blue LED is in an illuminance range from 3,000 to 7,000 lux.

The invention discloses exosome-containing anti-aging essence and a preparation method thereof. The exosome-containing anti-aging essence, in 100 parts by total mass, comprises the following components in parts by mass: 0.05 to 0.1 part of umbilical cord stem cell exosome, 20 to 30 parts of rose hydrosol, 8 to 10 parts of glycerol, 4 to 5 parts of bifidus yeast fermentation product lysate, 2 to 4 parts of hyaluronic acid, 3 to 6 parts of tremella fuciformis extract, 2 to 3 parts of oligopeptide-1, 1 to 2 parts of hydrolyzed collagen, 0.3 to 0.7 part of carnosine, 0.1 to 0.2 part of Carbomer U20, 0.2 to 0.8 part of EDTA-2Na, 0.1 to 0.3 part of antibacterial agent, 0.1 to 0.2 part of triethanolamine and the balance of sterile water. The exosome-containing essence disclosed by the invention uses simple components, adopts an oil-free formula, is refreshing in use feeling, does not need to be emulsified, and has the effects of preserving moisture for a long time, preventing skin aging and stretching wrinkles.

A composition for use in wound healing and therefor is disclosed. The multiple components of fish fertilized roe are extracted. By virtue of its ability as an anti-oxidant to eliminate free radicals, inhibition of tyrosinase activity and facilitate the mass secretion of collagen from skin fibroblasts in order to promote skin whitening, anti-aging and wound healing. Accordingly, skin all-round repair is achieved, which is used as a cosmetic raw material and a wound dressing.

The use of a fermented milk product comprising non-hydrolysed whey proteins which is substantially free of casein proteins for the purpose of improving skin firmness, by structuring collagen without promoting collagen synthesis, when topically applied to skin is provided.

The invention discloses a loss preventing and hair strengthening nourishing solution. The nourishing solution comprises components in percentage by mass as follows: 0.0005%-0.002% of a hair follicle activation factor, 0.01%-1% of vitamins, 0.05%-5% of amino acid, 0.01%-1% of microelements, 0.01%-20% of a transdermal agent, 0.02%-10% of a conditioner and the balance of water. Meanwhile, the invention discloses a preparation method of the nourishing solution. The hair follicle activation factor is taken as the core effective component of the loss preventing and hair strengthening nourishing solution and matched with other auxiliary scalp nutrients, all the components cooperate and can balance microcirculatory system of scalp and reconstruct scalp barriers; the nourishing solution can activate resting cells, repair damaged hair follicle and rapidly stop loss and strengthen hair. Besides, the nourishing solution directly supplies hair growth nutrients through scalp hair follicle, can strengthen hair roots, activate activity of hair follicle, dredge blood vessels and promote rapid growth of hair, and has significant effects on soft hair, dry hair, splitting, no gloss, scalp itching, more dandruff, more hair oil, climacteric hair loss, alopecia areata and sebrrheic alopecia.

The present invention relates to a new use of panduratin derivatives or a Kaempferia pandurata extract comprising the same. More particularly, the present invention relates to a composition for improving wrinkles and / or preventing aging, which comprises a panduratin derivative or a Kaempferia pandurata extract comprising the same. The said the panduratin derivative or the Kaempferia pandurata extract comprising the same induces cell proliferation, inhibits degradation of collagen, and promotes synthesis of collagen, therefore, it shows excellent activity in prevention of aging, particularly preventing, improving or treating wrinkle and it can be used as an effective ingredient in a cosmetic, food or pharmaceutical composition.